Tyr494
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Home > Phosphorylation Site Page: > Tyr494  -  PTHR (human)

Site Information
ARsGsssySyGPMVS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 28764913

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HES-3 ('stem, embryonic') ( 2 ) , osteoblast-calvarium ( 1 )

Upstream Regulation
Putative in vivo kinases:
IGF1R (human) ( 1 )

Downstream Regulation
Effects of modification on PTHR:
intracellular localization ( 1 )
Effects of modification on biological processes:
cell differentiation, induced ( 1 ) , cytoskeletal reorganization ( 1 )

References 

1

Qiu T, et al. (2018) IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition. Bone Res 6, 5
29507819   Curated Info

2

Ding VM, et al. (2011) Tyrosine phosphorylation profiling in fgf-2 stimulated human embryonic stem cells. PLoS One 6, e17538
21437283   Curated Info