Ser42
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Home > Phosphorylation Site Page: > Ser42  -  Myf-6 (mouse)

Site Information
PGSDGTLsPCQDQMP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2907503

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , C2C12 (myoblast) ( 1 ) , C3H10T1/2 (fibroblast) ( 1 )

Upstream Regulation
Regulatory protein:
MKK6 (mouse) ( 1 )
Putative in vivo kinases:
P38A (mouse) ( 1 )
Treatments:
SB203580 ( 1 ) , serum_withdrawal ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell differentiation, altered ( 1 ) , transcription, inhibited ( 1 )

References 

1

Suelves M, et al. (2004) Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes. EMBO J 23, 365-75
14739931   Curated Info

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