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Site Information |
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LkLDKkVsAQEVRkE SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 458400 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on Ezrin: | |
Effects of modification on biological processes: | |
Induce interaction with: |
References | |
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Du S, et al. (2020) Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells. Sci Rep
32647287 Curated Info |
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Zhan XH, et al. (2019) LOXL2 upregulates phosphorylation of ezrin to promote cytoskeletal reorganization and tumor cell invasion. Cancer Res 79
31409639 Curated Info |
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Yuan X, et al. (2017) MST4 kinase phosphorylates ACAP4 protein to orchestrate apical membrane remodeling during gastric acid secretion. J Biol Chem 292, 16174-16187
28808054 Curated Info |
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Jiang H, et al. (2015) Cell Polarity Kinase MST4 Cooperates with cAMP-dependent Kinase to Orchestrate Histamine-stimulated Acid Secretion in Gastric Parietal Cells. J Biol Chem 290, 28272-85
26405038 Curated Info |
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Iessi E, et al. (2015) Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells. PLoS One 10, e0126526
26010871 Curated Info |
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Yu H, et al. (2014) Spatial control of proton pump H,K-ATPase docking at the apical membrane by phosphorylation-coupled ezrin-syntaxin 3 interaction. J Biol Chem 289, 33333-42
25301939 Curated Info |
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Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21
23312004 Curated Info |
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Jin C, et al. (2006) PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Biochem Biophys Res Commun 341, 784-91
16438931 Curated Info |
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Zhou R, et al. (2003) Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. J Biol Chem 278, 35651-9
12840026 Curated Info |