Lys49
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Home > Acetylation Site Page: > Lys49  -  CTNNB1 (rat)

Site Information
TAPsLSGkGNPEEED   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 458938

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
NRK49F (fibroblast) ( 1 )

Upstream Regulation
Treatments:
PAA ( 1 )

Downstream Regulation
Effects of modification on CTNNB1:
activity, inhibited ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
interstitial fibrosis ( 1 )

References 

1

Chen DQ, et al. (2023) Poricoic acid A suppresses renal fibroblast activation and interstitial fibrosis in UUO rats via upregulating Sirt3 and promoting β-catenin K49 deacetylation. Acta Pharmacol Sin 44, 1038-1050
36470978   Curated Info

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