Ser65
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Home > Phosphorylation Site Page: > Ser65  -  ID3 (human)

Site Information
VPRGTQLsQVEILQR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 297110002

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , U2OS (bone cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ATM (human) ( 1 )
Treatments:
ionizing_radiation ( 1 )

Downstream Regulation
Effects of modification on ID3:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
DNA repair, induced ( 1 )
Induce interaction with:
MDC1 (human) ( 1 )

References 

1

Lee JH, et al. (2017) ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability. Nat Commun 8, 903
29026069   Curated Info

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