Lys102

Site Information
LWACkACkRkTTNAD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 458969

In vivo Characterization
Methods used to characterize site in vivo:	3H acetate labeling ( 3 ) , [14C] acetate labeling ( 3 ) , immunoassay ( 3 ) , immunoprecipitation ( 3 ) , mass spectrometry ( 1 ) , mutation of modification site ( 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) ( 3 ) , C2C12 (myoblast) ( 3 )

Downstream Regulation
Effects of modification on MyoD:	molecular association, regulation ( 2 , 3 ) , protein conformation ( 3 )
Effects of modification on biological processes:	cell differentiation, induced ( 3 ) , transcription, induced ( 3 )
Induce interaction with:	DNA ( 3 ) , p300 (human) ( 2 )

References
1	Li Y (2008) CST Curation Set: 4755; Year: 2008; Biosample/Treatment: tissue, colon/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989 Curated Info
2	Wei L, et al. (2008) Differential binding modes of the bromodomains of CREB-binding protein (CBP) and p300 with acetylated MyoD. Biochem Biophys Res Commun 368, 279-84 18222173 Curated Info
3	Sartorelli V, et al. (1999) Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program. Mol Cell 4, 725-34 10619020 Curated Info