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Site Information |
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PDyNPEGkVtkRkHD SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 458921 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
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Downstream Regulation | |
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Effects of modification on Ku70: | |
Effects of modification on biological processes: | |
Inhibit interaction with: |
References | |
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Lakshminarasimhan M, Rauh D, Schutkowski M, Steegborn C (2013) Sirt1 activation by resveratrol is substrate sequence-selective. Aging (Albany NY) 5, 151-4
23524286 Curated Info |
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Chen CS, et al. (2007) Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation. Cancer Res 67, 5318-27
17545612 Curated Info |
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Cohen HY, et al. (2004) Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell 13, 627-38
15023334 Curated Info |