Lys17
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Home > Sumoylation Site Page: > Lys17  -  hnRNP M (human)

Site Information
EVAAtEIkMEEEsGA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2894407

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 4 , 5 )
Relevant cell line - cell type - tissue:
HeLa (cervical) [SUMO2 (human), transfection, SUMO2 K0 Q87R (lysine-deficient SUMO2, with Q87R to create convenient Trypsin cleavage site)] ( 2 ) , HeLa (cervical) [SUMO2 (human), transfection] ( 4 ) , Jurkat (T lymphocyte) ( 5 )

References 

1

Lumpkin RJ, et al. (2017) Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. Nat Commun 8, 1171
29079793   Curated Info

2

Hendriks IA, et al. (2014) Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol 21, 927-36
25218447   Curated Info

3

Lamoliatte F, et al. (2013) Targeted identification of SUMOylation sites in human proteins using affinity enrichment and paralog-specific reporter ions. Mol Cell Proteomics 12, 2536-50
23750026   Curated Info

4

Matic I, et al. (2010) Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif. Mol Cell 39, 641-52
20797634   Curated Info

5

Possemato A (2010) CST Curation Set: 9357; Year: 2010; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: smK
Curated Info

6

Vertegaal AC, et al. (2004) A proteomic study of SUMO-2 target proteins. J Biol Chem 279, 33791-8
15175327   Curated Info