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Home > Phosphorylation Site Page: > Ser58  -  TH iso2 (human)

Site Information
SYTPTPRsPRFIGRR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448544

Upstream Regulation
Kinases, in vitro:
ERK1 (human) ( 2 ) , ERK2 (human) ( 1 )

Downstream Regulation
Effects of modification on TH iso2:
enzymatic activity, induced ( 2 )



Lehmann IT, et al. (2006) Differential regulation of the human tyrosine hydroxylase isoforms via hierarchical phosphorylation. J Biol Chem 281, 17644-51
16644734   Curated Info


Sutherland C, et al. (1993) Phosphorylation and activation of human tyrosine hydroxylase in vitro by mitogen-activated protein (MAP) kinase and MAP-kinase-activated kinases 1 and 2. Eur J Biochem 217, 715-22
7901013   Curated Info