Ser266

Site Information
KLQAsAPsLTPI___ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 2907500

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:	HeLa (cervical) [GJB3 (mouse)] ( 2 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 1 )

Downstream Regulation
Effects of modification on GJB3:	activity, induced ( 2 ) , protein stabilization ( 2 )

References
1	Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22 21659604 Curated Info
2	Diestel S, Eckert R, Hülser D, Traub O (2004) Exchange of serine residues 263 and 266 reduces the function of mouse gap junction protein connexin31 and exhibits a dominant-negative effect on the wild-type protein in HeLa cells. Exp Cell Res 294, 446-57 15023533 Curated Info