Lys233
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Home > Sumoylation Site Page: > Lys233  -  SATB2 (human)

Site Information
YKKYKKIkVERVERE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2894437

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
multiple myeloma ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , J558L (B lymphocyte) ( 1 )

Upstream Regulation
Regulatory protein:
PIAS2 (human) ( 1 ) , PIAS3 (human) ( 1 ) , PIAS4 (human) ( 1 )

Downstream Regulation
Effects of modification on SATB2:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Dobreva G, Dambacher J, Grosschedl R (2003) SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression. Genes Dev 17, 3048-61
14701874   Curated Info

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