Tyr580
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Home > Phosphorylation Site Page: > Tyr580  -  SHP-2 iso2 (human)

Site Information
REDSARVyENVGLMQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448493

Downstream Regulation
Effects of modification on SHP-2 iso2:
molecular association, regulation ( 2 )
Induce interaction with:
GAB2 (human) ( 2 )

References 

1

Jo A, et al. (2014) SHP-2 Binds to Caveolin-1 and Regulates Src Activity via Competitive Inhibition of CSK in Response to H2O2 in Astrocytes. PLoS One 9, e91582
24632723   Curated Info

2

Sha F, et al. (2013) Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains. Proc Natl Acad Sci U S A 110, 14924-9
23980151   Curated Info