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Site Information |
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VEEDEDLyDCVENEE SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 447865 |
Associated spectra: 2 CST |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
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Downstream Regulation | |
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Effects of modification on VAV1: | |
Effects of modification on biological processes: | |
Induce interaction with: |
References | |
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Tong H, et al. (2017) c-Abl tyrosine kinase regulates neutrophil crawling behavior under fluid shear stress via Rac/PAK/LIMK/cofilin signaling axis. J Cell Biochem 119
29058761 Curated Info |
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Kim HS, Long EO (2012) Complementary Phosphorylation Sites in the Adaptor Protein SLP-76 Promote Synergistic Activation of Natural Killer Cells. Sci Signal 5, ra49
22786724 Curated Info |
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Miletic AV, et al. (2006) Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation. J Biol Chem 281, 38257-65
17050525 Curated Info |
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Amarasinghe GK, Rosen MK (2005) Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain. Biochemistry 44, 15257-68
16285729 Curated Info |
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Gao C, Schaefer E, Lakkis M, Blystone SD (2005) Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes. J Biol Chem 280, 15422-9
15699036 Curated Info |