Tyr438
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Home > Phosphorylation Site Page: > Tyr438  -  FAK iso2 (mouse)

Site Information
IIDEEDTyTMPSTRD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447888

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 3 ) , mutation of modification site ( 3 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
chloroquine ( 2 ) , deferoxamine ( 2 ) , fibronectin ( 2 ) , PP1 ( 2 ) , Sem3A ( 1 ) , trichostatin_A ( 2 )

References 

1

Chacón MR, Fernández G, Rico B (2010) Focal adhesion kinase functions downstream of Sema3A signaling during axonal remodeling. Mol Cell Neurosci 44, 30-42
20159040   Curated Info

2

Lim Y, Han I, Kwon HJ, Oh ES (2002) Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts. J Biol Chem 277, 12735-40
11821402   Curated Info

3

Zhang X, et al. (1999) Focal adhesion kinase promotes phospholipase C-gamma1 activity. Proc Natl Acad Sci U S A 96, 9021-6
10430888   Curated Info