Lys263
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Home > Sumoylation Site Page: > Lys263  -  ERM (human)

Site Information
PPPPQGFkQEYHDPL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2887208

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , immunoprecipitation ( 2 ) , modification-specific antibody ( 2 ) , mutation of modification site ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
H2O2 ( 2 )

Downstream Regulation
Effects of modification on biological processes:
transcription, inhibited ( 1 , 2 )

References 

1

Degerny C, de Launoit Y, Baert JL (2008) ERM transcription factor contains an inhibitory domain which functions in sumoylation-dependent manner. Biochim Biophys Acta 1779, 183-94
18243147   Curated Info

2

Degerny C, et al. (2005) SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity. J Biol Chem 280, 24330-8
15857832   Curated Info