Ser473
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RPHFPQFsysAsGtA   SwissProt Entrez-Gene
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Site Group ID: 447855

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 664 , 687 , 765 , 769 , 821 , 836 , 861 , 880 ) , electrophoretic mobility shift ( 181 , 850 , 876 ) , flow cytometry ( 8 , 282 , 436 , 547 , 746 ) , immunoassay ( 304 ) , immunoprecipitation ( 5 , 14 , 27 , 31 , 33 , 36 , 42 , 50 , 51 , 52 , 74 , 84 , 91 , 97 , 139 , 168 , 190 , 197 , 206 , 221 , 226 , 241 , 247 , 252 , 266 , 273 , 294 , 436 , 439 , 450 , 453 , 460 , 481 , 488 , 533 , 854 , 905 ) , mass spectrometry ( 5 , 15 , 91 , 119 , 139 , 165 , 196 , 203 , 210 , 211 , 212 , 233 , 290 , 291 , 292 , 293 , 318 , 319 , 322 , 323 , 324 , 325 , 326 , 337 , 338 , 345 , 346 , 347 , 348 , 353 , 354 , 355 , 356 , 357 , 358 , 359 , 371 , 372 , 377 , 378 , 388 , 390 , 393 , 394 , 395 , 396 , 397 , 403 , 407 , 412 , 415 , 434 , 571 ) , mass spectrometry (in vitro) ( 295 ) , microscopy-colocalization with upstream kinase ( 498 , 507 , 828 , 840 , 844 ) , mutation of modification site ( 5 , 10 , 11 , 13 , 14 , 15 , 26 , 50 , 52 , 92 , 139 , 143 , 160 , 170 , 179 , 181 , 266 , 273 , 370 , 428 , 436 , 439 , 454 , 480 , 483 , 504 , 506 , 508 , 528 , 567 , 570 , 578 , 635 , 664 , 685 , 694 , 695 , 708 , 714 , 740 , 749 , 764 , 769 , 814 , 828 , 836 , 844 , 854 , 860 , 892 , 902 , 903 , 909 , 912 , 922 , 923 , 925 ) , peptide sequencing ( 40 , 48 , 109 , 392 , 426 , 926 ) , phospho-antibody ( 2 , 5 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 76 , 78 , 79 , 80 , 81 , 82 , 84 , 86 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 96 , 97 , 98 , 100 , 101 , 102 , 103 , 104 , 105 , 107 , 111 , 114 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 126 , 128 , 132 , 134 , 135 , 136 , 139 , 140 , 141 , 142 , 143 , 144 , 148 , 149 , 150 , 151 , 154 , 156 , 159 , 160 , 162 , 164 , 167 , 168 , 169 , 170 , 172 , 173 , 174 , 175 , 178 , 182 , 183 , 186 , 187 , 188 , 190 , 191 , 192 , 194 , 195 , 197 , 198 , 201 , 206 , 207 , 208 , 209 , 213 , 217 , 220 , 221 , 223 , 226 , 230 , 235 , 236 , 240 , 241 , 242 , 243 , 245 , 246 , 247 , 248 , 249 , 251 , 252 , 254 , 255 , 256 , 259 , 260 , 261 , 262 , 264 , 265 , 266 , 268 , 271 , 273 , 275 , 278 , 279 , 281 , 282 , 283 , 284 , 285 , 287 , 288 , 289 , 294 , 295 , 296 , 297 , 300 , 301 , 304 , 307 , 308 , 309 , 311 , 313 , 314 , 315 , 316 , 320 , 321 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 334 , 336 , 339 , 340 , 341 , 342 , 343 , 344 , 349 , 350 , 351 , 352 , 360 , 362 , 363 , 364 , 366 , 367 , 368 , 369 , 370 , 373 , 374 , 375 , 376 , 379 , 380 , 381 , 382 , 384 , 385 , 387 , 389 , 391 , 399 , 400 , 401 , 402 , 404 , 405 , 406 , 407 , 408 , 409 , 411 , 413 , 414 , 416 , 417 , 418 , 419 , 420 , 421 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 435 , 436 , 437 , 438 , 440 , 442 , 443 , 445 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 453 , 454 , 456 , 457 , 458 , 460 , 462 , 463 , 464 , 465 , 466 , 467 , 469 , 470 , 471 , 472 , 473 , 474 , 476 , 477 , 478 , 479 , 480 , 481 , 482 , 483 , 484 , 486 , 487 , 488 , 489 , 490 , 491 , 492 , 493 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 511 , 512 , 513 , 514 , 515 , 516 , 517 , 518 , 519 , 520 , 521 , 522 , 523 , 524 , 526 , 527 , 528 , 529 , 530 , 532 , 533 , 534 , 535 , 536 , 538 , 539 , 540 , 543 , 544 , 545 , 546 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 555 , 556 , 557 , 558 , 559 , 560 , 561 , 562 , 563 , 564 , 565 , 566 , 567 , 568 , 570 , 572 , 573 , 574 , 575 , 576 , 577 , 578 , 579 , 580 , 581 , 582 , 583 , 584 , 585 , 586 , 587 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 605 , 606 , 608 , 610 , 611 , 612 , 613 , 614 , 615 , 616 , 617 , 618 , 619 , 620 , 621 , 622 , 623 , 624 , 625 , 626 , 627 , 628 , 629 , 630 , 631 , 632 , 633 , 634 , 635 , 638 , 640 , 641 , 642 , 643 , 644 , 645 , 646 , 647 , 648 , 649 , 650 , 651 , 652 , 653 , 654 , 655 , 656 , 657 , 658 , 659 , 660 , 661 , 662 , 663 , 664 , 665 , 666 , 667 , 668 , 669 , 670 , 671 , 672 , 673 , 674 , 675 , 676 , 677 , 678 , 679 , 680 , 681 , 682 , 683 , 684 , 685 , 686 , 687 , 688 , 689 , 690 , 691 , 692 , 693 , 694 , 695 , 696 , 697 , 698 , 699 , 700 , 701 , 702 , 703 , 704 , 705 , 706 , 707 , 708 , 709 , 710 , 711 , 712 , 713 , 714 , 716 , 717 , 719 , 720 , 721 , 722 , 723 , 724 , 725 , 726 , 727 , 728 , 729 , 730 , 731 , 732 , 733 , 734 , 735 , 736 , 737 , 738 , 739 , 740 , 741 , 742 , 743 , 744 , 746 , 747 , 748 , 749 , 750 , 751 , 752 , 753 , 754 , 755 , 757 , 758 , 759 , 760 , 761 , 762 , 763 , 764 , 765 , 766 , 767 , 768 , 769 , 770 , 771 , 772 , 773 , 774 , 775 , 776 , 777 , 778 , 779 , 780 , 781 , 782 , 783 , 784 , 785 , 786 , 787 , 788 , 789 , 790 , 791 , 792 , 793 , 796 , 797 , 798 , 799 , 801 , 802 , 803 , 805 , 807 , 809 , 810 , 811 , 812 , 813 , 814 , 815 , 816 , 817 , 818 , 819 , 820 , 821 , 822 , 824 , 825 , 826 , 827 , 828 , 829 , 830 , 832 , 833 , 834 , 835 , 836 , 837 , 838 , 839 , 840 , 841 , 842 , 843 , 844 , 845 , 846 , 848 , 849 , 850 , 851 , 852 , 853 , 854 , 855 , 856 , 857 , 858 , 859 , 860 , 861 , 862 , 863 , 864 , 865 , 866 , 867 , 868 , 869 , 870 , 871 , 872 , 873 , 874 , 875 , 876 , 877 , 878 , 879 , 880 , 881 , 882 , 883 , 884 , 885 , 886 , 887 , 888 , 889 , 891 , 892 , 893 , 894 , 895 , 896 , 897 , 898 , 899 , 900 , 901 , 902 , 903 , 904 , 905 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 916 , 917 , 918 , 919 , 921 , 922 , 927 , 928 , 929 , 930 ) , phosphoamino acid analysis ( 229 , 280 , 383 , 510 , 854 ) , phosphopeptide mapping ( 836 ) , western blotting ( 2 , 5 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 76 , 78 , 79 , 80 , 81 , 82 , 84 , 86 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 96 , 97 , 98 , 100 , 101 , 102 , 103 , 104 , 105 , 107 , 109 , 111 , 114 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 126 , 128 , 132 , 134 , 135 , 136 , 139 , 140 , 141 , 142 , 144 , 148 , 149 , 150 , 151 , 154 , 156 , 159 , 160 , 162 , 164 , 167 , 168 , 169 , 170 , 172 , 173 , 174 , 175 , 178 , 179 , 181 , 182 , 183 , 185 , 186 , 187 , 190 , 191 , 192 , 194 , 195 , 197 , 198 , 201 , 206 , 207 , 208 , 209 , 213 , 217 , 220 , 221 , 223 , 226 , 229 , 230 , 235 , 236 , 240 , 241 , 242 , 243 , 245 , 246 , 247 , 248 , 249 , 251 , 252 , 254 , 255 , 256 , 259 , 260 , 261 , 262 , 265 , 266 , 268 , 271 , 273 , 275 , 278 , 279 , 280 , 281 , 283 , 285 , 287 , 288 , 289 , 294 , 295 , 296 , 297 , 300 , 301 , 307 , 308 , 309 , 311 , 313 , 314 , 316 , 320 , 321 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 334 , 336 , 340 , 341 , 342 , 343 , 344 , 349 , 350 , 351 , 352 , 360 , 362 , 363 , 364 , 366 , 367 , 368 , 369 , 370 , 373 , 374 , 375 , 376 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , 387 , 389 , 391 , 392 , 399 , 400 , 401 , 402 , 404 , 405 , 406 , 407 , 408 , 411 , 413 , 416 , 417 , 418 , 419 , 420 , 421 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 435 , 436 , 437 , 438 , 439 , 440 , 442 , 443 , 445 , 446 , 447 , 449 , 450 , 451 , 452 , 453 , 454 , 456 , 458 , 460 , 462 , 463 , 464 , 465 , 466 , 467 , 469 , 470 , 471 , 472 , 473 , 474 , 477 , 478 , 479 , 480 , 481 , 482 , 483 , 484 , 486 , 487 , 488 , 489 , 490 , 491 , 492 , 493 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 517 , 518 , 519 , 520 , 521 , 522 , 523 , 524 , 526 , 527 , 528 , 529 , 530 , 532 , 533 , 534 , 535 , 536 , 538 , 539 , 540 , 543 , 544 , 545 , 546 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 555 , 556 , 557 , 559 , 560 , 561 , 562 , 563 , 564 , 566 , 567 , 568 , 570 , 572 , 573 , 574 , 575 , 576 , 577 , 578 , 579 , 580 , 581 , 582 , 583 , 584 , 585 , 586 , 587 , 588 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 605 , 606 , 608 , 610 , 611 , 612 , 613 , 614 , 615 , 616 , 617 , 618 , 620 , 621 , 622 , 623 , 624 , 625 , 626 , 627 , 629 , 630 , 631 , 632 , 633 , 634 , 635 , 638 , 640 , 641 , 642 , 643 , 644 , 646 , 647 , 648 , 649 , 650 , 651 , 654 , 655 , 656 , 657 , 658 , 659 , 660 , 662 , 665 , 667 , 668 , 670 , 678 , 679 , 683 , 685 , 686 , 689 , 690 , 691 , 694 , 696 , 698 , 700 , 702 , 703 , 704 , 705 , 706 , 707 , 708 , 709 , 712 , 713 , 716 , 717 , 719 , 720 , 724 , 725 , 726 , 728 , 729 , 731 , 732 , 733 , 734 , 735 , 737 , 738 , 740 , 742 , 748 , 749 , 750 , 757 , 758 , 759 , 760 , 763 , 765 , 766 , 767 , 768 , 769 , 771 , 773 , 774 , 777 , 778 , 779 , 780 , 782 , 783 , 784 , 787 , 788 , 789 , 790 , 791 , 792 , 796 , 797 , 798 , 802 , 803 , 805 , 807 , 809 , 811 , 813 , 814 , 816 , 818 , 819 , 820 , 822 , 825 , 827 , 828 , 829 , 830 , 832 , 833 , 834 , 836 , 837 , 838 , 839 , 841 , 842 , 844 , 845 , 846 , 848 , 849 , 851 , 853 , 854 , 855 , 859 , 860 , 862 , 863 , 864 , 866 , 867 , 869 , 871 , 874 , 877 , 886 , 887 , 889 , 892 , 898 , 899 , 902 , 903 , 904 , 905 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 916 , 917 , 918 , 922 , 926 , 927 , 928 , 929 , 930 )
Disease tissue studied:
ataxia-telangiectasia ( 321 ) , adrenal cancer ( 168 , 758 , 828 , 841 ) , pheochromocytoma ( 168 , 758 , 828 , 841 ) , bladder cancer ( 279 , 502 , 626 ) , bone cancer ( 83 , 159 , 178 , 368 , 413 , 449 , 462 , 520 , 586 , 698 ) , Ewing's sarcoma ( 520 ) , osteosarcoma ( 368 ) , brain cancer ( 33 , 42 , 49 , 107 , 191 , 259 , 275 , 301 , 314 , 349 , 366 , 369 , 380 , 413 , 416 , 443 , 454 , 587 , 588 , 604 , 611 , 649 , 650 , 665 , 687 , 735 , 749 , 761 , 861 , 898 , 910 , 930 ) , astrocytoma ( 687 , 861 ) , glioblastoma ( 33 , 42 , 49 , 107 , 259 , 275 , 301 , 314 , 349 , 366 , 413 , 454 , 587 , 588 , 604 , 611 , 649 , 650 , 665 , 735 , 749 , 761 , 898 , 910 ) , glioblastoma multiforme ( 139 , 191 , 259 , 314 , 380 , 443 , 611 , 649 , 761 ) , glioma ( 33 , 42 , 49 , 107 , 139 , 191 , 259 , 275 , 301 , 314 , 349 , 366 , 380 , 413 , 443 , 454 , 587 , 588 , 604 , 611 , 649 , 650 , 665 , 735 , 749 , 761 , 898 , 910 ) , medulloblastoma ( 416 ) , Schwannoma ( 369 , 930 ) , breast cancer ( 10 , 11 , 27 , 35 , 38 , 40 , 52 , 80 , 90 , 94 , 139 , 142 , 144 , 150 , 160 , 169 , 173 , 174 , 187 , 209 , 217 , 221 , 230 , 248 , 252 , 254 , 256 , 271 , 273 , 281 , 288 , 296 , 300 , 308 , 334 , 336 , 343 , 363 , 366 , 370 , 373 , 375 , 382 , 387 , 392 , 406 , 411 , 413 , 417 , 419 , 429 , 433 , 442 , 447 , 450 , 452 , 453 , 456 , 462 , 471 , 478 , 488 , 492 , 499 , 504 , 506 , 507 , 508 , 514 , 533 , 552 , 557 , 573 , 582 , 602 , 605 , 613 , 615 , 624 , 626 , 633 , 640 , 645 , 656 , 659 , 679 , 690 , 696 , 704 , 712 , 733 , 744 , 747 , 771 , 778 , 787 , 802 , 820 , 840 , 845 , 846 , 851 , 869 , 903 ) , breast adenocarcinoma ( 38 , 173 , 174 , 187 , 221 , 462 , 840 ) , breast cancer, triple negative ( 142 , 173 , 174 , 187 , 221 , 462 ) , cervical cancer ( 381 , 508 , 724 , 842 ) , cervical adenocarcinoma ( 508 , 842 ) , colorectal cancer ( 5 , 48 , 55 , 67 , 78 , 143 , 164 , 249 , 296 , 329 , 408 , 469 , 471 , 486 , 490 , 502 , 511 , 559 , 570 , 629 , 659 , 725 , 838 , 849 , 864 ) , colorectal carcinoma ( 5 , 48 , 55 , 67 , 78 , 143 , 164 , 249 , 296 , 329 , 408 , 469 , 471 , 486 , 490 , 502 , 511 , 559 , 570 , 629 , 659 , 725 , 838 , 849 , 864 ) , endometrial cancer ( 9 , 430 ) , endometrial adenocarcinoma ( 9 , 430 ) , gastric cancer ( 140 , 149 , 318 , 319 , 322 , 345 , 347 , 348 , 355 , 356 , 388 , 393 , 394 , 395 , 407 , 420 , 434 , 460 , 513 , 527 , 763 ) , gastric carcinoma ( 140 , 149 , 318 , 319 , 322 , 345 , 347 , 348 , 355 , 356 , 388 , 393 , 394 , 395 , 407 , 420 , 434 , 460 , 513 , 527 ) , GIST ( 763 ) , HNSCC ( 194 ) , kidney cancer ( 7 , 175 , 179 , 429 , 470 , 660 ) , papillary kidney cancer ( 88 ) , leukemia ( 2 , 44 , 47 , 59 , 63 , 103 , 105 , 192 , 236 , 379 , 390 , 418 , 477 , 489 , 512 , 535 , 545 , 645 , 694 , 712 , 766 , 830 , 913 , 915 ) , acute lymphocytic leukemia ( 545 ) , acute myelogenous leukemia ( 44 , 47 , 192 , 379 , 477 , 512 , 535 , 645 , 712 , 913 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 103 , 489 , 645 , 915 ) , chronic lymphocytic leukemia ( 830 ) , chronic myelogenous leukemia ( 19 , 59 , 63 , 390 , 418 , 694 ) , T cell leukemia ( 2 , 236 ) , liver cancer ( 34 , 36 , 77 , 84 , 97 , 118 , 136 , 141 , 243 , 268 , 284 , 400 , 401 , 424 , 516 , 528 , 585 , 595 , 605 , 610 , 641 , 703 , 706 , 716 , 803 ) , hepatocellular carcinoma ( 45 , 77 , 97 , 136 ) , squamous cell carcinoma of the liver ( 243 , 401 ) , lung cancer ( 16 , 18 , 25 , 53 , 55 , 67 , 76 , 82 , 86 , 100 , 114 , 116 , 117 , 134 , 188 , 195 , 213 , 242 , 245 , 271 , 288 , 323 , 324 , 325 , 326 , 329 , 342 , 346 , 351 , 353 , 354 , 357 , 358 , 359 , 363 , 377 , 378 , 396 , 407 , 413 , 438 , 448 , 452 , 456 , 457 , 469 , 487 , 490 , 497 , 529 , 540 , 585 , 608 , 632 , 633 , 638 , 658 , 674 , 686 , 760 , 773 , 888 ) , non-small cell lung cancer ( 16 , 18 , 25 , 30 , 53 , 55 , 67 , 76 , 82 , 86 , 100 , 114 , 116 , 117 , 134 , 188 , 195 , 323 , 324 , 325 , 326 , 342 , 346 , 351 , 353 , 354 , 357 , 358 , 359 , 377 , 378 , 396 , 407 , 438 , 448 , 452 , 490 , 529 , 540 , 632 , 633 , 638 , 658 , 686 , 888 ) , non-small cell lung adenocarcinoma ( 16 , 18 , 25 , 53 , 55 , 76 , 82 , 86 , 114 , 116 , 117 , 134 , 188 , 325 , 326 , 346 , 353 , 354 , 357 , 358 , 359 , 396 , 407 ) , non-small cell large cell lung carcinoma ( 16 , 25 , 116 , 188 ) , non-small cell squamous cell lung carcinoma ( 325 , 326 , 346 , 396 , 407 , 490 ) , lymphoma ( 26 , 132 , 282 , 374 , 384 , 385 , 467 , 530 , 545 , 594 , 622 , 645 , 727 , 811 , 818 ) , anaplastic large cell lymphoma ( 282 , 374 , 545 ) , B cell lymphoma ( 13 , 26 , 594 , 818 ) , Burkitt's lymphoma ( 594 ) , Hodgkin's lymphoma ( 385 , 727 ) , non-Hodgkin's lymphoma ( 26 ) , mantle cell lymphoma ( 26 ) , PEL ( 132 ) , T cell lymphoma ( 282 , 374 , 384 , 622 ) , neuroblastoma ( 81 , 119 , 247 , 260 , 278 , 481 , 515 , 539 , 587 , 606 , 643 , 757 , 758 , 827 , 829 , 874 , 928 ) , ovarian cancer ( 31 , 54 , 68 , 120 , 121 , 150 , 241 , 296 , 339 , 362 , 369 , 389 , 476 , 543 , 562 , 590 , 593 , 667 , 756 , 778 , 845 , 867 ) , ovarian epithelial carcinoma ( 543 ) , pancreatic cancer ( 12 , 20 , 30 , 55 , 56 , 70 , 72 , 75 , 190 , 264 , 366 , 469 , 524 , 614 , 689 , 713 , 737 ) , pancreatic carcinoma ( 12 , 20 , 56 , 70 , 72 , 75 , 190 , 366 , 469 , 524 , 614 , 689 , 713 , 737 ) , pancreatic islet cell cancer ( 30 ) , multiple myeloma ( 17 , 64 ) , prostate cancer ( 15 , 42 , 84 , 91 , 98 , 197 , 198 , 206 , 235 , 243 , 255 , 271 , 296 , 309 , 333 , 344 , 415 , 426 , 452 , 462 , 463 , 464 , 465 , 471 , 505 , 514 , 538 , 617 , 625 , 631 , 644 , 655 , 717 , 749 , 752 , 767 , 791 , 864 , 912 , 916 , 929 ) , melanoma skin cancer ( 62 , 208 , 352 , 427 , 436 , 506 , 623 , 629 , 651 , 740 , 822 ) , small intestine cancer ( 763 ) , fibrosarcoma of soft tissue ( 104 , 287 , 329 , 500 , 502 , 837 , 864 ) , leiomyosarcoma ( 287 ) , rhabdomyosarcoma ( 41 , 156 , 520 , 544 , 789 ) , cancer, squamous cell carcinoma ( 194 , 243 , 313 , 381 ) , thyroid cancer ( 616 , 708 ) , anaplastic thyroid carcinoma ( 708 ) , follicular thyroid carcinoma ( 616 , 708 ) , papillary thyroid carcinoma ( 708 ) , diabetes mellitus ( 532 ) , type 2 diabetes ( 289 , 532 ) , hepatitis ( 509 ) , neurofibromatosis type 1 ( 405 ) , Parkinson's disease ( 425 )
Relevant cell line - cell type - tissue:
'brain, caudate-putamen' ( 539 ) , 'brain, cerebellum' ( 416 ) , 'brain, midbrain' ( 425 ) , 'hematopoietic progenitor, CD34+'-blood ( 280 ) , 'macrophage, alveolar'-lung ( 895 ) , 'muscle, skeletal' ( 148 , 283 , 289 , 495 , 501 , 532 , 544 , 549 , 612 , 648 , 652 , 669 , 672 , 683 , 692 , 693 , 702 , 703 , 729 ) , 'muscle, skeletal' [SGK1 (human), homozygous knockout] ( 728 ) , 'muscle, smooth' ( 729 ) , 'neuron, cortical'-brain ( 663 ) , 'neuron, dorsal root ganglion'-brain ( 748 ) , 'neuron, hippocampal'-brain ( 663 ) , 'stem, embryonic' ( 201 , 367 ) , 'stem, mesenchymal' ( 21 ) , 'stem, prostate cancer' ( 32 ) , 1-LN (prostate cell) ( 197 ) , 1321N1 (glial) ( 883 ) , 201T ('epithelial, lung') ( 245 ) , 21T (breast cell) ( 366 ) , 22Rv1 (prostate cell) ( 505 ) , 293 (epithelial) ( 74 , 89 , 103 , 154 , 185 , 190 , 191 , 251 , 266 , 320 , 331 , 333 , 376 , 391 , 404 , 409 , 413 , 429 , 436 , 437 , 440 , 443 , 454 , 456 , 458 , 472 , 473 , 491 , 510 , 519 , 526 , 539 , 546 , 553 , 578 , 581 , 584 , 599 , 620 , 633 , 641 , 647 , 661 , 664 , 666 , 676 , 688 , 699 , 704 , 720 , 737 , 744 , 767 , 783 , 785 , 805 , 844 , 853 , 856 , 873 , 881 , 893 , 899 , 901 , 917 , 922 , 926 ) , 293 (epithelial) [ADRB2 (human), transfection] ( 493 ) , 293 (epithelial) [MDM2 (human)] ( 749 ) , 293 (epithelial) [Raptor (human), transfection] ( 294 ) , 293E (epithelial) ( 570 , 675 ) , 293T (epithelial) ( 52 , 63 , 94 , 96 , 186 , 220 , 295 , 297 , 366 , 431 , 439 , 472 , 480 , 564 , 568 , 570 , 573 , 579 , 677 , 695 , 696 , 711 , 775 , 864 , 865 , 882 ) , 2C4 (fibroblast) ( 875 ) , 2fTGH (fibroblast) ( 875 ) , 32D (myeloid) ( 633 ) , 3T3 (fibroblast) ( 84 , 178 , 191 , 436 , 483 , 523 , 540 , 659 , 664 , 842 , 923 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 769 , 770 , 783 , 817 , 839 , 868 , 878 ) , 3T3 (fibroblast) [Src (human)] ( 608 ) , 3T3-L1 (fibroblast) ( 172 , 549 , 574 , 716 ) , 41M (ovarian) ( 590 ) , 769P (renal) ( 7 , 813 ) , 786-O (renal) ( 7 , 179 ) , A172 (glial) ( 107 , 588 , 680 ) , A2780 (ovarian) ( 543 , 753 ) , A293T ('renal, embryonic') ( 564 ) , A375 (melanocyte) ( 62 , 208 , 427 , 623 , 629 ) , A427 (pulmonary) ( 16 ) , A431 (epithelial) ( 55 , 351 , 551 , 701 , 720 ) , A498 (renal) ( 813 ) , A549 (pulmonary) ( 16 , 18 , 25 , 53 , 55 , 76 , 82 , 86 , 116 , 117 , 188 , 195 , 213 , 245 , 271 , 329 , 342 , 363 , 407 , 413 , 438 , 456 , 457 , 469 , 487 , 490 , 529 , 540 , 585 , 632 , 638 , 674 , 701 , 711 , 760 , 773 ) , A549 (pulmonary) [SRXN1 (human), transfection] ( 497 ) , ACE (endothelial) ( 832 ) , ACHN (renal) ( 813 ) , ACN ( 81 ) , adipocyte-adipose tissue ( 46 , 705 ) , adipose tissue ( 73 , 561 ) , AGS (gastric) ( 140 , 460 , 527 ) , AGS (gastric) [CCKBR (human), transfection] ( 420 ) , AML10 (myeloid) ( 47 ) , AML11 (myeloid) ( 47 ) , AR42J (pancreatic) ( 614 ) , artery-heart ( 634 ) , Aspc1 (pancreatic) ( 12 , 70 , 75 , 737 ) , astrocyte ( 124 ) , astrocyte [p16-INK4A (human), homozygous knockout] ( 191 ) , astrocyte-'brain, striatum' ( 807 ) , AT52RM (lymphoblastoid) ( 321 ) , AU565 (breast cell) ( 187 , 582 ) , B lymphocyte ( 594 , 830 ) , B lymphocyte-spleen ( 584 ) , BAEC (endothelial) ( 491 , 567 , 575 , 577 , 620 , 685 , 734 , 782 , 788 , 798 , 819 , 866 , 889 , 894 ) , BaF3 ('B lymphocyte, precursor') ( 44 , 63 , 316 ) , BaF3 ('B lymphocyte, precursor') [EGFR (human)] ( 608 ) , BC3 (B lymphocyte) ( 132 ) , BE (melanocyte) ( 740 ) , BEAS-2B (epithelial) ( 58 , 633 ) , BEL7402 (hepatic) ( 36 ) , Ben-Men-1 ( 930 ) , BeWo ( 445 ) , BeWo31 ( 445 ) , BG-1 ( 373 ) , BHK (fibroblast) [HRas (human)] ( 558 ) , BHK (fibroblast) [KRas (human)] ( 558 ) , BHK (fibroblast) [Sin1 (human)] ( 558 ) , BJ (fibroblast) ( 598 ) , blood ( 141 ) , Bon1 (pancreatic) ( 30 ) , bone marrow ( 168 , 765 ) , BPH-1 (epithelial) ( 333 ) , brain ( 587 ) , breast ( 419 , 679 ) , breast cell-breast ( 840 ) , BT-474 (breast cell) ( 11 , 40 , 150 , 174 , 288 , 366 , 557 , 582 , 696 , 721 , 851 ) , BT-549 (breast cell) ( 173 , 174 , 370 , 659 ) , BxPC-3 (pancreatic) ( 737 ) , C2C12 (myoblast) ( 41 , 668 , 729 , 789 ) , C2C12 (myoblast) [SPRY2 (human), transfection] ( 668 ) , C33-A (cervical) ( 724 ) , C4-2 (prostate cell) ( 426 ) , Caco-2 (intestinal) ( 629 ) , Caki-1 (renal) ( 470 , 813 ) , Calu-1 (squamous) ( 438 , 540 ) , CAMA-1 (breast cell) ( 38 ) , Caov-3 (ovarian) ( 590 ) , Capan1 (pancreatic) ( 56 , 737 ) , Capan2 (pancreatic) ( 65 ) , CCRF-CEM (T lymphocyte) ( 236 ) , CD18/HPAF (pancreatic) ( 56 ) , CEF ( 14 ) , CEM (T lymphocyte) ( 545 ) , CFPAC-1 (pancreatic) ( 563 ) , CH27 (squamous) ( 868 ) , CHL (fibroblast) ( 887 ) , CHO (fibroblast) ( 37 , 375 , 549 , 664 , 731 ) , CHO (fibroblast) [EphB1 (human), transfection] ( 817 , 922 ) , CHO (fibroblast) [EPOR (human)] ( 578 ) , CHO (fibroblast) [INSR (human), transfection] ( 902 ) , CHO (fibroblast) [MAS1 (human)] ( 592 ) , chondrocyte ( 421 ) , CL1-0 (pulmonary) ( 117 , 195 ) , CL1-5 (pulmonary) ( 53 ) , COLO-357 (pancreatic) ( 366 ) , colon ( 78 ) , COS (fibroblast) ( 483 , 492 , 564 , 567 , 614 , 654 , 685 , 691 , 723 , 748 , 769 , 814 , 828 , 833 , 836 , 841 , 864 , 873 , 884 , 893 , 894 , 896 , 903 , 905 , 918 , 925 ) , CTL-EN (T lymphocyte) ( 777 ) , D425 ( 101 ) , Daoy ( 416 ) , DDT1-MF2 (myoblast) ( 863 ) , DF1 (fibroblast) ( 586 ) , DLBCL (B lymphocyte) ( 13 ) , DLD1 (intestinal) ( 5 , 249 , 408 , 502 , 659 , 681 ) , DM4 (melanocyte) ( 427 ) , DT40 (B lymphocyte) ( 594 ) , DU 145 (prostate cell) ( 197 , 452 , 464 , 471 , 551 , 791 , 858 , 879 , 916 ) , EA.hy 926 (endothelial) ( 126 , 872 , 906 ) , embryo ( 586 ) , endothelial-aorta ( 738 , 814 , 825 , 891 , 900 ) , endothelial-pulmonary artery ( 779 ) , endothelial-vein ( 743 , 834 , 892 ) , eosinophil ( 793 ) , epithelial ( 498 ) , epithelial-'kidney, tubule, proximal' ( 591 ) , epithelial-lens ( 327 ) , epithelial-prostate ( 644 ) , erythroblast ( 913 ) , ES (stem) ( 898 ) , ES2 (ovarian) ( 241 , 339 ) , ESC ( 451 ) , FaDu (squamous) ( 194 ) , Fao (hepatic) ( 549 ) , fibroblast ( 489 ) , fibroblast-embryo ( 181 , 185 , 428 ) , fibroblast-foreskin ( 139 , 773 ) , fibroblast-skin ( 726 ) , FL5.12 (lymphoid) ( 523 ) , Flow2000 ( 92 ) , GBM39 (astrocyte) ( 191 ) , GI-101A (breast cell) ( 778 , 845 ) , GIST544 (gastric) ( 763 ) , GIST882 (gastric) ( 763 ) , glial ( 42 ) , GM0637 (fibroblast) ( 714 ) , GM07078 (lymphoblastoid) ( 321 ) , GM08391 (fibroblast) ( 714 ) , GM09607 (fibroblast) ( 714 ) , GP293 (fibroblast) ( 63 ) , GRANTA-519 (B lymphocyte) ( 26 ) , GTL-16 (gastric) ( 407 ) , H19-7 (neuron) [IGF1R (human)] ( 680 ) , HaCaT (keratinocyte) ( 39 , 383 , 768 , 810 , 885 ) , HAEC (endothelial) ( 517 , 575 , 592 , 618 , 627 , 646 , 801 ) , HAK-1A (hepatic) ( 45 ) , HAK-1B (hepatic) ( 45 ) , HBEC3 (epithelial) ( 351 , 564 ) , HBL-100 (breast cell) ( 174 ) , HCC1806 (breast cell) ( 142 ) , HCC1937 (breast cell) ( 533 ) , HCC827 (pulmonary) ( 116 ) , HCCLM3 (hepatic) ( 77 ) , HCN-2 ('neuron, cortical') ( 435 ) , HCT116 (intestinal) ( 5 , 48 , 55 , 67 , 78 , 164 , 329 , 408 , 469 , 471 , 490 , 502 , 511 , 681 , 838 ) , HCT15 (intestinal) ( 143 ) , HDMEC (endothelial) ( 285 ) , heart ( 474 ) , HEI-193 (Schwann) ( 369 , 930 ) , HEL (erythroid) ( 489 ) , HeLa (cervical) ( 24 , 51 , 55 , 84 , 135 , 139 , 144 , 207 , 226 , 246 , 261 , 265 , 329 , 331 , 360 , 363 , 370 , 397 , 399 , 452 , 471 , 549 , 551 , 563 , 570 , 578 , 610 , 677 , 711 , 720 , 728 , 750 , 772 , 784 , 809 , 815 , 850 , 855 , 875 ) , HeLa S3 (cervical) ( 508 , 842 ) , hematopoietic progenitor-bone marrow ( 589 ) , hepatocyte ( 185 , 424 ) , hepatocyte-liver ( 10 , 693 , 774 ) , HepG2 (hepatic) ( 34 , 36 , 84 , 141 , 268 , 284 , 400 , 424 , 516 , 528 , 574 , 585 , 595 , 605 , 610 , 672 , 703 , 706 , 736 , 803 , 857 ) , HEY (ovarian) ( 120 , 339 , 778 , 845 ) , HFF1 (fibroblast) ( 28 ) , HGS-396 ( 287 ) , HGS-446 ( 287 ) , HL-7702 (hepatic) ( 170 ) , HL60 (myeloid) ( 105 , 799 , 821 , 880 ) , HMEC (endothelial) ( 93 , 366 , 488 , 764 ) , HMVEC (endothelial) ( 671 , 835 ) , HN5 (squamous) ( 381 , 697 ) , HPAC (pancreatic) ( 72 ) , HPB-ALL (T lymphocyte) ( 811 ) , HPCA (prostate cell) ( 741 ) , HS294T (melanocyte) ( 427 ) , HSC (squamous) ( 243 , 401 ) , HSC-3 (squamous) ( 243 ) , HSC-4 (squamous) ( 243 ) , HT-29 (intestinal) ( 296 , 486 , 511 , 570 , 695 , 711 , 725 , 849 ) , HT1080 (fibroblast) ( 104 , 287 , 329 , 500 , 502 , 864 , 897 ) , HUES-1 ('stem, embryonic') ( 23 ) , HUES-7 ('stem, embryonic') ( 23 ) , HUES-9 ('stem, embryonic') ( 23 ) , Huh7 (hepatic) ( 136 , 516 , 641 ) , HUT-78 (T lymphocyte) ( 384 , 622 ) , HUVEC (endothelial) ( 79 , 122 , 123 , 340 , 402 , 466 , 473 , 479 , 482 , 502 , 508 , 576 , 596 , 603 , 618 , 630 , 662 , 671 , 685 , 731 , 762 , 773 , 780 , 781 , 790 , 824 , 860 , 871 , 877 , 878 , 880 , 884 , 906 , 907 , 909 , 927 ) , HUVEC (endothelial) [IRS1 (human)] ( 780 ) , IGROV1 (ovarian) ( 389 , 812 ) , IMR-90 (fibroblast) ( 5 , 195 , 598 ) , IMR32 (neural crest) ( 587 ) , IOSE-29 (ovarian) ( 812 ) , IOSE-398 (ovarian) ( 241 ) , IR938F (B lymphocyte) ( 818 ) , Ishikawa (endometrial) ( 430 ) , JAR (placental) ( 307 ) , JB (epithelial) ( 684 ) , JEKO-1 (B lymphocyte) ( 26 ) , Jurkat (T lymphocyte) ( 2 , 165 , 203 , 290 , 291 , 292 , 293 , 330 , 337 , 338 , 371 , 372 , 384 , 403 , 412 , 545 , 571 , 580 , 622 , 682 , 732 , 739 , 746 , 811 , 818 , 854 , 868 , 911 ) , K562 (erythroid) ( 59 , 63 , 390 , 418 , 694 ) , Karpas-299 (T lymphocyte) ( 282 , 374 ) , Kasumi-1 (myeloid) ( 379 ) , KATO III (gastric) ( 407 , 434 ) , KCL22 (myeloid) ( 59 ) , KELLY (neural crest) ( 587 ) , keratinocyte ( 10 , 850 ) , keratinocyte-skin ( 797 ) , KG-1 (myeloid) ( 645 ) , kidney ( 429 , 470 ) , KLE (endometrial) ( 9 ) , KM-H2 (lymphoid) ( 727 ) , KPL-4 (breast cell) ( 187 ) , Ku-19-20 (renal) ( 813 ) , Kyse450 (squamous) ( 653 ) , L02 (hepatic) ( 118 , 229 ) , L1236 (lymphoid) ( 727 ) , L3.6p1 (pancreatic) ( 56 ) , L540 (lymphoid) ( 385 ) , L6 (myoblast) ( 549 , 669 , 848 , 926 ) , LAN-1 (neural crest) ( 481 ) , LCL (lymphoblastoid) ( 304 , 321 ) , Leio-177 ( 287 ) , liver ( 509 , 585 , 703 , 716 ) , LLC-PK1 (epithelial) ( 566 , 921 ) , LN-Z308 (glial) ( 604 ) , LN229 (glial) ( 42 , 49 , 259 , 349 , 649 ) , LNCaP (prostate cell) ( 91 , 98 , 198 , 255 , 271 , 309 , 344 , 415 , 462 , 471 , 505 , 538 , 617 , 625 , 631 , 749 , 759 , 767 , 813 , 912 , 916 , 929 ) , lung ( 61 , 377 , 378 , 414 , 448 , 632 ) , lymphocyte-blood ( 8 , 19 , 854 ) , M059J (glial) ( 454 , 550 ) , M14-MEL (melanocyte) ( 651 ) , macrophage-blood ( 723 ) , macrophage-bone marrow ( 43 ) , mammary gland ( 659 ) , mast-bone marrow ( 584 ) , MCF-10A (breast cell) ( 90 , 94 , 169 , 248 , 296 , 370 , 471 , 499 , 633 , 659 , 675 , 771 , 820 , 845 ) , MCF-10A (breast cell) [GAB2 (human), transfection] ( 492 ) , MCF-7 (breast cell) ( 11 , 27 , 139 , 150 , 160 , 174 , 187 , 209 , 252 , 254 , 256 , 273 , 281 , 336 , 343 , 373 , 375 , 406 , 411 , 413 , 417 , 419 , 429 , 433 , 442 , 452 , 453 , 462 , 478 , 488 , 506 , 514 , 551 , 552 , 563 , 573 , 602 , 605 , 613 , 615 , 626 , 640 , 645 , 656 , 675 , 701 , 704 , 712 , 733 , 744 , 747 , 775 , 802 , 846 , 869 , 903 ) , MCF-7 (breast cell) [Akt1 (human)] ( 640 ) , MCF-7 (breast cell) [CYP19A1 (human)] ( 690 ) , MCF-7 (breast cell) [EGFR (human)] ( 640 ) , MCF-7 (breast cell) [MEK1 (human)] ( 640 ) , MCF-7 (breast cell) [Src (human)] ( 624 ) , MCF10A1 (epithelial) ( 50 , 173 , 256 ) , MDA-IBC-3 (breast cell) ( 187 ) , MDA-MB-231 (breast cell) ( 10 , 11 , 40 , 52 , 80 , 144 , 173 , 174 , 187 , 221 , 230 , 248 , 271 , 296 , 300 , 373 , 447 , 450 , 456 , 478 , 504 , 514 , 533 , 659 , 679 , 733 , 869 ) , MDA-MB-361 (breast cell) ( 174 , 368 , 851 ) , MDA-MB-435 (breast cell) ( 174 , 217 , 363 , 563 , 659 , 869 ) , MDA-MB-453 (breast cell) ( 174 , 471 , 563 , 851 ) , MDA-MB-468 (breast cell) ( 173 , 174 , 187 , 221 , 392 , 450 , 456 , 462 , 471 , 508 , 533 , 582 , 659 , 755 ) , MDAH2774 (ovarian) ( 563 ) , MDCK (epithelial) ( 855 , 859 ) , ME-180 (cervical) ( 381 ) , MEF (fibroblast) ( 74 , 84 , 139 , 162 , 265 , 404 , 439 , 454 , 539 , 540 , 550 , 570 , 659 ) , MEF (fibroblast) [BRCA1 (mouse), transgenic] ( 254 ) , MEF (fibroblast) [Etk (human), heterozygous knockout] ( 183 ) , MEF (fibroblast) [IGF1R (mouse)] ( 778 ) , MEF (fibroblast) [Myc (mouse)] ( 651 ) , MEF (fibroblast) [p70S6K (mouse), homozygous knockout] ( 367 ) , MEF (fibroblast) [RICTOR (human), homozygous knockout] ( 331 ) , MEF (fibroblast) [TSC22D2 (human)] ( 551 ) , MEL624 (melanocyte) ( 427 ) , melanocyte-skin [IKKB (mouse), homozygous knockout] ( 352 ) , mesangial ( 621 , 719 ) , mesenchymal ( 61 ) , MeWo (melanocyte) ( 427 , 623 ) , MFH-841 ( 287 ) , MFH-M ( 287 ) , MG63 (bone cell) ( 368 ) , MHCC97-L (hepatic) ( 77 ) , MIA PaCa (pancreatic) ( 551 ) , MIA PaCa-2 (pancreatic) ( 72 , 469 , 737 ) , microvessel endothelial ( 350 ) , MIN6 (pancreatic) ( 524 ) , MKN-45 (gastric) ( 196 , 318 , 319 , 322 , 345 , 347 , 348 , 355 , 356 , 388 , 393 , 394 , 395 , 527 ) , MKN-74 (gastric) ( 460 ) , ML-1 (myeloid) ( 616 ) , Mo7e (myeloid) ( 766 ) , MOLT-4 (T lymphocyte) ( 622 ) , mononuclear ( 432 , 601 ) , MPNST724 ( 287 ) , MRC5 (fibroblast) ( 82 , 502 ) , MSN (neuron) ( 754 ) , MTSV (epithelial) ( 709 ) , muscle ( 673 ) , Mv1Lu (epithelial) ( 670 ) , MV4-11 (macrophage) ( 44 , 47 ) , myeloid ( 751 ) , myeloid-bone marrow ( 518 ) , myoblast ( 565 ) , myocyte-heart ( 642 , 657 , 792 , 886 ) , NA (squamous) ( 243 ) , Namalwa (B lymphocyte) ( 594 ) , NB-4 (myeloid) ( 645 , 712 ) , NBS-ILB1 (fibroblast) ( 321 ) , NCI-H1299 (pulmonary) ( 67 , 116 , 195 , 438 , 490 , 638 ) , NCI-H157 (pulmonary) ( 67 , 438 , 452 , 540 , 695 ) , NCI-H1650 (pulmonary) ( 342 , 490 , 686 ) , NCI-H1666 (pulmonary) ( 632 ) , NCI-H1703 (squamous) ( 196 , 325 , 326 , 346 , 396 , 407 , 490 ) , NCI-H1781 (pulmonary) ( 633 ) , NCI-H1792 (pulmonary) ( 658 ) , NCI-H1819 (pulmonary) ( 351 ) , NCI-H1838 (pulmonary) ( 658 ) , NCI-H1975 (pulmonary) ( 25 , 134 , 188 , 342 , 686 ) , NCI-H23 (pulmonary) ( 195 , 490 ) , NCI-H292 (pulmonary) ( 188 , 242 , 288 ) , NCI-H3255 (pulmonary) ( 188 , 196 , 323 , 324 ) , NCI-H345 (pulmonary) ( 730 ) , NCI-H441 (pulmonary) ( 353 , 354 , 357 , 358 , 359 ) , NCI-H460 (pulmonary) ( 16 , 25 , 116 , 188 , 438 , 490 , 551 ) , NCI-H510 (pulmonary) ( 730 ) , NCI-H69 (pulmonary) ( 730 ) , NCI-H727 (epithelial) ( 30 ) , NCI-H929 (B lymphocyte) ( 64 ) , neuron-'brain, cerebellum' ( 758 ) , neuron-'brain, hippocampus' ( 240 , 827 ) , neutrophil ( 554 , 560 , 796 , 880 , 899 ) , NL-17 (intestinal) ( 864 ) , NMuMG (epithelial) ( 182 ) , NSCLC (pulmonary) ( 888 ) , OAW28 (ovarian) ( 31 ) , OCI/AML3 (myeloid) ( 47 ) , OK (renal) ( 548 , 600 ) , oocyte ( 69 , 223 ) , osteoblast-calvarium ( 635 , 722 ) , OV2008 (ovarian) ( 241 ) , ovarian ( 593 ) , ovary ( 362 , 476 , 756 ) , OvCa433 ( 121 ) , OVCAR3 (ovarian) ( 31 , 389 , 562 , 563 , 753 ) , OVCAR4 (ovarian) ( 590 , 756 ) , OVCAR5 (ovarian) ( 389 , 590 , 756 ) , P116 (T lymphocyte) ( 384 ) , PAE (endothelial) ( 74 , 332 , 364 , 484 , 678 , 707 , 884 , 904 ) , PANC-1 (pancreatic) ( 70 , 72 , 366 , 469 , 689 ) , pancreas ( 70 , 713 , 737 , 742 ) , pancreatic ( 264 ) , pancreatic acini ( 628 ) , PC-12 (chromaffin) ( 168 , 680 , 758 , 828 , 841 ) , PC3 (prostate cell) ( 15 , 42 , 84 , 91 , 98 , 197 , 206 , 235 , 271 , 296 , 426 , 463 , 464 , 465 , 471 , 514 , 551 , 644 , 655 , 711 , 717 , 791 , 843 , 864 , 879 , 916 ) , PC3 (prostate cell) [CD82 (human)] ( 644 ) , PC9-IR (pulmonary) ( 134 ) , PEO4 (ovarian) ( 590 ) , PEO6 (ovarian) ( 590 ) , platelet-blood ( 128 , 446 , 503 , 534 , 583 , 776 , 862 , 908 ) , PLC/PRF/5 (hepatic) ( 118 ) , prostate ( 498 , 752 ) , QGP-1 (endocrine) ( 30 ) , QZG (hepatic) ( 229 ) , Rat1 (fibroblast) ( 550 ) , RAW 264.7 (macrophage) ( 295 ) , RCC4 (renal) ( 470 ) , RD (muscle cell) ( 41 , 156 ) , Rh1 (bone cell) ( 520 ) , Rh13 (muscle cell) ( 789 ) , Rh18 (muscle cell) ( 520 , 789 ) , Rh30 (muscle cell) ( 41 , 156 , 520 , 544 , 789 ) , Rh4 (muscle cell) ( 789 ) , Rh41 ( 520 ) , Rh5 (muscle cell) ( 789 ) , RMF (fibroblast) ( 28 ) , RPMI-8226 (plasma cell) ( 17 ) , RPTE (epithelial) ( 813 ) , RWP1 (pancreatic) ( 190 ) , RWPE1 (prostate cell) ( 419 ) , Saos-2 (bone cell) ( 661 ) , SB2 (melanocyte) ( 427 ) , SCC12 (keratinocyte) ( 870 ) , Schwann ( 480 ) , SF767 (glial) ( 33 ) , SGC7901 (gastric) ( 149 ) , SH-SY5Y (neural crest) ( 247 , 260 , 278 , 515 , 539 , 587 , 606 , 643 , 680 , 758 , 785 , 827 , 829 , 852 , 874 , 876 ) , SHEP (neuron) ( 587 , 754 , 928 ) , SK-LMS-1 (muscle cell) ( 287 ) , SK-MEL-23 (melanocyte) ( 436 ) , SK-MEL2 (melanocyte) ( 427 ) , SK-MEL28 (melanocyte) ( 71 ) , SK-MEL5 (melanocyte) ( 427 ) , SK-N-MC (neural crest) ( 119 , 754 ) , SKBr3 (breast cell) ( 35 , 40 , 174 , 187 , 288 , 370 , 387 , 456 , 504 , 507 , 563 , 721 , 787 , 851 ) , SKBR7 (breast cell) ( 52 ) , skin ( 39 , 427 , 822 ) , SKNBE (neural crest) ( 587 ) , SKNSH (neural crest) ( 587 ) , SKOV-3 (ovarian) ( 54 , 68 , 150 , 241 , 296 , 339 , 369 , 389 , 590 , 593 , 667 , 756 , 812 , 836 , 867 ) , SKRC-44 (renal) ( 660 , 813 ) , SKRC-49 (renal) ( 813 ) , SN12C (renal) ( 175 ) , SNB-19 (glial) ( 649 , 665 ) , SNU-1 (gastric) ( 527 ) , SNU-484 (gastric) ( 513 ) , SNU-620 (gastric) ( 513 ) , SNU16Ad (gastric) ( 460 ) , SR-786 (T lymphocyte) ( 374 ) , SRB-1 (squamous) ( 810 ) , ST88-14 (neuron) ( 405 ) , SU-DHL1 (T lymphocyte) ( 374 ) , Su.86.86 (pancreatic) ( 20 , 70 ) , SUM149 (breast cell) ( 187 ) , SUM159 (breast cell) ( 187 , 533 ) , SUM190 (breast cell) ( 187 ) , SUP-M2 (T lymphocyte) ( 282 ) , SV40 ( 671 ) , SW-1573 (pulmonary) ( 188 , 529 ) , SW1353 ( 83 ) , SW1990 (pancreatic) ( 72 ) , SW48 (intestinal) ( 143 , 725 ) , SW480 (intestinal) ( 659 ) , SW620 (intestinal) ( 143 , 559 ) , SW684 ( 287 ) , SY5Y (neuron) ( 757 , 786 ) , synoviocyte-synovium ( 521 ) , T lymphocyte ( 60 ) , T lymphocyte-blood ( 262 , 521 , 547 , 556 , 572 , 597 , 816 ) , T/C-28a2 (chondrocyte) ( 341 ) , T24 (bladder cell) ( 279 , 502 , 626 ) , T47D (breast cell) ( 27 , 38 , 139 , 174 , 308 , 334 , 382 , 387 , 453 , 507 , 563 , 778 , 919 ) , T98G (glial) ( 139 , 259 , 314 , 611 , 761 , 875 ) , TF-1 (erythroid) ( 103 , 645 , 915 ) , THP1 (myeloid) ( 477 , 535 ) , thymus ( 315 ) , thyroid ( 708 , 828 ) , TPC-1 (thyroid cell) ( 708 ) , Tsu (prostate cell) ( 243 , 858 ) , U-118MG (glial) ( 33 ) , U-937 (myeloid) ( 467 , 530 , 645 , 751 , 811 ) , U251 (glial) ( 33 , 314 , 604 , 649 , 650 , 665 ) , U2OS (bone cell) ( 159 , 178 , 413 , 449 , 462 , 586 ) , U2OS (bone cell) [GR (human)] ( 698 ) , U373 MG (glial) ( 380 , 443 , 649 ) , U4A (fibroblast) ( 875 ) , U87MG (glial) ( 33 , 107 , 275 , 301 , 366 , 413 , 587 , 588 , 649 , 650 , 665 , 687 , 735 , 749 , 861 , 898 , 910 ) , U87MG (glial) [EGFR (human), transfection] ( 349 ) , UACC-257 (melanocyte) ( 427 ) , UCSD-354L (melanocyte) ( 427 ) , UI.wt (fibroblast) ( 837 ) , UMSCC1 (squamous) ( 194 , 313 ) , UMSCC11A (squamous) ( 313 ) , UMSCC11A (squamous) [YAP1 (human), transfection] ( 313 ) , UMSCC11B (squamous) ( 313 ) , UMSCC22A (squamous) ( 313 ) , UMSCC22B (squamous) ( 313 ) , UMSCC38 (squamous) ( 313 ) , UMSCC46 (squamous) ( 313 ) , UMSCC6 (squamous) ( 313 ) , UMSCC9 (squamous) ( 313 ) , UT-7 (myeloid) ( 192 , 512 ) , UT-7 (myeloid) [EPO (human), transfection] ( 913 ) , vascular smooth muscle cell ('muscle, smooth') ( 536 , 659 ) , VSMC ('muscle, smooth') ( 167 ) , VSMC-aorta ( 328 ) , WI-38 (fibroblast) ( 462 ) , WiDr (epithelial) ( 48 ) , WM-1552 (melanocyte) ( 427 ) , WM115 (melanocyte) ( 822 ) , WM1799 (melanocyte) ( 427 ) , WM2664 (melanocyte) ( 427 ) , WM3211 (melanocyte) ( 427 ) , WM35 (melanocyte) ( 427 , 506 , 623 ) , WM46 (melanocyte) ( 427 ) , WM793 ( 296 ) , ZR-75-1 (breast cell) ( 38 , 174 , 605 )

Upstream Regulation
Regulatory protein:
4E-BP1 (human) ( 510 ) , Ack (human) ( 77 , 419 ) , ACPP (human) ( 344 ) , AFAP1L2 (human) ( 459 ) , AFP (human) ( 118 ) , Akt1 (human) ( 5 , 114 , 223 , 255 , 278 , 296 , 482 , 483 , 522 , 585 , 640 , 813 , 851 , 853 , 854 , 910 ) , Akt2 (human) ( 133 , 255 , 483 ) , ALK (human) ( 861 ) , AMIGO2 (human) ( 79 ) , AMPKA1 (human) ( 343 , 596 ) , AMPKA2 (human) ( 678 ) , AR (human) ( 255 ) , ARAF (human) ( 598 ) , ATM (human) ( 714 ) , ATP6V1B2 (mouse) ( 599 ) , AurA (human) ( 460 ) , axin 1 (mouse) ( 240 ) , Bcr (human) ( 13 ) , beclin 1 (human) ( 80 ) , BMF (human) ( 208 ) , BRAF (human) ( 427 ) , Brk (human) ( 333 ) , BTG2 (human) ( 248 ) , Btk (human) ( 594 ) , CA9 (human) ( 660 ) , CAMKK1 (human) ( 853 ) , caveolin-1 (human) ( 156 ) , CCKBR (human) ( 614 ) , CD10 (human) ( 320 ) , CD133 (human) ( 96 ) , CD82 (human) ( 644 ) , CDC25B (human) ( 452 ) , CDC37 (human) ( 111 ) , CDK1 (human) ( 23 ) , CDK5 (human) ( 91 , 120 ) , CHKA (human) ( 478 ) , CHKB (human) ( 478 ) , CK1E (human) ( 154 ) , CPNE3 (human) ( 387 ) , CSF2RB (human) ( 777 ) , CXCR4 (human) ( 116 ) , CYP3A5 (human) ( 97 ) , CYR61 (human) ( 380 ) , DARPP-32 (human) ( 527 ) , DDIT4 (human) ( 699 ) , DDIT4L (human) ( 699 ) , DDX5 (human) ( 78 ) , DOK2 (human) ( 691 ) , DYRK2 (human) ( 27 ) , E4 (adenovirus) ( 773 ) , EFNA2 (human) ( 296 ) , EGFR (human) ( 448 , 458 , 632 , 640 ) , eNOS (mouse) ( 482 ) , Epac1 (human) ( 197 , 493 ) , Epiregulin (human) ( 248 ) , EPOR (human) ( 192 ) , ER-alpha (human) ( 251 , 375 ) , ER-beta (human) ( 579 ) , ERK1 (human) ( 576 , 578 ) , ERK2 (human) ( 221 , 576 , 578 ) , ERK5 (human) ( 364 ) , Etk (human) ( 183 ) , FAK (human) ( 559 ) , FHIT (human) ( 638 ) , FKBP5 (human) ( 9 , 255 ) , FOXO1A (human) ( 376 ) , FOXO3A (human) ( 174 ) , FRK (human) ( 449 ) , FRS2 (human) ( 615 ) , FSTL1 (mouse) ( 482 ) , G-alpha(q) (human) ( 477 ) , GAB2 (human) ( 492 ) , GAS6 (human) ( 19 ) , GHSR (human) ( 575 ) , girdin (human) ( 57 ) , GRB14 (human) ( 641 ) , GRB2 (human) ( 280 , 662 ) , GSK3A (human) ( 221 ) , GSK3B (human) ( 142 ) , HER2 (human) ( 174 , 632 , 633 ) , HER4 (human) ( 436 ) , HIF2A (human) ( 429 ) , HRas (human) ( 5 , 248 , 296 , 363 , 469 , 718 ) , HSP70 (human) ( 93 ) , HSP90A (human) ( 504 ) , IEX-1 (human) ( 578 ) , IGFBP3 (human) ( 438 ) , IKKB (human) ( 501 ) , IKKB (mouse) ( 352 ) , IL2RA (human) ( 572 ) , ILK (human) ( 363 , 514 , 650 , 659 , 689 , 767 , 781 , 784 , 916 ) , ILKAP (human) ( 890 ) , INPP4B (human) ( 48 ) , INPP5E (human) ( 865 ) , IRS1 (human) ( 780 ) , IRS2 (human) ( 185 ) , ITGA3 (human) ( 76 ) , JNK1 (human) ( 576 ) , JNK2 (human) ( 576 ) , KRas (human) ( 312 , 718 ) , LAPTM4B (human) ( 98 ) , Lck (human) ( 794 ) , LIMS1 (human) ( 784 ) , LKB1 (human) ( 490 , 508 ) , LKB1 (mouse) ( 69 ) , Lmr3 (human) ( 252 ) , LYN (human) ( 518 ) , MEK1 (human) ( 221 , 548 , 667 , 845 ) , Mer (mouse) ( 519 ) , MINK (human) ( 52 ) , MKK4 (human) ( 657 ) , MKK6 (human) ( 685 , 845 ) , MST2 (human) ( 369 ) , mTOR (human) ( 97 , 223 , 363 , 440 , 456 , 478 , 514 , 517 , 551 , 584 ) , MUC4 (human) ( 629 ) , MYO6 (human) ( 18 ) , N-WASP (human) ( 18 ) , NCK1 (mouse) ( 163 ) , NCK2 (mouse) ( 163 ) , NDFIP1 (human) ( 360 ) , NDFIP2 (human) ( 360 ) , NF1 (human) ( 598 ) , Notch 1 (human) ( 74 , 639 ) , NRas (human) ( 312 , 427 ) , NRG1 (human) ( 248 , 389 ) , OSBPL8 (mouse) ( 268 ) , OSBPL9 (human) ( 584 ) , osteopontin (human) ( 423 ) , p16-INK4A (human) ( 110 ) , P2X7 (human) ( 81 ) , P38A (human) ( 685 , 845 ) , p53 (human) ( 462 , 639 ) , PAK1 (rat) ( 483 ) , PAK2 (human) ( 483 ) , PARVA (human) ( 117 ) , PARVB (human) ( 733 ) , PBK (human) ( 195 ) , PCGF2 (human) ( 507 ) , PCTP (human) ( 185 ) , PDE4B (human) ( 493 ) , PDE4D (human) ( 493 ) , PDK1 (human) ( 718 , 844 ) , PDK1 (mouse) ( 902 ) , PDZK1 (human) ( 7 ) , PEAK1 (human) ( 173 ) , PHLDA3 (human) ( 462 ) , PHLPP (human) ( 296 , 366 , 569 ) , PHLPP2 (human) ( 366 , 569 ) , PI5PA (mouse) ( 654 ) , PIK3C2A (human) ( 54 , 472 , 476 ) , PIK3C2B (human) ( 236 ) , PIK3CA (human) ( 243 , 296 , 419 , 499 , 601 , 845 ) , PIK3CB (human) ( 363 ) , PIK3CD (human) ( 540 ) , PIK3CG (human) ( 748 ) , PIK3R1 (human) ( 15 , 667 ) , PIK3R2 (human) ( 14 ) , Pim1 (human) ( 49 , 464 ) , PINK1 (human) ( 272 ) , PIP3-E (human) ( 266 ) , PKCA (human) ( 330 , 430 ) , PKCB (human) ( 601 ) , PKCE (human) ( 335 ) , PKCT (human) ( 179 ) , PKN1 (human) ( 902 ) , PKN2 (human) ( 902 , 905 ) , PKR (human) ( 500 ) , PLCG2 (human) ( 594 ) , PPM1D (human) ( 101 ) , PPP1CA (human) ( 327 ) , PPP2CA (human) ( 399 , 523 ) , PPP2R2A (human) ( 56 , 58 ) , PPP2R5B (human) ( 578 ) , PPP2R5D (human) ( 578 ) , PRAS40 iso3 (human) ( 510 ) , PREX1 (human) ( 308 ) , PRICKLE1 (human) ( 52 ) , PRKD1 (human) ( 100 ) , PTEN (human) ( 169 , 191 , 312 , 476 , 508 , 580 , 582 , 586 , 794 , 854 , 898 , 910 , 911 , 916 ) , PTEN (mouse) ( 898 ) , PTGER2 (mouse) ( 341 ) , PTGER3 (mouse) ( 341 ) , PTPRJ (human) ( 473 ) , PTPRK (human) ( 96 ) , PXN iso2 (human) ( 408 ) , Pyk2 (human) ( 607 ) , QIK (human) ( 339 ) , RAC1 (human) ( 58 , 483 ) , RAP1A (human) ( 466 , 493 ) , RAP1B (human) ( 466 ) , RAP2A (human) ( 493 ) , Raptor (human) ( 440 , 517 , 551 ) , Raptor (mouse) ( 405 ) , RARRES2 (human) ( 421 ) , RASGRP3 (human) ( 107 ) , RBP1 (human) ( 709 ) , reelin (human) ( 64 ) , Ret (human) ( 336 , 459 , 828 ) , RHOA (human) ( 845 ) , RHOB (human) ( 58 ) , RICTOR (human) ( 38 , 45 , 61 , 97 , 197 , 207 , 243 , 312 , 331 , 440 , 456 , 463 , 478 , 506 , 514 , 517 , 551 ) , RUVBL1 (human) ( 181 ) , S6 (human) ( 745 ) , SGK1 (human) ( 728 ) , SHC3 (human) ( 841 ) , SHIP (human) ( 262 , 739 ) , SHIP-2 (mouse) ( 910 ) , SHP-1 (human) ( 794 ) , SHP-2 (human) ( 296 ) , SHPS1 (human) ( 349 ) , Sin1 (human) ( 456 ) , Sin1 (mouse) ( 162 ) , SLC1A5 (human) ( 555 ) , SMAD7 (human) ( 717 ) , Snail1 (human) ( 190 ) , SOCS3 (human) ( 528 ) , SPRY2 (human) ( 668 ) , Src (human) ( 191 , 473 , 522 , 624 , 626 , 667 , 794 ) , SRXN1 (human) ( 497 ) , ST3GAL5 (human) ( 105 ) , ST8SIA1 (human) ( 105 ) , STAT3 (mouse) ( 424 ) , Survivin (human) ( 411 ) , TACE (human) ( 632 ) , TBX2 (human) ( 41 ) , THEM2 (human) ( 185 ) , TNK1 (human) ( 385 ) , TRAF6 (human) ( 439 ) , TRAP (human) ( 126 ) , TrkB (human) ( 829 ) , TSC2 (human) ( 221 , 506 ) , ULK1 (human) ( 568 ) , USP49 (human) ( 20 ) , VCAM1 (human) ( 230 ) , VEGFR1 (human) ( 904 ) , VEGFR2 (human) ( 904 ) , YAP1 (human) ( 92 ) , ZFP57 (human) ( 104 )
Putative in vivo kinases:
AXL (human) ( 37 ) , IKKE (human) ( 228 ) , ILK (human) ( 805 , 812 , 879 , 918 ) , LRRK2 (human) ( 247 ) , Mer (human) ( 37 ) , mTOR (human) ( 711 ) , PDK1 (human) ( 864 ) , PIKFYVE (human) ( 826 ) , PRKD1 (human) ( 844 ) , TBK1 (human) ( 277 )
Kinases, in vitro:
DNAPK (human) ( 454 ) , ILK (human) ( 879 ) , LRRK2 (human) ( 247 ) , MAPKAPK2 (human) ( 926 ) , mTOR (human) ( 139 , 162 , 207 , 217 , 317 , 363 , 711 ) , mTOR (mouse) ( 199 ) , PDK1 (human) ( 864 ) , PKCA (human) ( 908 ) , PKCB (human) ( 908 ) , TBK1 (human) ( 295 )
Putative upstream phosphatases:
PHLPP (human) ( 695 ) , PHLPP2 (human) ( 569 ) , PPP1CA (human) ( 270 , 787 ) , PPP2CA (human) ( 447 )
Phosphatases, in vitro:
PHLPP (human) ( 695 ) , PHLPP2 (human) ( 569 ) , PPP1CA (human) ( 787 ) , PTEN (human) ( 31 )
Treatments:
1-azakenpaullone ( 142 ) , 1-methyladenine ( 223 ) , 14,15-DHETs ( 284 ) , 14,15-EETs ( 284 ) , 15-epi-LXA4 ( 554 ) , 17-beta-estradiol ( 149 ) , 2-AG ( 128 ) , 2-deoxyglucose ( 329 , 438 , 490 , 833 ) , 3-aminobenzamide ( 602 ) , 4-DAMP ( 198 , 883 ) , 4-HT ( 90 , 144 , 451 , 522 , 539 , 602 , 750 , 771 , 844 ) , 5(S)-HETE ( 835 ) , 5-cholesten-5-beta-ol ( 383 ) , 5-thio-glucose ( 833 ) , 6-Bnz cAMP ( 136 ) , 6-OHDA ( 758 ) , 8-CPT-2Me-cAMP ( 197 ) , 8-Rp-cAMP ( 634 ) , A-443654 ( 481 , 551 , 559 , 600 ) , A-674563 ( 287 ) , A23187 ( 607 , 825 ) , A740003 ( 81 ) , acadesine ( 136 , 172 , 447 , 596 , 801 ) , actinomycin_D ( 367 ) , activin ( 201 ) , ADA ( 560 ) , adiponectin ( 447 , 788 ) , adriamycin ( 119 , 462 ) , AEE788 ( 342 , 387 ) , afatinib ( 134 ) , AG1024 ( 778 ) , AG1296 ( 778 ) , AG1478 ( 121 , 272 , 349 , 383 , 401 , 475 , 607 , 680 , 720 , 778 , 850 ) , AG2037 ( 16 ) , AG490 ( 512 , 528 , 835 ) , AH6809 ( 175 , 341 ) , Akt-I-1 ( 399 , 548 , 724 ) , Akt-I-1,2 ( 370 , 430 , 724 ) , Akt_inhibitor_VIII ( 278 , 334 , 373 , 460 ) , Akt_inhibitor_X ( 313 ) , aldosterone ( 630 ) , aloe-emodin ( 35 ) , alpelisib ( 30 , 49 ) , alpha-mangostin ( 300 ) , alphaIR3 ( 534 , 789 ) , amino_acid_starvation ( 135 , 623 ) , amino_acids ( 404 , 510 , 669 , 676 , 770 ) , aminoflavone ( 552 ) , anastrozole ( 375 ) , androsterone ( 375 ) , angiopoietin-1 ( 702 , 779 , 907 , 927 ) , angiopoietin-2 ( 702 , 907 ) , angiotensin ( 762 ) , angiotensin-(1-7) ( 592 ) , anisomycin ( 770 ) , anthrax_toxin ( 535 ) , anti-Akt1 ( 696 ) , anti-CD11a ( 597 ) , anti-CD150 ( 727 ) , anti-CD28 ( 597 ) , anti-CD3 ( 262 , 384 , 547 , 816 , 911 ) , anti-CD3/CD28 ( 572 , 732 ) , anti-CD44 ( 597 ) , anti-CD53 ( 818 ) , anti-CD8 ( 546 ) , anti-FcRII ( 899 ) , anti-FcRIII ( 899 ) , anti-HER2 ( 150 , 582 , 721 , 851 ) , anti-HLA ( 517 ) , anti-ICAM-2 ( 868 ) , anti-ICOS ( 597 ) , anti-IgD ( 163 ) , anti-IGF1R ( 438 ) , anti-IgM ( 163 , 601 ) , anti-integrin_alpha9beta1 ( 296 ) , anti-PDGFR ( 489 , 778 ) , anti-TCR ( 580 ) , anti-VE-cadherin ( 773 ) , anti-VEGF ( 782 ) , APC ( 467 ) , apelin ( 731 ) , apoA-I ( 766 ) , apocynin ( 75 ) , apyrase ( 534 ) , AR-A014418 ( 142 ) , arachidonic_acid ( 880 ) , ARC ( 525 ) , ARC69331-MX ( 534 ) , As2O3 ( 545 ) , atiprimod ( 595 ) , atorvastatin ( 596 , 871 ) , ATP ( 475 , 809 ) , atropine ( 883 ) , AZ1060120 ( 81 ) , AZD6094 ( 88 ) , AZD8055 ( 45 , 86 , 413 ) , BAPTA-AM ( 600 , 607 , 655 , 776 , 871 , 878 , 894 , 908 , 914 ) , BDNF ( 757 ) , bicyclol ( 34 ) , bisindolylmaleimide ( 508 , 534 , 584 , 601 , 908 ) , black_tea_polyphenols ( 685 ) , BN52021 ( 825 ) , BNTX ( 12 ) , Boc-D-FMK ( 806 ) , bombesin ( 628 ) , bortezomib ( 373 ) , BPDE ( 607 ) , bpV ( 787 ) , BQ ( 795 ) , BQ-123 ( 720 ) , BQ-788 ( 720 ) , bradykinin ( 884 , 889 , 894 ) , BRL37344 ( 642 ) , butaprost ( 175 ) , BzATP ( 81 ) , C2-ceramide ( 813 ) , C3_toxin ( 845 ) , C5a ( 765 ) , C5b-9 ( 627 ) , C6-ceramide ( 54 , 915 ) , Ca(2+) ( 843 , 914 ) , caffeine ( 275 , 278 ) , calpeptin ( 614 ) , calphostin_C ( 398 ) , calyculin_A ( 296 , 583 , 634 , 655 , 787 , 827 , 871 , 915 ) , cAMP_analog ( 480 , 493 , 700 ) , canertinib ( 515 ) , cangrelor ( 776 ) , carbachol ( 198 , 628 , 807 , 883 ) , carmustine ( 604 ) , CAY10399 ( 560 ) , Cbz-B3A ( 63 ) , CCCP ( 785 ) , CCL5 ( 457 ) , CDDO-Me ( 494 ) , celecoxib ( 849 ) , cell_adhesion ( 665 ) , ceramide ( 809 , 918 ) , CGS_21680 ( 560 ) , chelerythrine ( 398 ) , cholesterol_oxidase ( 383 ) , ciclosporin ( 259 , 655 , 680 , 734 , 827 ) , cisplatin ( 121 , 381 , 677 , 813 ) , CK37 ( 246 ) , CML ( 526 ) , colforsin ( 446 , 480 , 493 , 548 , 560 , 634 , 893 ) , collagen ( 644 , 862 ) , collagen XIX (NC1 domain) ( 71 ) , compound_7 ( 276 ) , compound_C ( 447 , 596 , 678 ) , conditioned medium ( 47 , 140 ) , convulxin ( 862 ) , coumermycin ( 904 ) , CPA ( 914 ) , crizotinib ( 187 , 245 , 282 ) , CRP ( 446 ) , CSD_peptide ( 871 ) , CTGF ( 621 , 719 ) , culturing_of_cells ( 601 , 742 ) , CV3988 ( 825 ) , CXCL12 ( 594 , 601 ) , cyclic_stretch ( 720 ) , cycloheximide ( 226 ) , D609 ( 809 ) , dactolisib ( 109 , 160 , 255 , 499 ) , DAMGO ( 922 ) , dasatinib ( 103 , 134 , 194 , 296 ) , decorin ( 872 ) , deoxygenation ( 151 ) , depolarization ( 606 , 680 ) , derivative-2 ( 132 ) , dexamethasone ( 545 , 566 , 722 ) , DHC ( 918 ) , DHPG ( 581 ) , dimethylfumarate ( 122 ) , DMNQ ( 795 ) , DMS ( 813 ) , DMSO ( 499 , 522 , 559 ) , DNP ( 584 ) , dronabinol ( 529 , 622 ) , duvelisib ( 47 ) , E-cadherin-Fc ( 60 ) , edelfosine ( 600 ) , EF24 ( 543 ) , eflornithine ( 481 ) , EGCG ( 271 , 797 ) , EGF ( 10 , 18 , 54 , 114 , 171 , 221 , 245 , 248 , 272 , 287 , 294 , 307 , 308 , 333 , 334 , 342 , 351 , 360 , 369 , 370 , 381 , 391 , 401 , 417 , 437 , 458 , 468 , 487 , 488 , 492 , 515 , 529 , 537 , 569 , 607 , 617 , 624 , 625 , 628 , 632 , 633 , 649 , 650 , 654 , 660 , 662 , 691 , 729 , 733 , 744 , 756 , 778 , 781 , 809 , 820 , 837 , 841 , 843 , 845 , 850 , 863 , 876 , 893 , 896 , 903 ) , EGTA ( 198 , 600 , 843 ) , endostatin ( 860 ) , endothelin ( 845 ) , englerin_A ( 179 ) , enzalutamide ( 255 ) , enzastaurin ( 513 ) , ephrin_A1 ( 296 , 443 ) , ephrin_A4 ( 296 ) , eplerenone ( 630 ) , Epo ( 192 , 472 , 512 , 578 , 808 , 913 ) , equol ( 618 ) , erlotinib ( 188 , 351 , 438 , 697 ) , estradiol ( 373 , 382 , 392 , 406 , 417 , 442 , 579 , 590 , 602 , 605 , 613 , 678 , 747 , 869 , 906 ) , estrogen_deprivation ( 690 , 802 ) , ethanol ( 21 , 807 ) , etoposide ( 677 , 813 ) , ETS ( 36 ) , exercise ( 612 , 652 , 692 ) , exercise training ( 289 ) , factor_XII ( 361 ) , faslodex ( 453 , 685 , 869 ) , fasting ( 148 ) , fedratinib ( 512 ) , fetal growth restriction ( 141 ) , FGF1 ( 178 , 334 , 473 , 615 ) , FGF2 ( 628 , 643 , 668 , 832 ) , FGF9 ( 168 ) , fibronectin ( 164 , 644 , 658 , 859 , 890 , 916 ) , Filipin ( 383 ) , fingolimod ( 44 , 811 ) , fipronil ( 260 ) , FK506 ( 680 , 827 ) , FL ( 44 ) , flagellin ( 546 ) , fluid_shear_stress ( 83 , 341 , 734 , 866 , 891 ) , fluvastatin ( 400 ) , FMK-MEA ( 143 ) , fMLP ( 560 , 793 , 880 , 899 ) , fructose ( 124 ) , fumonisin_B1 ( 809 , 813 ) , gallamine triethiodide ( 883 ) , ganglioside ( 870 ) , Gas6 ( 519 , 867 ) , gastrin ( 420 , 614 ) , GDNF ( 336 , 841 ) , gefitinib ( 196 , 608 , 632 , 633 , 653 , 686 , 701 , 787 ) , geldanamycin ( 504 , 626 , 688 , 787 , 871 , 877 ) , genistein ( 667 , 773 , 796 , 914 ) , GF109203X ( 437 , 446 , 731 , 776 , 825 , 883 ) , GGTI-2418 ( 450 ) , GH ( 148 ) , ghrelin ( 227 , 477 , 575 ) , ginsenoside-Rg1 ( 603 ) , glabridin ( 213 ) , glucagon ( 136 ) , glucose ( 162 , 496 , 736 , 833 ) , glucose_oxidase ( 433 ) , glucose_starvation ( 329 ) , glycyrrhizinic_acid ( 29 ) , GM-CSF ( 103 , 915 ) , Go_6976 ( 584 , 908 ) , GSK2334470 ( 17 , 84 ) , GSK690693 ( 115 ) , GTX-155 ( 534 ) , GTX-221 ( 534 ) , H-89 ( 136 , 341 , 480 , 508 , 560 , 700 ) , H2O2 ( 340 , 491 , 508 , 585 , 591 , 651 , 819 , 897 ) , HA-1077 ( 743 ) , HB-EGF ( 307 ) , HDL ( 814 ) , heart failure ( 474 ) , heat_shock ( 769 , 785 , 864 ) , herbimycin_A ( 667 , 731 , 794 ) , Herceptin/rGel ( 150 ) , heregulin ( 201 , 308 , 387 , 417 , 419 , 557 , 579 , 590 , 615 , 632 , 787 ) , HGF ( 97 , 114 , 138 , 164 , 245 , 249 , 380 , 628 , 701 , 774 , 859 , 900 ) , high_glucose ( 29 , 123 ) , histamine ( 863 ) , HKI-357 ( 686 ) , HNMPA(AM)3 ( 435 ) , honokiol DCA ( 62 ) , HU-210 ( 823 ) , hypoxia ( 429 , 445 , 803 , 833 , 897 ) , hypoxia/reoxygenation ( 657 ) , ibuprofen ( 32 ) , IC87114 ( 534 , 560 ) , ICAM-2 ( 868 ) , IFN-beta ( 837 ) , IFN-gamma ( 875 ) , IGF-1 ( 21 , 80 , 114 , 160 , 162 , 167 , 201 , 271 , 312 , 320 , 334 , 363 , 370 , 373 , 375 , 398 , 417 , 438 , 439 , 446 , 468 , 478 , 520 , 534 , 540 , 553 , 563 , 587 , 602 , 628 , 666 , 679 , 697