Thr607
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Home > Phosphorylation Site Page: > Thr607  -  Kv4.2 (rat)

Site Information
IPtPPVTtPEGDDRP   SwissProt
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 457612

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 4 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
'brain, hippocampus' ( 1 , 2 ) , CHO (fibroblast) ( 4 )

Upstream Regulation
Kinases, in vitro:
ERK1 (human) ( 3 ) , ERK2 (human) ( 3 )
Treatments:
PG 97-269 ( 1 ) , TBS ( 1 , 2 )

Downstream Regulation
Effects of modification on biological processes:
neural plasticity ( 1 )

References 

1

Caulino-Rocha A, Rodrigues NC, Ribeiro JA, Cunha-Reis D (2022) Endogenous VIP VPAC Receptor Activation Modulates Hippocampal Theta Burst Induced LTP: Transduction Pathways and GABAergic Mechanisms. Biology (Basel) 11
35625355   Curated Info

2

Rodrigues NC, et al. (2021) Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited. Eur J Neurosci 54, 5272-5292
34251729   Curated Info

3

Schrader LA, et al. (2009) Kv4.2 is a locus for PKC and ERK/MAPK cross-talk. Biochem J 417, 705-15
18795890   Curated Info

4

Yuan LL, et al. (2006) Acceleration of K+ channel inactivation by MEK inhibitor U0126. Am J Physiol Cell Physiol 290, C165-71
16135544   Curated Info