Ser473
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RPHFPQFsysAsGtA   SwissProt Entrez-Gene
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Site Group ID: 447855

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 662 , 685 , 763 , 767 , 819 , 834 , 859 , 878 ) , electrophoretic mobility shift ( 848 , 874 ) , flow cytometry ( 7 , 281 , 434 , 545 , 744 ) , immunoprecipitation ( 4 , 13 , 26 , 30 , 32 , 35 , 41 , 49 , 50 , 51 , 73 , 83 , 90 , 96 , 138 , 167 , 189 , 196 , 205 , 225 , 246 , 251 , 272 , 293 , 434 , 437 , 448 , 451 , 458 , 479 , 486 , 531 , 852 , 903 ) , mass spectrometry ( 4 , 14 , 90 , 118 , 138 , 164 , 195 , 202 , 209 , 210 , 211 , 232 , 289 , 290 , 291 , 292 , 317 , 318 , 321 , 322 , 323 , 324 , 325 , 336 , 337 , 344 , 345 , 346 , 347 , 352 , 353 , 354 , 355 , 356 , 357 , 358 , 370 , 371 , 376 , 377 , 387 , 389 , 392 , 393 , 394 , 395 , 396 , 402 , 406 , 411 , 414 , 432 , 569 ) , mass spectrometry (in vitro) ( 294 ) , microscopy-colocalization with upstream kinase ( 496 , 505 , 826 , 838 , 842 ) , mutation of modification site ( 4 , 9 , 10 , 12 , 13 , 14 , 25 , 49 , 51 , 91 , 138 , 142 , 159 , 169 , 178 , 272 , 369 , 426 , 434 , 437 , 452 , 478 , 481 , 502 , 504 , 506 , 526 , 565 , 568 , 576 , 633 , 662 , 683 , 692 , 693 , 706 , 712 , 738 , 747 , 762 , 767 , 812 , 826 , 834 , 842 , 852 , 858 , 890 , 900 , 901 , 907 , 910 , 920 , 921 , 923 ) , peptide sequencing ( 39 , 47 , 108 , 391 , 424 , 924 ) , phospho-antibody ( 1 , 4 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 22 , 23 , 24 , 25 , 26 , 27 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 75 , 77 , 78 , 79 , 80 , 81 , 83 , 85 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 95 , 96 , 97 , 99 , 100 , 101 , 102 , 103 , 104 , 106 , 110 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 127 , 131 , 133 , 134 , 135 , 138 , 139 , 140 , 141 , 142 , 143 , 147 , 148 , 149 , 150 , 153 , 155 , 158 , 159 , 161 , 163 , 166 , 167 , 168 , 169 , 171 , 172 , 173 , 174 , 177 , 181 , 182 , 185 , 187 , 189 , 190 , 191 , 193 , 194 , 196 , 197 , 200 , 205 , 206 , 207 , 208 , 212 , 216 , 222 , 225 , 229 , 234 , 235 , 239 , 241 , 244 , 245 , 246 , 247 , 248 , 250 , 251 , 253 , 254 , 255 , 258 , 259 , 260 , 261 , 263 , 264 , 267 , 270 , 272 , 274 , 277 , 278 , 280 , 281 , 282 , 283 , 284 , 286 , 287 , 288 , 293 , 294 , 295 , 296 , 299 , 300 , 306 , 307 , 308 , 310 , 312 , 313 , 314 , 315 , 319 , 320 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 335 , 338 , 339 , 340 , 341 , 342 , 343 , 348 , 349 , 350 , 351 , 359 , 361 , 362 , 363 , 365 , 366 , 367 , 368 , 369 , 372 , 373 , 374 , 375 , 378 , 379 , 380 , 381 , 383 , 384 , 386 , 388 , 390 , 398 , 399 , 400 , 401 , 403 , 404 , 405 , 406 , 407 , 408 , 410 , 412 , 413 , 415 , 416 , 417 , 418 , 419 , 420 , 422 , 423 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 433 , 434 , 435 , 436 , 438 , 440 , 441 , 443 , 444 , 445 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 454 , 455 , 456 , 458 , 460 , 461 , 462 , 463 , 464 , 465 , 467 , 468 , 469 , 470 , 471 , 472 , 474 , 475 , 476 , 477 , 478 , 479 , 480 , 481 , 482 , 484 , 485 , 486 , 487 , 488 , 489 , 490 , 491 , 493 , 494 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 517 , 518 , 519 , 520 , 521 , 522 , 524 , 525 , 526 , 527 , 528 , 530 , 531 , 532 , 533 , 534 , 536 , 537 , 538 , 541 , 542 , 543 , 544 , 545 , 546 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 555 , 556 , 557 , 558 , 559 , 560 , 561 , 562 , 563 , 564 , 565 , 566 , 568 , 570 , 571 , 572 , 573 , 574 , 575 , 576 , 577 , 578 , 579 , 580 , 581 , 582 , 583 , 584 , 585 , 586 , 587 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 606 , 608 , 609 , 610 , 611 , 612 , 613 , 614 , 615 , 616 , 617 , 618 , 619 , 620 , 621 , 622 , 623 , 624 , 625 , 626 , 627 , 628 , 629 , 630 , 631 , 632 , 633 , 636 , 638 , 639 , 640 , 641 , 642 , 643 , 644 , 645 , 646 , 647 , 648 , 649 , 650 , 651 , 652 , 653 , 654 , 655 , 656 , 657 , 658 , 659 , 660 , 661 , 662 , 663 , 664 , 665 , 666 , 667 , 668 , 669 , 670 , 671 , 672 , 673 , 674 , 675 , 676 , 677 , 678 , 679 , 680 , 681 , 682 , 683 , 684 , 685 , 686 , 687 , 688 , 689 , 690 , 691 , 692 , 693 , 694 , 695 , 696 , 697 , 698 , 699 , 700 , 701 , 702 , 703 , 704 , 705 , 706 , 707 , 708 , 709 , 710 , 711 , 712 , 714 , 715 , 717 , 718 , 719 , 720 , 721 , 722 , 723 , 724 , 725 , 726 , 727 , 728 , 729 , 730 , 731 , 732 , 733 , 734 , 735 , 736 , 737 , 738 , 739 , 740 , 741 , 742 , 744 , 745 , 746 , 747 , 748 , 749 , 750 , 751 , 752 , 753 , 755 , 756 , 757 , 758 , 759 , 760 , 761 , 762 , 763 , 764 , 765 , 766 , 767 , 768 , 769 , 770 , 771 , 772 , 773 , 774 , 775 , 776 , 777 , 778 , 779 , 780 , 781 , 782 , 783 , 784 , 785 , 786 , 787 , 788 , 789 , 790 , 791 , 794 , 795 , 796 , 797 , 799 , 800 , 801 , 803 , 805 , 807 , 808 , 809 , 810 , 811 , 812 , 813 , 814 , 815 , 816 , 817 , 818 , 819 , 820 , 822 , 823 , 824 , 825 , 826 , 827 , 828 , 830 , 831 , 832 , 833 , 834 , 835 , 836 , 837 , 838 , 839 , 840 , 841 , 842 , 843 , 844 , 846 , 847 , 848 , 849 , 850 , 851 , 852 , 853 , 854 , 855 , 856 , 857 , 858 , 859 , 860 , 861 , 862 , 863 , 864 , 865 , 866 , 867 , 868 , 869 , 870 , 871 , 872 , 873 , 874 , 875 , 876 , 877 , 878 , 879 , 880 , 881 , 882 , 883 , 884 , 885 , 886 , 887 , 889 , 890 , 891 , 892 , 893 , 894 , 895 , 896 , 897 , 898 , 899 , 900 , 901 , 902 , 903 , 904 , 905 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 916 , 917 , 919 , 920 , 925 , 926 , 927 , 928 ) , phosphoamino acid analysis ( 228 , 279 , 382 , 508 , 852 ) , phosphopeptide mapping ( 834 ) , western blotting ( 1 , 4 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 22 , 23 , 24 , 25 , 26 , 27 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 75 , 77 , 78 , 79 , 80 , 81 , 83 , 85 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 95 , 96 , 97 , 99 , 100 , 101 , 102 , 103 , 104 , 106 , 108 , 110 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 127 , 131 , 133 , 134 , 135 , 138 , 139 , 140 , 141 , 143 , 147 , 148 , 149 , 150 , 153 , 155 , 158 , 159 , 161 , 163 , 166 , 167 , 168 , 169 , 171 , 172 , 173 , 174 , 177 , 178 , 181 , 182 , 185 , 189 , 190 , 191 , 193 , 194 , 196 , 197 , 200 , 205 , 206 , 207 , 208 , 212 , 216 , 222 , 225 , 228 , 229 , 234 , 235 , 239 , 241 , 244 , 245 , 246 , 247 , 248 , 250 , 251 , 253 , 254 , 255 , 258 , 259 , 260 , 261 , 264 , 267 , 270 , 272 , 274 , 277 , 278 , 279 , 280 , 282 , 284 , 286 , 287 , 288 , 293 , 294 , 295 , 296 , 299 , 300 , 306 , 307 , 308 , 310 , 312 , 313 , 315 , 319 , 320 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 335 , 339 , 340 , 341 , 342 , 343 , 348 , 349 , 350 , 351 , 359 , 361 , 362 , 363 , 365 , 366 , 367 , 368 , 369 , 372 , 373 , 374 , 375 , 378 , 379 , 380 , 381 , 382 , 383 , 384 , 386 , 388 , 390 , 391 , 398 , 399 , 400 , 401 , 403 , 404 , 405 , 406 , 407 , 410 , 412 , 415 , 416 , 417 , 418 , 419 , 420 , 422 , 423 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 433 , 434 , 435 , 436 , 437 , 438 , 440 , 441 , 443 , 444 , 445 , 447 , 448 , 449 , 450 , 451 , 452 , 454 , 456 , 458 , 460 , 461 , 462 , 463 , 464 , 465 , 467 , 468 , 469 , 470 , 471 , 472 , 475 , 476 , 477 , 478 , 479 , 480 , 481 , 482 , 484 , 485 , 486 , 487 , 488 , 489 , 490 , 491 , 493 , 494 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 517 , 518 , 519 , 520 , 521 , 522 , 524 , 525 , 526 , 527 , 528 , 530 , 531 , 532 , 533 , 534 , 536 , 537 , 538 , 541 , 542 , 543 , 544 , 546 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 555 , 557 , 558 , 559 , 560 , 561 , 562 , 564 , 565 , 566 , 568 , 570 , 571 , 572 , 573 , 574 , 575 , 576 , 577 , 578 , 579 , 580 , 581 , 582 , 583 , 584 , 585 , 586 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 606 , 608 , 609 , 610 , 611 , 612 , 613 , 614 , 615 , 616 , 618 , 619 , 620 , 621 , 622 , 623 , 624 , 625 , 627 , 628 , 629 , 630 , 631 , 632 , 633 , 636 , 638 , 639 , 640 , 641 , 642 , 644 , 645 , 646 , 647 , 648 , 649 , 652 , 653 , 654 , 655 , 656 , 657 , 658 , 660 , 663 , 665 , 666 , 668 , 676 , 677 , 681 , 683 , 684 , 687 , 688 , 689 , 692 , 694 , 696 , 698 , 700 , 701 , 702 , 703 , 704 , 705 , 706 , 707 , 710 , 711 , 714 , 715 , 717 , 718 , 722 , 723 , 724 , 726 , 727 , 729 , 730 , 731 , 732 , 733 , 735 , 736 , 738 , 740 , 746 , 747 , 748 , 755 , 756 , 757 , 758 , 761 , 763 , 764 , 765 , 766 , 767 , 769 , 771 , 772 , 775 , 776 , 777 , 778 , 780 , 781 , 782 , 785 , 786 , 787 , 788 , 789 , 790 , 794 , 795 , 796 , 800 , 801 , 803 , 805 , 807 , 809 , 811 , 812 , 814 , 816 , 817 , 818 , 820 , 823 , 825 , 826 , 827 , 828 , 830 , 831 , 832 , 834 , 835 , 836 , 837 , 839 , 840 , 842 , 843 , 844 , 846 , 847 , 849 , 851 , 852 , 853 , 857 , 858 , 860 , 861 , 862 , 864 , 865 , 867 , 869 , 872 , 875 , 884 , 885 , 887 , 890 , 896 , 897 , 900 , 901 , 902 , 903 , 904 , 905 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 916 , 920 , 924 , 925 , 926 , 927 , 928 )
Disease tissue studied:
ataxia-telangiectasia ( 320 ) , adrenal cancer ( 167 , 756 , 826 , 839 ) , pheochromocytoma ( 167 , 756 , 826 , 839 ) , bladder cancer ( 278 , 500 , 624 ) , bone cancer ( 82 , 158 , 177 , 367 , 412 , 447 , 460 , 518 , 584 , 696 ) , Ewing's sarcoma ( 518 ) , osteosarcoma ( 367 ) , brain cancer ( 32 , 41 , 48 , 106 , 190 , 258 , 274 , 300 , 313 , 348 , 365 , 368 , 379 , 412 , 415 , 441 , 452 , 585 , 586 , 602 , 609 , 647 , 648 , 663 , 685 , 733 , 747 , 759 , 859 , 896 , 908 , 928 ) , astrocytoma ( 685 , 859 ) , glioblastoma ( 32 , 41 , 48 , 106 , 258 , 274 , 300 , 313 , 348 , 365 , 412 , 452 , 585 , 586 , 602 , 609 , 647 , 648 , 663 , 733 , 747 , 759 , 896 , 908 ) , glioblastoma multiforme ( 138 , 190 , 258 , 313 , 379 , 441 , 609 , 647 , 759 ) , glioma ( 32 , 41 , 48 , 106 , 138 , 190 , 258 , 274 , 300 , 313 , 348 , 365 , 379 , 412 , 441 , 452 , 585 , 586 , 602 , 609 , 647 , 648 , 663 , 733 , 747 , 759 , 896 , 908 ) , medulloblastoma ( 415 ) , Schwannoma ( 368 , 928 ) , breast cancer ( 9 , 10 , 26 , 34 , 37 , 39 , 51 , 79 , 89 , 93 , 138 , 141 , 143 , 149 , 159 , 168 , 172 , 173 , 208 , 216 , 229 , 247 , 251 , 253 , 255 , 270 , 272 , 280 , 287 , 295 , 299 , 307 , 333 , 335 , 342 , 362 , 365 , 369 , 372 , 374 , 381 , 386 , 391 , 405 , 410 , 412 , 416 , 418 , 427 , 431 , 440 , 445 , 448 , 450 , 451 , 454 , 460 , 469 , 476 , 486 , 490 , 497 , 502 , 504 , 505 , 506 , 512 , 531 , 550 , 555 , 571 , 580 , 600 , 603 , 611 , 613 , 622 , 624 , 631 , 638 , 643 , 654 , 657 , 677 , 688 , 694 , 702 , 710 , 731 , 742 , 745 , 769 , 776 , 785 , 800 , 818 , 838 , 843 , 844 , 849 , 867 , 901 ) , breast adenocarcinoma ( 37 , 172 , 173 , 460 , 838 ) , breast cancer, triple negative ( 141 , 172 , 173 , 460 ) , cervical cancer ( 380 , 506 , 722 , 840 ) , cervical adenocarcinoma ( 506 , 840 ) , colorectal cancer ( 4 , 47 , 54 , 66 , 77 , 142 , 163 , 248 , 295 , 328 , 407 , 467 , 469 , 484 , 488 , 500 , 509 , 557 , 568 , 627 , 657 , 723 , 836 , 847 , 862 ) , colorectal carcinoma ( 4 , 47 , 54 , 66 , 77 , 142 , 163 , 248 , 295 , 328 , 407 , 467 , 469 , 484 , 488 , 500 , 509 , 557 , 568 , 627 , 657 , 723 , 836 , 847 , 862 ) , endometrial cancer ( 8 , 428 ) , endometrial adenocarcinoma ( 8 , 428 ) , gastric cancer ( 139 , 148 , 317 , 318 , 321 , 344 , 346 , 347 , 354 , 355 , 387 , 392 , 393 , 394 , 406 , 419 , 432 , 458 , 511 , 525 , 761 ) , gastric carcinoma ( 139 , 148 , 317 , 318 , 321 , 344 , 346 , 347 , 354 , 355 , 387 , 392 , 393 , 394 , 406 , 419 , 432 , 458 , 511 , 525 ) , GIST ( 761 ) , HNSCC ( 193 ) , kidney cancer ( 6 , 174 , 178 , 427 , 468 , 658 ) , papillary kidney cancer ( 87 ) , leukemia ( 1 , 43 , 46 , 58 , 62 , 102 , 104 , 191 , 235 , 378 , 389 , 417 , 475 , 487 , 510 , 533 , 543 , 643 , 692 , 710 , 764 , 828 , 911 , 913 ) , acute lymphocytic leukemia ( 543 ) , acute myelogenous leukemia ( 43 , 46 , 191 , 378 , 475 , 510 , 533 , 643 , 710 , 911 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 102 , 487 , 643 , 913 ) , chronic lymphocytic leukemia ( 828 ) , chronic myelogenous leukemia ( 18 , 58 , 62 , 389 , 417 , 692 ) , T cell leukemia ( 1 , 235 ) , liver cancer ( 33 , 35 , 76 , 83 , 96 , 117 , 135 , 140 , 267 , 283 , 399 , 400 , 422 , 514 , 526 , 583 , 593 , 603 , 608 , 639 , 701 , 704 , 714 , 801 ) , hepatocellular carcinoma ( 44 , 76 , 96 , 135 ) , squamous cell carcinoma of the liver ( 400 ) , lung cancer ( 15 , 17 , 24 , 52 , 54 , 66 , 75 , 81 , 85 , 99 , 113 , 115 , 116 , 133 , 187 , 194 , 212 , 241 , 244 , 270 , 287 , 322 , 323 , 324 , 325 , 328 , 341 , 345 , 350 , 352 , 353 , 356 , 357 , 358 , 362 , 376 , 377 , 395 , 406 , 412 , 436 , 446 , 450 , 454 , 455 , 467 , 485 , 488 , 495 , 527 , 538 , 583 , 606 , 630 , 631 , 636 , 656 , 672 , 684 , 758 , 771 , 886 ) , non-small cell lung cancer ( 15 , 17 , 24 , 29 , 52 , 54 , 66 , 75 , 81 , 85 , 99 , 113 , 115 , 116 , 133 , 187 , 194 , 322 , 323 , 324 , 325 , 341 , 345 , 350 , 352 , 353 , 356 , 357 , 358 , 376 , 377 , 395 , 406 , 436 , 446 , 450 , 488 , 527 , 538 , 630 , 631 , 636 , 656 , 684 , 886 ) , non-small cell lung adenocarcinoma ( 15 , 17 , 24 , 52 , 54 , 75 , 81 , 85 , 113 , 115 , 116 , 133 , 187 , 324 , 325 , 345 , 352 , 353 , 356 , 357 , 358 , 395 , 406 ) , non-small cell large cell lung carcinoma ( 15 , 24 , 115 , 187 ) , non-small cell squamous cell lung carcinoma ( 324 , 325 , 345 , 395 , 406 , 488 ) , lymphoma ( 25 , 131 , 281 , 373 , 383 , 384 , 465 , 528 , 543 , 592 , 620 , 643 , 725 , 809 , 816 ) , anaplastic large cell lymphoma ( 281 , 373 , 543 ) , B cell lymphoma ( 12 , 25 , 592 , 816 ) , Burkitt's lymphoma ( 592 ) , Hodgkin's lymphoma ( 384 , 725 ) , non-Hodgkin's lymphoma ( 25 ) , mantle cell lymphoma ( 25 ) , PEL ( 131 ) , T cell lymphoma ( 281 , 373 , 383 , 620 ) , neuroblastoma ( 80 , 118 , 246 , 259 , 277 , 479 , 513 , 537 , 585 , 604 , 641 , 755 , 756 , 825 , 827 , 872 , 926 ) , ovarian cancer ( 30 , 53 , 67 , 119 , 120 , 149 , 295 , 338 , 361 , 368 , 388 , 474 , 541 , 560 , 588 , 591 , 665 , 754 , 776 , 843 , 865 ) , ovarian epithelial carcinoma ( 541 ) , pancreatic cancer ( 11 , 19 , 29 , 54 , 55 , 69 , 71 , 74 , 189 , 263 , 365 , 467 , 522 , 612 , 687 , 711 , 735 ) , pancreatic carcinoma ( 11 , 19 , 55 , 69 , 71 , 74 , 189 , 365 , 467 , 522 , 612 , 687 , 711 , 735 ) , pancreatic islet cell cancer ( 29 ) , multiple myeloma ( 16 , 63 ) , prostate cancer ( 14 , 41 , 83 , 90 , 97 , 196 , 197 , 205 , 234 , 254 , 270 , 295 , 308 , 332 , 343 , 414 , 424 , 450 , 460 , 461 , 462 , 463 , 469 , 503 , 512 , 536 , 615 , 623 , 629 , 642 , 653 , 715 , 747 , 750 , 765 , 789 , 862 , 910 , 914 , 927 ) , melanoma skin cancer ( 61 , 207 , 351 , 425 , 434 , 504 , 621 , 627 , 649 , 738 , 820 ) , small intestine cancer ( 761 ) , fibrosarcoma of soft tissue ( 103 , 286 , 328 , 498 , 500 , 835 , 862 ) , leiomyosarcoma ( 286 ) , rhabdomyosarcoma ( 40 , 155 , 518 , 542 , 787 ) , cancer, squamous cell carcinoma ( 193 , 312 , 380 ) , thyroid cancer ( 614 , 706 ) , anaplastic thyroid carcinoma ( 706 ) , follicular thyroid carcinoma ( 614 , 706 ) , papillary thyroid carcinoma ( 706 ) , diabetes mellitus ( 530 ) , type 2 diabetes ( 288 , 530 ) , hepatitis ( 507 ) , neurofibromatosis type 1 ( 404 ) , Parkinson's disease ( 423 )
Relevant cell line - cell type - tissue:
'brain, caudate-putamen' ( 537 ) , 'brain, cerebellum' ( 415 ) , 'brain, midbrain' ( 423 ) , 'hematopoietic progenitor, CD34+'-blood ( 279 ) , 'macrophage, alveolar'-lung ( 893 ) , 'muscle, skeletal' ( 147 , 282 , 288 , 493 , 499 , 530 , 542 , 547 , 610 , 646 , 650 , 667 , 670 , 681 , 690 , 691 , 700 , 701 , 727 ) , 'muscle, skeletal' [SGK1 (human), homozygous knockout] ( 726 ) , 'muscle, smooth' ( 727 ) , 'neuron, cortical'-brain ( 661 ) , 'neuron, dorsal root ganglion'-brain ( 746 ) , 'neuron, hippocampal'-brain ( 661 ) , 'stem, embryonic' ( 200 , 366 ) , 'stem, mesenchymal' ( 20 ) , 'stem, prostate cancer' ( 31 ) , 1-LN (prostate cell) ( 196 ) , 1321N1 (glial) ( 881 ) , 201T ('epithelial, lung') ( 244 ) , 21T (breast cell) ( 365 ) , 22Rv1 (prostate cell) ( 503 ) , 293 (epithelial) ( 73 , 88 , 102 , 153 , 189 , 190 , 250 , 319 , 330 , 332 , 375 , 390 , 403 , 408 , 412 , 427 , 434 , 435 , 438 , 441 , 452 , 454 , 456 , 470 , 471 , 489 , 508 , 517 , 524 , 537 , 544 , 551 , 576 , 579 , 582 , 597 , 618 , 631 , 639 , 645 , 659 , 662 , 664 , 674 , 686 , 697 , 702 , 718 , 735 , 742 , 765 , 781 , 783 , 803 , 842 , 851 , 854 , 871 , 879 , 891 , 897 , 899 , 915 , 920 , 924 ) , 293 (epithelial) [ADRB2 (human), transfection] ( 491 ) , 293 (epithelial) [MDM2 (human)] ( 747 ) , 293 (epithelial) [Raptor (human), transfection] ( 293 ) , 293E (epithelial) ( 568 , 673 ) , 293T (epithelial) ( 51 , 62 , 93 , 95 , 185 , 294 , 296 , 365 , 429 , 437 , 470 , 478 , 562 , 566 , 568 , 571 , 577 , 675 , 693 , 694 , 709 , 773 , 862 , 863 , 880 ) , 2C4 (fibroblast) ( 873 ) , 2fTGH (fibroblast) ( 873 ) , 32D (myeloid) ( 631 ) , 3T3 (fibroblast) ( 83 , 177 , 190 , 434 , 481 , 521 , 538 , 657 , 662 , 840 , 921 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 767 , 768 , 781 , 815 , 837 , 866 , 876 ) , 3T3 (fibroblast) [Src (human)] ( 606 ) , 3T3-L1 (fibroblast) ( 171 , 547 , 572 , 714 ) , 41M (ovarian) ( 588 ) , 769P (renal) ( 6 , 811 ) , 786-O (renal) ( 6 , 178 ) , A172 (glial) ( 106 , 586 , 678 ) , A2780 (ovarian) ( 541 , 751 ) , A293T ('renal, embryonic') ( 562 ) , A375 (melanocyte) ( 61 , 207 , 425 , 621 , 627 ) , A427 (pulmonary) ( 15 ) , A431 (epithelial) ( 54 , 350 , 549 , 699 , 718 ) , A498 (renal) ( 811 ) , A549 (pulmonary) ( 15 , 17 , 24 , 52 , 54 , 75 , 81 , 85 , 115 , 116 , 187 , 194 , 212 , 244 , 270 , 328 , 341 , 362 , 406 , 412 , 436 , 454 , 455 , 467 , 485 , 488 , 527 , 538 , 583 , 630 , 636 , 672 , 699 , 709 , 758 , 771 ) , A549 (pulmonary) [SRXN1 (human), transfection] ( 495 ) , ACE (endothelial) ( 830 ) , ACHN (renal) ( 811 ) , ACN ( 80 ) , adipocyte-adipose tissue ( 45 , 703 ) , adipose tissue ( 72 , 559 ) , AGS (gastric) ( 139 , 458 , 525 ) , AGS (gastric) [CCKBR (human), transfection] ( 419 ) , AML10 (myeloid) ( 46 ) , AML11 (myeloid) ( 46 ) , AR42J (pancreatic) ( 612 ) , artery-heart ( 632 ) , Aspc1 (pancreatic) ( 11 , 69 , 74 , 735 ) , astrocyte ( 123 ) , astrocyte [p16-INK4A (human), homozygous knockout] ( 190 ) , astrocyte-'brain, striatum' ( 805 ) , AT52RM (lymphoblastoid) ( 320 ) , AU565 (breast cell) ( 580 ) , B lymphocyte ( 592 , 828 ) , B lymphocyte-spleen ( 582 ) , BAEC (endothelial) ( 489 , 565 , 573 , 575 , 618 , 683 , 732 , 780 , 786 , 796 , 817 , 864 , 887 , 892 ) , BaF3 ('B lymphocyte, precursor') ( 43 , 62 , 315 ) , BaF3 ('B lymphocyte, precursor') [EGFR (human)] ( 606 ) , BC3 (B lymphocyte) ( 131 ) , BE (melanocyte) ( 738 ) , BEAS-2B (epithelial) ( 57 , 631 ) , BEL7402 (hepatic) ( 35 ) , Ben-Men-1 ( 928 ) , BeWo ( 443 ) , BeWo31 ( 443 ) , BG-1 ( 372 ) , BHK (fibroblast) [HRas (human)] ( 556 ) , BHK (fibroblast) [KRas (human)] ( 556 ) , BHK (fibroblast) [Sin1 (human)] ( 556 ) , BJ (fibroblast) ( 596 ) , blood ( 140 ) , Bon1 (pancreatic) ( 29 ) , bone marrow ( 167 , 763 ) , BPH-1 (epithelial) ( 332 ) , brain ( 585 ) , breast ( 418 , 677 ) , breast cell-breast ( 838 ) , BT-474 (breast cell) ( 10 , 39 , 149 , 173 , 287 , 365 , 555 , 580 , 694 , 719 , 849 ) , BT-549 (breast cell) ( 172 , 173 , 369 , 657 ) , BxPC-3 (pancreatic) ( 735 ) , C2C12 (myoblast) ( 40 , 666 , 727 , 787 ) , C2C12 (myoblast) [SPRY2 (human), transfection] ( 666 ) , C33-A (cervical) ( 722 ) , C4-2 (prostate cell) ( 424 ) , Caco-2 (intestinal) ( 627 ) , Caki-1 (renal) ( 468 , 811 ) , Calu-1 (squamous) ( 436 , 538 ) , CAMA-1 (breast cell) ( 37 ) , Caov-3 (ovarian) ( 588 ) , Capan1 (pancreatic) ( 55 , 735 ) , Capan2 (pancreatic) ( 64 ) , CCRF-CEM (T lymphocyte) ( 235 ) , CD18/HPAF (pancreatic) ( 55 ) , CEF ( 13 ) , CEM (T lymphocyte) ( 543 ) , CFPAC-1 (pancreatic) ( 561 ) , CH27 (squamous) ( 866 ) , CHL (fibroblast) ( 885 ) , CHO (fibroblast) ( 36 , 374 , 547 , 662 , 729 ) , CHO (fibroblast) [EphB1 (human), transfection] ( 815 , 920 ) , CHO (fibroblast) [EPOR (human)] ( 576 ) , CHO (fibroblast) [INSR (human), transfection] ( 900 ) , CHO (fibroblast) [MAS1 (human)] ( 590 ) , chondrocyte ( 420 ) , CL1-0 (pulmonary) ( 116 , 194 ) , CL1-5 (pulmonary) ( 52 ) , COLO-357 (pancreatic) ( 365 ) , colon ( 77 ) , COS (fibroblast) ( 481 , 490 , 562 , 565 , 612 , 652 , 683 , 689 , 721 , 746 , 767 , 812 , 826 , 831 , 834 , 839 , 862 , 871 , 882 , 891 , 892 , 894 , 901 , 903 , 916 , 923 ) , CTL-EN (T lymphocyte) ( 775 ) , D425 ( 100 ) , Daoy ( 415 ) , DDT1-MF2 (myoblast) ( 861 ) , DF1 (fibroblast) ( 584 ) , DLBCL (B lymphocyte) ( 12 ) , DLD1 (intestinal) ( 4 , 248 , 407 , 500 , 657 , 679 ) , DM4 (melanocyte) ( 425 ) , DT40 (B lymphocyte) ( 592 ) , DU 145 (prostate cell) ( 196 , 450 , 462 , 469 , 549 , 789 , 856 , 877 , 914 ) , EA.hy 926 (endothelial) ( 870 , 904 ) , embryo ( 584 ) , endothelial-aorta ( 736 , 812 , 823 , 889 , 898 ) , endothelial-pulmonary artery ( 777 ) , endothelial-vein ( 741 , 832 , 890 ) , eosinophil ( 791 ) , epithelial ( 496 ) , epithelial-'kidney, tubule, proximal' ( 589 ) , epithelial-lens ( 326 ) , epithelial-prostate ( 642 ) , erythroblast ( 911 ) , ES (stem) ( 896 ) , ES2 (ovarian) ( 338 ) , ESC ( 449 ) , FaDu (squamous) ( 193 ) , Fao (hepatic) ( 547 ) , fibroblast ( 487 ) , fibroblast-embryo ( 426 ) , fibroblast-foreskin ( 138 , 771 ) , fibroblast-skin ( 724 ) , FL5.12 (lymphoid) ( 521 ) , Flow2000 ( 91 ) , GBM39 (astrocyte) ( 190 ) , GI-101A (breast cell) ( 776 , 843 ) , GIST544 (gastric) ( 761 ) , GIST882 (gastric) ( 761 ) , glial ( 41 ) , GM0637 (fibroblast) ( 712 ) , GM07078 (lymphoblastoid) ( 320 ) , GM08391 (fibroblast) ( 712 ) , GM09607 (fibroblast) ( 712 ) , GP293 (fibroblast) ( 62 ) , GRANTA-519 (B lymphocyte) ( 25 ) , GTL-16 (gastric) ( 406 ) , H19-7 (neuron) [IGF1R (human)] ( 678 ) , HaCaT (keratinocyte) ( 38 , 382 , 766 , 808 , 883 ) , HAEC (endothelial) ( 515 , 573 , 590 , 616 , 625 , 644 , 799 ) , HAK-1A (hepatic) ( 44 ) , HAK-1B (hepatic) ( 44 ) , HBEC3 (epithelial) ( 350 , 562 ) , HBL-100 (breast cell) ( 173 ) , HCC1806 (breast cell) ( 141 ) , HCC1937 (breast cell) ( 531 ) , HCC827 (pulmonary) ( 115 ) , HCCLM3 (hepatic) ( 76 ) , HCN-2 ('neuron, cortical') ( 433 ) , HCT116 (intestinal) ( 4 , 47 , 54 , 66 , 77 , 163 , 328 , 407 , 467 , 469 , 488 , 500 , 509 , 679 , 836 ) , HCT15 (intestinal) ( 142 ) , HDMEC (endothelial) ( 284 ) , heart ( 472 ) , HEI-193 (Schwann) ( 368 , 928 ) , HEL (erythroid) ( 487 ) , HeLa (cervical) ( 23 , 50 , 54 , 83 , 134 , 138 , 143 , 206 , 225 , 245 , 260 , 264 , 328 , 330 , 359 , 362 , 369 , 396 , 398 , 450 , 469 , 547 , 549 , 561 , 568 , 576 , 608 , 675 , 709 , 718 , 726 , 748 , 770 , 782 , 807 , 813 , 848 , 853 , 873 ) , HeLa S3 (cervical) ( 506 , 840 ) , hematopoietic progenitor-bone marrow ( 587 ) , hepatocyte ( 422 ) , hepatocyte-liver ( 9 , 691 , 772 ) , HepG2 (hepatic) ( 33 , 35 , 83 , 140 , 267 , 283 , 399 , 422 , 514 , 526 , 572 , 583 , 593 , 603 , 608 , 670 , 701 , 704 , 734 , 801 , 855 ) , HEY (ovarian) ( 119 , 338 , 776 , 843 ) , HFF1 (fibroblast) ( 27 ) , HGS-396 ( 286 ) , HGS-446 ( 286 ) , HL-7702 (hepatic) ( 169 ) , HL60 (myeloid) ( 104 , 797 , 819 , 878 ) , HMEC (endothelial) ( 92 , 365 , 486 , 762 ) , HMVEC (endothelial) ( 669 , 833 ) , HN5 (squamous) ( 380 , 695 ) , HPAC (pancreatic) ( 71 ) , HPB-ALL (T lymphocyte) ( 809 ) , HPCA (prostate cell) ( 739 ) , HS294T (melanocyte) ( 425 ) , HSC (squamous) ( 400 ) , HT-29 (intestinal) ( 295 , 484 , 509 , 568 , 693 , 709 , 723 , 847 ) , HT1080 (fibroblast) ( 103 , 286 , 328 , 498 , 500 , 862 , 895 ) , HUES-1 ('stem, embryonic') ( 22 ) , HUES-7 ('stem, embryonic') ( 22 ) , HUES-9 ('stem, embryonic') ( 22 ) , Huh7 (hepatic) ( 135 , 514 , 639 ) , HUT-78 (T lymphocyte) ( 383 , 620 ) , HUVEC (endothelial) ( 78 , 121 , 122 , 339 , 401 , 464 , 471 , 477 , 480 , 500 , 506 , 574 , 594 , 601 , 616 , 628 , 660 , 669 , 683 , 729 , 760 , 771 , 778 , 779 , 788 , 822 , 858 , 869 , 875 , 876 , 878 , 882 , 904 , 905 , 907 , 925 ) , HUVEC (endothelial) [IRS1 (human)] ( 778 ) , IGROV1 (ovarian) ( 388 , 810 ) , IMR-90 (fibroblast) ( 4 , 194 , 596 ) , IMR32 (neural crest) ( 585 ) , IOSE-29 (ovarian) ( 810 ) , IR938F (B lymphocyte) ( 816 ) , Ishikawa (endometrial) ( 428 ) , JAR (placental) ( 306 ) , JB (epithelial) ( 682 ) , JEKO-1 (B lymphocyte) ( 25 ) , Jurkat (T lymphocyte) ( 1 , 164 , 202 , 289 , 290 , 291 , 292 , 329 , 336 , 337 , 370 , 371 , 383 , 402 , 411 , 543 , 569 , 578 , 620 , 680 , 730 , 737 , 744 , 809 , 816 , 852 , 866 , 909 ) , K562 (erythroid) ( 58 , 62 , 389 , 417 , 692 ) , Karpas-299 (T lymphocyte) ( 281 , 373 ) , Kasumi-1 (myeloid) ( 378 ) , KATO III (gastric) ( 406 , 432 ) , KCL22 (myeloid) ( 58 ) , KELLY (neural crest) ( 585 ) , keratinocyte ( 9 , 848 ) , keratinocyte-skin ( 795 ) , KG-1 (myeloid) ( 643 ) , kidney ( 427 , 468 ) , KLE (endometrial) ( 8 ) , KM-H2 (lymphoid) ( 725 ) , Ku-19-20 (renal) ( 811 ) , Kyse450 (squamous) ( 651 ) , L02 (hepatic) ( 117 , 228 ) , L1236 (lymphoid) ( 725 ) , L3.6p1 (pancreatic) ( 55 ) , L540 (lymphoid) ( 384 ) , L6 (myoblast) ( 547 , 667 , 846 , 924 ) , LAN-1 (neural crest) ( 479 ) , LCL (lymphoblastoid) ( 320 ) , Leio-177 ( 286 ) , liver ( 507 , 583 , 701 , 714 ) , LLC-PK1 (epithelial) ( 564 , 919 ) , LN-Z308 (glial) ( 602 ) , LN229 (glial) ( 41 , 48 , 258 , 348 , 647 ) , LNCaP (prostate cell) ( 90 , 97 , 197 , 254 , 270 , 308 , 343 , 414 , 460 , 469 , 503 , 536 , 615 , 623 , 629 , 747 , 757 , 765 , 811 , 910 , 914 , 927 ) , lung ( 60 , 376 , 377 , 413 , 446 , 630 ) , lymphocyte-blood ( 7 , 18 , 852 ) , M059J (glial) ( 452 , 548 ) , M14-MEL (melanocyte) ( 649 ) , macrophage-blood ( 721 ) , macrophage-bone marrow ( 42 ) , mammary gland ( 657 ) , mast-bone marrow ( 582 ) , MCF-10A (breast cell) ( 89 , 93 , 168 , 247 , 295 , 369 , 469 , 497 , 631 , 657 , 673 , 769 , 818 , 843 ) , MCF-10A (breast cell) [GAB2 (human), transfection] ( 490 ) , MCF-7 (breast cell) ( 10 , 26 , 138 , 149 , 159 , 173 , 208 , 251 , 253 , 255 , 272 , 280 , 335 , 342 , 372 , 374 , 405 , 410 , 412 , 416 , 418 , 427 , 431 , 440 , 450 , 451 , 460 , 476 , 486 , 504 , 512 , 549 , 550 , 561 , 571 , 600 , 603 , 611 , 613 , 624 , 638 , 643 , 654 , 673 , 699 , 702 , 710 , 731 , 742 , 745 , 773 , 800 , 844 , 867 , 901 ) , MCF-7 (breast cell) [Akt1 (human)] ( 638 ) , MCF-7 (breast cell) [CYP19A1 (human)] ( 688 ) , MCF-7 (breast cell) [EGFR (human)] ( 638 ) , MCF-7 (breast cell) [MEK1 (human)] ( 638 ) , MCF-7 (breast cell) [Src (human)] ( 622 ) , MCF10A1 (epithelial) ( 49 , 172 , 255 ) , MDA-MB-231 (breast cell) ( 9 , 10 , 39 , 51 , 79 , 143 , 172 , 173 , 229 , 247 , 270 , 295 , 299 , 372 , 445 , 448 , 454 , 476 , 502 , 512 , 531 , 657 , 677 , 731 , 867 ) , MDA-MB-361 (breast cell) ( 173 , 367 , 849 ) , MDA-MB-435 (breast cell) ( 173 , 216 , 362 , 561 , 657 , 867 ) , MDA-MB-453 (breast cell) ( 173 , 469 , 561 , 849 ) , MDA-MB-468 (breast cell) ( 172 , 173 , 391 , 448 , 454 , 460 , 469 , 506 , 531 , 580 , 657 , 753 ) , MDAH2774 (ovarian) ( 561 ) , MDCK (epithelial) ( 853 , 857 ) , ME-180 (cervical) ( 380 ) , MEF (fibroblast) ( 73 , 83 , 138 , 161 , 264 , 403 , 437 , 452 , 537 , 538 , 548 , 568 , 657 ) , MEF (fibroblast) [BRCA1 (mouse), transgenic] ( 253 ) , MEF (fibroblast) [Etk (human), heterozygous knockout] ( 182 ) , MEF (fibroblast) [IGF1R (mouse)] ( 776 ) , MEF (fibroblast) [Myc (mouse)] ( 649 ) , MEF (fibroblast) [p70S6K (mouse), homozygous knockout] ( 366 ) , MEF (fibroblast) [RICTOR (human), homozygous knockout] ( 330 ) , MEF (fibroblast) [TSC22D2 (human)] ( 549 ) , MEL624 (melanocyte) ( 425 ) , melanocyte-skin [IKKB (mouse), homozygous knockout] ( 351 ) , mesangial ( 619 , 717 ) , mesenchymal ( 60 ) , MeWo (melanocyte) ( 425 , 621 ) , MFH-841 ( 286 ) , MFH-M ( 286 ) , MG63 (bone cell) ( 367 ) , MHCC97-L (hepatic) ( 76 ) , MIA PaCa (pancreatic) ( 549 ) , MIA PaCa-2 (pancreatic) ( 71 , 467 , 735 ) , microvessel endothelial ( 349 ) , MIN6 (pancreatic) ( 522 ) , MKN-45 (gastric) ( 195 , 317 , 318 , 321 , 344 , 346 , 347 , 354 , 355 , 387 , 392 , 393 , 394 , 525 ) , MKN-74 (gastric) ( 458 ) , ML-1 (myeloid) ( 614 ) , Mo7e (myeloid) ( 764 ) , MOLT-4 (T lymphocyte) ( 620 ) , mononuclear ( 430 , 599 ) , MPNST724 ( 286 ) , MRC5 (fibroblast) ( 81 , 500 ) , MSN (neuron) ( 752 ) , MTSV (epithelial) ( 707 ) , muscle ( 671 ) , Mv1Lu (epithelial) ( 668 ) , MV4-11 (macrophage) ( 43 , 46 ) , myeloid ( 749 ) , myeloid-bone marrow ( 516 ) , myoblast ( 563 ) , myocyte-heart ( 640 , 655 , 790 , 884 ) , Namalwa (B lymphocyte) ( 592 ) , NB-4 (myeloid) ( 643 , 710 ) , NBS-ILB1 (fibroblast) ( 320 ) , NCI-H1299 (pulmonary) ( 66 , 115 , 194 , 436 , 488 , 636 ) , NCI-H157 (pulmonary) ( 66 , 436 , 450 , 538 , 693 ) , NCI-H1650 (pulmonary) ( 341 , 488 , 684 ) , NCI-H1666 (pulmonary) ( 630 ) , NCI-H1703 (squamous) ( 195 , 324 , 325 , 345 , 395 , 406 , 488 ) , NCI-H1781 (pulmonary) ( 631 ) , NCI-H1792 (pulmonary) ( 656 ) , NCI-H1819 (pulmonary) ( 350 ) , NCI-H1838 (pulmonary) ( 656 ) , NCI-H1975 (pulmonary) ( 24 , 133 , 187 , 341 , 684 ) , NCI-H23 (pulmonary) ( 194 , 488 ) , NCI-H292 (pulmonary) ( 187 , 241 , 287 ) , NCI-H3255 (pulmonary) ( 187 , 195 , 322 , 323 ) , NCI-H345 (pulmonary) ( 728 ) , NCI-H441 (pulmonary) ( 352 , 353 , 356 , 357 , 358 ) , NCI-H460 (pulmonary) ( 15 , 24 , 115 , 187 , 436 , 488 , 549 ) , NCI-H510 (pulmonary) ( 728 ) , NCI-H69 (pulmonary) ( 728 ) , NCI-H727 (epithelial) ( 29 ) , NCI-H929 (B lymphocyte) ( 63 ) , neuron-'brain, cerebellum' ( 756 ) , neuron-'brain, hippocampus' ( 239 , 825 ) , neutrophil ( 552 , 558 , 794 , 878 , 897 ) , NL-17 (intestinal) ( 862 ) , NMuMG (epithelial) ( 181 ) , NSCLC (pulmonary) ( 886 ) , OAW28 (ovarian) ( 30 ) , OCI/AML3 (myeloid) ( 46 ) , OK (renal) ( 546 , 598 ) , oocyte ( 68 , 222 ) , osteoblast-calvarium ( 633 , 720 ) , ovarian ( 591 ) , ovary ( 361 , 474 , 754 ) , OvCa433 ( 120 ) , OVCAR3 (ovarian) ( 30 , 388 , 560 , 561 , 751 ) , OVCAR4 (ovarian) ( 588 , 754 ) , OVCAR5 (ovarian) ( 388 , 588 , 754 ) , P116 (T lymphocyte) ( 383 ) , PAE (endothelial) ( 73 , 331 , 363 , 482 , 676 , 705 , 882 , 902 ) , PANC-1 (pancreatic) ( 69 , 71 , 365 , 467 , 687 ) , pancreas ( 69 , 711 , 735 , 740 ) , pancreatic ( 263 ) , pancreatic acini ( 626 ) , PC-12 (chromaffin) ( 167 , 678 , 756 , 826 , 839 ) , PC3 (prostate cell) ( 14 , 41 , 83 , 90 , 97 , 196 , 205 , 234 , 270 , 295 , 424 , 461 , 462 , 463 , 469 , 512 , 549 , 642 , 653 , 709 , 715 , 789 , 841 , 862 , 877 , 914 ) , PC3 (prostate cell) [CD82 (human)] ( 642 ) , PC9-IR (pulmonary) ( 133 ) , PEO4 (ovarian) ( 588 ) , PEO6 (ovarian) ( 588 ) , platelet-blood ( 127 , 444 , 501 , 532 , 581 , 774 , 860 , 906 ) , PLC/PRF/5 (hepatic) ( 117 ) , prostate ( 496 , 750 ) , QGP-1 (endocrine) ( 29 ) , QZG (hepatic) ( 228 ) , Rat1 (fibroblast) ( 548 ) , RAW 264.7 (macrophage) ( 294 ) , RCC4 (renal) ( 468 ) , RD (muscle cell) ( 40 , 155 ) , Rh1 (bone cell) ( 518 ) , Rh13 (muscle cell) ( 787 ) , Rh18 (muscle cell) ( 518 , 787 ) , Rh30 (muscle cell) ( 40 , 155 , 518 , 542 , 787 ) , Rh4 (muscle cell) ( 787 ) , Rh41 ( 518 ) , Rh5 (muscle cell) ( 787 ) , RMF (fibroblast) ( 27 ) , RPMI-8226 (plasma cell) ( 16 ) , RPTE (epithelial) ( 811 ) , RWP1 (pancreatic) ( 189 ) , RWPE1 (prostate cell) ( 418 ) , Saos-2 (bone cell) ( 659 ) , SB2 (melanocyte) ( 425 ) , SCC12 (keratinocyte) ( 868 ) , Schwann ( 478 ) , SF767 (glial) ( 32 ) , SGC7901 (gastric) ( 148 ) , SH-SY5Y (neural crest) ( 246 , 259 , 277 , 513 , 537 , 585 , 604 , 641 , 678 , 756 , 783 , 825 , 827 , 850 , 872 , 874 ) , SHEP (neuron) ( 585 , 752 , 926 ) , SK-LMS-1 (muscle cell) ( 286 ) , SK-MEL-23 (melanocyte) ( 434 ) , SK-MEL2 (melanocyte) ( 425 ) , SK-MEL28 (melanocyte) ( 70 ) , SK-MEL5 (melanocyte) ( 425 ) , SK-N-MC (neural crest) ( 118 , 752 ) , SKBr3 (breast cell) ( 34 , 39 , 173 , 287 , 369 , 386 , 454 , 502 , 505 , 561 , 719 , 785 , 849 ) , SKBR7 (breast cell) ( 51 ) , skin ( 38 , 425 , 820 ) , SKNBE (neural crest) ( 585 ) , SKNSH (neural crest) ( 585 ) , SKOV-3 (ovarian) ( 53 , 67 , 149 , 295 , 338 , 368 , 388 , 588 , 591 , 665 , 754 , 810 , 834 , 865 ) , SKRC-44 (renal) ( 658 , 811 ) , SKRC-49 (renal) ( 811 ) , SN12C (renal) ( 174 ) , SNB-19 (glial) ( 647 , 663 ) , SNU-1 (gastric) ( 525 ) , SNU-484 (gastric) ( 511 ) , SNU-620 (gastric) ( 511 ) , SNU16Ad (gastric) ( 458 ) , SR-786 (T lymphocyte) ( 373 ) , SRB-1 (squamous) ( 808 ) , ST88-14 (neuron) ( 404 ) , SU-DHL1 (T lymphocyte) ( 373 ) , Su.86.86 (pancreatic) ( 19 , 69 ) , SUM159 (breast cell) ( 531 ) , SUP-M2 (T lymphocyte) ( 281 ) , SV40 ( 669 ) , SW-1573 (pulmonary) ( 187 , 527 ) , SW1353 ( 82 ) , SW1990 (pancreatic) ( 71 ) , SW48 (intestinal) ( 142 , 723 ) , SW480 (intestinal) ( 657 ) , SW620 (intestinal) ( 142 , 557 ) , SW684 ( 286 ) , SY5Y (neuron) ( 755 , 784 ) , synoviocyte-synovium ( 519 ) , T lymphocyte ( 59 ) , T lymphocyte-blood ( 261 , 519 , 545 , 554 , 570 , 595 , 814 ) , T/C-28a2 (chondrocyte) ( 340 ) , T24 (bladder cell) ( 278 , 500 , 624 ) , T47D (breast cell) ( 26 , 37 , 138 , 173 , 307 , 333 , 381 , 386 , 451 , 505 , 561 , 776 , 917 ) , T98G (glial) ( 138 , 258 , 313 , 609 , 759 , 873 ) , TF-1 (erythroid) ( 102 , 643 , 913 ) , THP1 (myeloid) ( 475 , 533 ) , thymus ( 314 ) , thyroid ( 706 , 826 ) , TPC-1 (thyroid cell) ( 706 ) , Tsu (prostate cell) ( 856 ) , U-118MG (glial) ( 32 ) , U-937 (myeloid) ( 465 , 528 , 643 , 749 , 809 ) , U251 (glial) ( 32 , 313 , 602 , 647 , 648 , 663 ) , U2OS (bone cell) ( 158 , 177 , 412 , 447 , 460 , 584 ) , U2OS (bone cell) [GR (human)] ( 696 ) , U373 MG (glial) ( 379 , 441 , 647 ) , U4A (fibroblast) ( 873 ) , U87MG (glial) ( 32 , 106 , 274 , 300 , 365 , 412 , 585 , 586 , 647 , 648 , 663 , 685 , 733 , 747 , 859 , 896 , 908 ) , U87MG (glial) [EGFR (human), transfection] ( 348 ) , UACC-257 (melanocyte) ( 425 ) , UCSD-354L (melanocyte) ( 425 ) , UI.wt (fibroblast) ( 835 ) , UMSCC1 (squamous) ( 193 , 312 ) , UMSCC11A (squamous) ( 312 ) , UMSCC11A (squamous) [YAP1 (human), transfection] ( 312 ) , UMSCC11B (squamous) ( 312 ) , UMSCC22A (squamous) ( 312 ) , UMSCC22B (squamous) ( 312 ) , UMSCC38 (squamous) ( 312 ) , UMSCC46 (squamous) ( 312 ) , UMSCC6 (squamous) ( 312 ) , UMSCC9 (squamous) ( 312 ) , UT-7 (myeloid) ( 191 , 510 ) , UT-7 (myeloid) [EPO (human), transfection] ( 911 ) , vascular smooth muscle cell ('muscle, smooth') ( 534 , 657 ) , VSMC ('muscle, smooth') ( 166 ) , VSMC-aorta ( 327 ) , WI-38 (fibroblast) ( 460 ) , WiDr (epithelial) ( 47 ) , WM-1552 (melanocyte) ( 425 ) , WM115 (melanocyte) ( 820 ) , WM1799 (melanocyte) ( 425 ) , WM2664 (melanocyte) ( 425 ) , WM3211 (melanocyte) ( 425 ) , WM35 (melanocyte) ( 425 , 504 , 621 ) , WM46 (melanocyte) ( 425 ) , WM793 ( 295 ) , ZR-75-1 (breast cell) ( 37 , 173 , 603 )

Upstream Regulation
Regulatory protein:
4E-BP1 (human) ( 508 ) , Ack (human) ( 76 , 418 ) , ACPP (human) ( 343 ) , AFAP1L2 (human) ( 457 ) , AFP (human) ( 117 ) , Akt1 (human) ( 4 , 113 , 222 , 254 , 277 , 295 , 480 , 481 , 520 , 583 , 638 , 811 , 849 , 851 , 852 , 908 ) , Akt2 (human) ( 132 , 254 , 481 ) , ALK (human) ( 859 ) , AMIGO2 (human) ( 78 ) , AMPKA1 (human) ( 342 , 594 ) , AMPKA2 (human) ( 676 ) , AR (human) ( 254 ) , ARAF (human) ( 596 ) , ATM (human) ( 712 ) , ATP6V1B2 (mouse) ( 597 ) , AurA (human) ( 458 ) , axin 1 (mouse) ( 239 ) , Bcr (human) ( 12 ) , beclin 1 (human) ( 79 ) , BMF (human) ( 207 ) , BRAF (human) ( 425 ) , Brk (human) ( 332 ) , BTG2 (human) ( 247 ) , Btk (human) ( 592 ) , CA9 (human) ( 658 ) , CAMKK1 (human) ( 851 ) , caveolin-1 (human) ( 155 ) , CCKBR (human) ( 612 ) , CD10 (human) ( 319 ) , CD133 (human) ( 95 ) , CD82 (human) ( 642 ) , CDC25B (human) ( 450 ) , CDC37 (human) ( 110 ) , CDK1 (human) ( 22 ) , CDK5 (human) ( 90 , 119 ) , CHKA (human) ( 476 ) , CHKB (human) ( 476 ) , CK1E (human) ( 153 ) , CPNE3 (human) ( 386 ) , CSF2RB (human) ( 775 ) , CXCR4 (human) ( 115 ) , CYP3A5 (human) ( 96 ) , CYR61 (human) ( 379 ) , DARPP-32 (human) ( 525 ) , DDIT4 (human) ( 697 ) , DDIT4L (human) ( 697 ) , DDX5 (human) ( 77 ) , DOK2 (human) ( 689 ) , DYRK2 (human) ( 26 ) , E4 (adenovirus) ( 771 ) , EFNA2 (human) ( 295 ) , EGFR (human) ( 446 , 456 , 630 , 638 ) , eNOS (mouse) ( 480 ) , Epac1 (human) ( 196 , 491 ) , Epiregulin (human) ( 247 ) , EPOR (human) ( 191 ) , ER-alpha (human) ( 250 , 374 ) , ER-beta (human) ( 577 ) , ERK1 (human) ( 574 , 576 ) , ERK2 (human) ( 574 , 576 ) , ERK5 (human) ( 363 ) , Etk (human) ( 182 ) , FAK (human) ( 557 ) , FHIT (human) ( 636 ) , FKBP5 (human) ( 8 , 254 ) , FOXO1A (human) ( 375 ) , FOXO3A (human) ( 173 ) , FRK (human) ( 447 ) , FRS2 (human) ( 613 ) , FSTL1 (mouse) ( 480 ) , G-alpha(q) (human) ( 475 ) , GAB2 (human) ( 490 ) , GAS6 (human) ( 18 ) , GHSR (human) ( 573 ) , girdin (human) ( 56 ) , GRB14 (human) ( 639 ) , GRB2 (human) ( 279 , 660 ) , GSK3B (human) ( 141 ) , HER2 (human) ( 173 , 630 , 631 ) , HIF2A (human) ( 427 ) , HRas (human) ( 4 , 247 , 295 , 362 , 467 , 716 ) , HSP70 (human) ( 92 ) , HSP90A (human) ( 502 ) , IEX-1 (human) ( 576 ) , IGFBP3 (human) ( 436 ) , IKKB (human) ( 499 ) , IKKB (mouse) ( 351 ) , IL2RA (human) ( 570 ) , ILK (human) ( 362 , 512 , 648 , 657 , 687 , 765 , 779 , 782 , 914 ) , ILKAP (human) ( 888 ) , INPP4B (human) ( 47 ) , INPP5E (human) ( 863 ) , IRS1 (human) ( 778 ) , ITGA3 (human) ( 75 ) , JNK1 (human) ( 574 ) , JNK2 (human) ( 574 ) , KRas (human) ( 311 , 716 ) , LAPTM4B (human) ( 97 ) , Lck (human) ( 792 ) , LIMS1 (human) ( 782 ) , LKB1 (human) ( 488 , 506 ) , LKB1 (mouse) ( 68 ) , Lmr3 (human) ( 251 ) , LYN (human) ( 516 ) , MEK1 (human) ( 546 , 665 , 843 ) , Mer (mouse) ( 517 ) , MINK (human) ( 51 ) , MKK4 (human) ( 655 ) , MKK6 (human) ( 683 , 843 ) , MST2 (human) ( 368 ) , mTOR (human) ( 96 , 222 , 362 , 438 , 454 , 476 , 512 , 515 , 549 , 582 ) , MUC4 (human) ( 627 ) , MYO6 (human) ( 17 ) , N-WASP (human) ( 17 ) , NCK1 (mouse) ( 162 ) , NCK2 (mouse) ( 162 ) , NDFIP1 (human) ( 359 ) , NDFIP2 (human) ( 359 ) , NF1 (human) ( 596 ) , Notch 1 (human) ( 73 , 637 ) , NRas (human) ( 311 , 425 ) , NRG1 (human) ( 247 , 388 ) , OSBPL8 (mouse) ( 267 ) , OSBPL9 (human) ( 582 ) , p16-INK4A (human) ( 109 ) , P2X7 (human) ( 80 ) , P38A (human) ( 683 , 843 ) , p53 (human) ( 460 , 637 ) , PAK1 (rat) ( 481 ) , PAK2 (human) ( 481 ) , PARVA (human) ( 116 ) , PARVB (human) ( 731 ) , PBK (human) ( 194 ) , PCGF2 (human) ( 505 ) , PDE4B (human) ( 491 ) , PDE4D (human) ( 491 ) , PDK1 (human) ( 716 , 842 ) , PDK1 (mouse) ( 900 ) , PDZK1 (human) ( 6 ) , PEAK1 (human) ( 172 ) , PHLDA3 (human) ( 460 ) , PHLPP (human) ( 295 , 365 , 567 ) , PHLPP2 (human) ( 365 , 567 ) , PI5PA (mouse) ( 652 ) , PIK3C2A (human) ( 53 , 470 , 474 ) , PIK3C2B (human) ( 235 ) , PIK3CA (human) ( 295 , 418 , 497 , 599 , 843 ) , PIK3CB (human) ( 362 ) , PIK3CD (human) ( 538 ) , PIK3CG (human) ( 746 ) , PIK3R1 (human) ( 14 , 665 ) , PIK3R2 (human) ( 13 ) , Pim1 (human) ( 48 , 462 ) , PINK1 (human) ( 271 ) , PKCA (human) ( 329 , 428 ) , PKCB (human) ( 599 ) , PKCE (human) ( 334 ) , PKCT (human) ( 178 ) , PKN1 (human) ( 900 ) , PKN2 (human) ( 900 , 903 ) , PKR (human) ( 498 ) , PLCG2 (human) ( 592 ) , PPM1D (human) ( 100 ) , PPP1CA (human) ( 326 ) , PPP2CA (human) ( 398 , 521 ) , PPP2R2A (human) ( 55 , 57 ) , PPP2R5B (human) ( 576 ) , PPP2R5D (human) ( 576 ) , PRAS40 iso3 (human) ( 508 ) , PREX1 (human) ( 307 ) , PRICKLE1 (human) ( 51 ) , PRKD1 (human) ( 99 ) , PTEN (human) ( 168 , 190 , 311 , 474 , 506 , 578 , 580 , 584 , 792 , 852 , 896 , 908 , 909 , 914 ) , PTEN (mouse) ( 896 ) , PTGER2 (mouse) ( 340 ) , PTGER3 (mouse) ( 340 ) , PTPRJ (human) ( 471 ) , PTPRK (human) ( 95 ) , PXN iso2 (human) ( 407 ) , Pyk2 (human) ( 605 ) , QIK (human) ( 338 ) , RAC1 (human) ( 57 , 481 ) , RAP1A (human) ( 464 , 491 ) , RAP1B (human) ( 464 ) , RAP2A (human) ( 491 ) , Raptor (human) ( 438 , 515 , 549 ) , Raptor (mouse) ( 404 ) , RARRES2 (human) ( 420 ) , RASGRP3 (human) ( 106 ) , RBP1 (human) ( 707 ) , reelin (human) ( 63 ) , Ret (human) ( 335 , 457 , 826 ) , RHOA (human) ( 843 ) , RHOB (human) ( 57 ) , RICTOR (human) ( 37 , 44 , 60 , 96 , 196 , 206 , 311 , 330 , 438 , 454 , 461 , 476 , 504 , 512 , 515 , 549 ) , S6 (human) ( 743 ) , SGK1 (human) ( 726 ) , SHC3 (human) ( 839 ) , SHIP (human) ( 261 , 737 ) , SHIP-2 (mouse) ( 908 ) , SHP-1 (human) ( 792 ) , SHP-2 (human) ( 295 ) , SHPS1 (human) ( 348 ) , Sin1 (human) ( 454 ) , Sin1 (mouse) ( 161 ) , SLC1A5 (human) ( 553 ) , SMAD7 (human) ( 715 ) , Snail1 (human) ( 189 ) , SOCS3 (human) ( 526 ) , SPRY2 (human) ( 666 ) , Src (human) ( 190 , 471 , 520 , 622 , 624 , 665 , 792 ) , SRXN1 (human) ( 495 ) , ST3GAL5 (human) ( 104 ) , ST8SIA1 (human) ( 104 ) , STAT3 (mouse) ( 422 ) , Survivin (human) ( 410 ) , TACE (human) ( 630 ) , TBX2 (human) ( 40 ) , TNK1 (human) ( 384 ) , TRAF6 (human) ( 437 ) , TrkB (human) ( 827 ) , TSC2 (human) ( 504 ) , ULK1 (human) ( 566 ) , USP49 (human) ( 19 ) , VCAM1 (human) ( 229 ) , VEGFR1 (human) ( 902 ) , VEGFR2 (human) ( 902 ) , YAP1 (human) ( 91 ) , ZFP57 (human) ( 103 )
Putative in vivo kinases:
AXL (human) ( 36 ) , IKKE (human) ( 227 ) , ILK (human) ( 803 , 810 , 877 , 916 ) , LRRK2 (human) ( 246 ) , Mer (human) ( 36 ) , mTOR (human) ( 709 ) , PDK1 (human) ( 862 ) , PIKFYVE (human) ( 824 ) , PRKD1 (human) ( 842 ) , TBK1 (human) ( 276 )
Kinases, in vitro:
DNAPK (human) ( 452 ) , ILK (human) ( 877 ) , LRRK2 (human) ( 246 ) , MAPKAPK2 (human) ( 924 ) , mTOR (human) ( 138 , 161 , 206 , 216 , 316 , 362 , 709 ) , PDK1 (human) ( 862 ) , PKCA (human) ( 906 ) , PKCB (human) ( 906 ) , TBK1 (human) ( 294 )
Putative upstream phosphatases:
PHLPP (human) ( 693 ) , PHLPP2 (human) ( 567 ) , PPP1CA (human) ( 269 , 785 ) , PPP2CA (human) ( 445 )
Phosphatases, in vitro:
PHLPP (human) ( 693 ) , PHLPP2 (human) ( 567 ) , PPP1CA (human) ( 785 ) , PTEN (human) ( 30 )
Treatments:
1-azakenpaullone ( 141 ) , 1-methyladenine ( 222 ) , 14,15-DHETs ( 283 ) , 14,15-EETs ( 283 ) , 15-epi-LXA4 ( 552 ) , 17-beta-estradiol ( 148 ) , 2-AG ( 127 ) , 2-deoxyglucose ( 328 , 436 , 488 , 831 ) , 3-aminobenzamide ( 600 ) , 4-DAMP ( 197 , 881 ) , 4-HT ( 89 , 143 , 449 , 520 , 537 , 600 , 748 , 769 , 842 ) , 5(S)-HETE ( 833 ) , 5-cholesten-5-beta-ol ( 382 ) , 5-thio-glucose ( 831 ) , 6-MB-cAMP ( 135 ) , 6-OHDA ( 756 ) , 8-CPT-2Me-cAMP ( 196 ) , 8-Rp-cAMP ( 632 ) , A-443654 ( 479 , 549 , 557 , 598 ) , A-674563 ( 286 ) , A23187 ( 605 , 823 ) , A740003 ( 80 ) , acadesine ( 135 , 171 , 445 , 594 , 799 ) , actinomycin_D ( 366 ) , activin ( 200 ) , ADA ( 558 ) , adiponectin ( 445 , 786 ) , adriamycin ( 118 , 460 ) , AEE788 ( 341 , 386 ) , afatinib ( 133 ) , AG1024 ( 776 ) , AG1296 ( 776 ) , AG1478 ( 120 , 271 , 348 , 382 , 400 , 473 , 605 , 678 , 718 , 776 , 848 ) , AG2037 ( 15 ) , AG490 ( 510 , 526 , 833 ) , AH6809 ( 174 , 340 ) , Akt-I-1 ( 398 , 546 , 722 ) , Akt-I-1,2 ( 369 , 428 , 722 ) , Akt_inhibitor_VIII ( 277 , 333 , 372 , 458 ) , Akt_inhibitor_X ( 312 ) , aldosterone ( 628 ) , aloe-emodin ( 34 ) , alpelisib ( 29 , 48 ) , alpha-mangostin ( 299 ) , alphaIR3 ( 532 , 787 ) , amino_acid_starvation ( 134 , 621 ) , amino_acids ( 403 , 508 , 667 , 674 , 768 ) , aminoflavone ( 550 ) , anastrozole ( 374 ) , androsterone ( 374 ) , angiopoietin-1 ( 700 , 777 , 905 , 925 ) , angiopoietin-2 ( 700 , 905 ) , angiotensin ( 760 ) , angiotensin-(1-7) ( 590 ) , anisomycin ( 768 ) , anthrax_toxin ( 533 ) , anti-Akt1 ( 694 ) , anti-CD11a ( 595 ) , anti-CD150 ( 725 ) , anti-CD28 ( 595 ) , anti-CD3 ( 261 , 383 , 545 , 814 , 909 ) , anti-CD3/CD28 ( 570 , 730 ) , anti-CD44 ( 595 ) , anti-CD53 ( 816 ) , anti-CD8 ( 544 ) , anti-FcRII ( 897 ) , anti-FcRIII ( 897 ) , anti-HER2 ( 149 , 580 , 719 , 849 ) , anti-HLA ( 515 ) , anti-ICAM-2 ( 866 ) , anti-ICOS ( 595 ) , anti-IgD ( 162 ) , anti-IGF1R ( 436 ) , anti-IgM ( 162 , 599 ) , anti-integrin_alpha9beta1 ( 295 ) , anti-PDGFR ( 487 , 776 ) , anti-TCR ( 578 ) , anti-VE-cadherin ( 771 ) , anti-VEGF ( 780 ) , APC ( 465 ) , apelin ( 729 ) , apoA-I ( 764 ) , apocynin ( 74 ) , apyrase ( 532 ) , AR-A014418 ( 141 ) , arachidonic_acid ( 878 ) , ARC ( 523 ) , ARC69331-MX ( 532 ) , As2O3 ( 543 ) , atiprimod ( 593 ) , atorvastatin ( 594 , 869 ) , ATP ( 473 , 807 ) , atropine ( 881 ) , AZ1060120 ( 80 ) , AZD6094 ( 87 ) , AZD8055 ( 44 , 85 , 412 ) , BAPTA-AM ( 598 , 605 , 653 , 774 , 869 , 876 , 892 , 906 , 912 ) , BDNF ( 755 ) , bicyclol ( 33 ) , bisindolylmaleimide ( 506 , 532 , 582 , 599 , 906 ) , black_tea_polyphenols ( 683 ) , BN52021 ( 823 ) , BNTX ( 11 ) , Boc-D-FMK ( 804 ) , bombesin ( 626 ) , bortezomib ( 372 ) , BPDE ( 605 ) , bpV ( 785 ) , BQ ( 793 ) , BQ-123 ( 718 ) , BQ-788 ( 718 ) , bradykinin ( 882 , 887 , 892 ) , BRL37344 ( 640 ) , butaprost ( 174 ) , BzATP ( 80 ) , C2-ceramide ( 811 ) , C3_toxin ( 843 ) , C5a ( 763 ) , C5b-9 ( 625 ) , C6-ceramide ( 53 , 913 ) , Ca(2+) ( 841 , 912 ) , caffeine ( 274 , 277 ) , calpeptin ( 612 ) , calphostin_C ( 397 ) , calyculin_A ( 295 , 581 , 632 , 653 , 785 , 825 , 869 , 913 ) , cAMP_analog ( 478 , 491 , 698 ) , canertinib ( 513 ) , cangrelor ( 774 ) , carbachol ( 197 , 626 , 805 , 881 ) , carmustine ( 602 ) , CAY10399 ( 558 ) , Cbz-B3A ( 62 ) , CCCP ( 783 ) , CCL5 ( 455 ) , CDDO-Me ( 492 ) , celecoxib ( 847 ) , cell_adhesion ( 663 ) , ceramide ( 807 , 916 ) , CGS_21680 ( 558 ) , chelerythrine ( 397 ) , cholesterol_oxidase ( 382 ) , ciclosporin ( 258 , 653 , 678 , 732 , 825 ) , cisplatin ( 120 , 380 , 675 , 811 ) , CK37 ( 245 ) , CML ( 524 ) , colforsin ( 444 , 478 , 491 , 546 , 558 , 632 , 891 ) , collagen ( 642 , 860 ) , collagen XIX (NC1 domain) ( 70 ) , compound_7 ( 275 ) , compound_C ( 445 , 594 , 676 ) , conditioned medium ( 46 , 139 ) , convulxin ( 860 ) , coumermycin ( 902 ) , CPA ( 912 ) , crizotinib ( 244 , 281 ) , CRP ( 444 ) , CSD_peptide ( 869 ) , CTGF ( 619 , 717 ) , culturing_of_cells ( 599 , 740 ) , CV3988 ( 823 ) , CXCL12 ( 592 , 599 ) , cyclic_stretch ( 718 ) , cycloheximide ( 225 ) , D609 ( 807 ) , dactolisib ( 108 , 159 , 254 , 497 ) , DAMGO ( 920 ) , dasatinib ( 102 , 133 , 193 , 295 ) , decorin ( 870 ) , deoxygenation ( 150 ) , depolarization ( 604 , 678 ) , derivative-2 ( 131 ) , dexamethasone ( 543 , 564 , 720 ) , DHC ( 916 ) , DHPG ( 579 ) , dimethylfumarate ( 121 ) , DMNQ ( 793 ) , DMS ( 811 ) , DMSO ( 497 , 520 , 557 ) , DNP ( 582 ) , dronabinol ( 527 , 620 ) , duvelisib ( 46 ) , E-cadherin-Fc ( 59 ) , edelfosine ( 598 ) , EF24 ( 541 ) , eflornithine ( 479 ) , EGCG ( 270 , 795 ) , EGF ( 9 , 17 , 53 , 113 , 170 , 244 , 247 , 271 , 286 , 293 , 306 , 307 , 332 , 333 , 341 , 350 , 359 , 368 , 369 , 380 , 390 , 400 , 416 , 435 , 456 , 466 , 485 , 486 , 490 , 513 , 527 , 535 , 567 , 605 , 615 , 622 , 623 , 626 , 630 , 631 , 647 , 648 , 652 , 658 , 660 , 689 , 727 , 731 , 742 , 754 , 776 , 779 , 807 , 818 , 835 , 839 , 841 , 843 , 848 , 861 , 874 , 891 , 894 , 901 ) , EGTA ( 197 , 598 , 841 ) , endostatin ( 858 ) , endothelin ( 843 ) , englerin_A ( 178 ) , enzalutamide ( 254 ) , enzastaurin ( 511 ) , ephrin_A1 ( 295 , 441 ) , ephrin_A4 ( 295 ) , eplerenone ( 628 ) , Epo ( 191 , 470 , 510 , 576 , 806 , 911 ) , equol ( 616 ) , erlotinib ( 187 , 350 , 436 , 695 ) , estradiol ( 372 , 381 , 391 , 405 , 416 , 440 , 577 , 588 , 600 , 603 , 611 , 676 , 745 , 867 , 904 ) , estrogen_deprivation ( 688 , 800 ) , ethanol ( 20 , 805 ) , etoposide ( 675 , 811 ) , ETS ( 35 ) , exercise ( 610 , 650 , 690 ) , exercise training ( 288 ) , factor_XII ( 360 ) , faslodex ( 451 , 683 , 867 ) , fasting ( 147 ) , fedratinib ( 510 ) , fetal growth restriction ( 140 ) , FGF1 ( 177 , 333 , 471 , 613 ) , FGF2 ( 626 , 641 , 666 , 830 ) , FGF9 ( 167 ) , fibronectin ( 163 , 642 , 656 , 857 , 888 , 914 ) , Filipin ( 382 ) , fingolimod ( 43 , 809 ) , fipronil ( 259 ) , FK506 ( 678 , 825 ) , FL ( 43 ) , flagellin ( 544 ) , fluid_shear_stress ( 82 , 340 , 732 , 864 , 889 ) , fluvastatin ( 399 ) , FMK-MEA ( 142 ) , fMLP ( 558 , 791 , 878 , 897 ) , fructose ( 123 ) , fumonisin_B1 ( 807 , 811 ) , gallamine triethiodide ( 881 ) , ganglioside ( 868 ) , Gas6 ( 517 , 865 ) , gastrin ( 419 , 612 ) , GDNF ( 335 , 839 ) , gefitinib ( 195 , 606 , 630 , 631 , 651 , 684 , 699 , 785 ) , geldanamycin ( 502 , 624 , 686 , 785 , 869 , 875 ) , genistein ( 665 , 771 , 794 , 912 ) , GF109203X ( 435 , 444 , 729 , 774 , 823 , 881 ) , GGTI-2418 ( 448 ) , GH ( 147 ) , ghrelin ( 226 , 475 , 573 ) , ginsenoside-Rg1 ( 601 ) , glabridin ( 212 ) , glucagon ( 135 ) , glucose ( 161 , 494 , 734 , 831 ) , glucose_oxidase ( 431 ) , glucose_starvation ( 328 ) , glycyrrhizinic_acid ( 28 ) , GM-CSF ( 102 , 913 ) , Go_6976 ( 582 , 906 ) , GSK2334470 ( 16 , 83 ) , GSK690693 ( 114 ) , GTX-155 ( 532 ) , GTX-221 ( 532 ) , H-89 ( 135 , 340 , 478 , 506 , 558 , 698 ) , H2O2 ( 339 , 489 , 506 , 583 , 589 , 649 , 817 , 895 ) , HA-1077 ( 741 ) , HB-EGF ( 306 ) , HDL ( 812 ) , heart failure ( 472 ) , heat_shock ( 767 , 783 , 862 ) , herbimycin_A ( 665 , 729 , 792 ) , heregulin ( 200 , 307 , 386 , 416 , 418 , 555 , 577 , 588 , 613 , 630 , 785 ) , HGF ( 96 , 113 , 137 , 163 , 244 , 248 , 379 , 626 , 699 , 772 , 857 , 898 ) , high_glucose ( 28 , 122 ) , histamine ( 861 ) , HKI-357 ( 684 ) , HNMPA(AM)3 ( 433 ) , honokiol DCA ( 61 ) , HU-210 ( 821 ) , hypoxia ( 427 , 443 , 801 , 831 , 895 ) , hypoxia/reoxygenation ( 655 ) , ibuprofen ( 31 ) , IC87114 ( 532 , 558 ) , ICAM-2 ( 866 ) , IFN-beta ( 835 ) , IFN-gamma ( 873 ) , IGF-1 ( 20 , 79 , 113 , 159 , 161 , 166 , 200 , 270 , 311 , 319 , 333 , 362 , 369 , 372 , 374 , 397 , 416 , 436 , 437 , 444 , 466 , 476 , 518 , 532 , 538 , 551 , 561 , 585 , 600 , 626 , 664 , 677 , 695 , 698 , 702 , 713 , 726 , 738 , 742 , 746 , 766 , 776 , 782 , 783 , 825 , 834 , 836 , 844 , 846 , 872 , 874 , 901 , 915 , 924 , 926 ) , IGF-2 ( 82 , 103 , 787 ) , IGF1R_inhibitor_II ( 436 ) , IGFBP-3 ( 818 ) , IgG ( 295 ) , IL-13 ( 847 ) , IL-1b ( 349 , 851 ) , IL-24 ( 115 ) , IL-3 ( 521 ) , IL-6 ( 311 , 313 , 526 , 574 , 593 , 670 ) , imatinib ( 58 , 108 , 195 , 295 , 487 , 761 , 792 ) , imipramine ( 807 ) , INCB3619 ( 630 ) , INCB4298 ( 630 ) , INCB8765 ( 630 ) , INK-128 ( 66 , 85 , 142 ) , insulin ( 45 , 101 , 122 , 123 , 135 , 213 , 225 , 267 , 277 , 278 , 282 , 283 , 288 , 319 , 330 , 390 , 398 , 403 , 418 , 422 , 438 , 439 , 453 , 459 , 493 , 508 , 514 , 526 , 530 , 547 , 549 , 559 , 563 , 564 , 566 , 572 , 574