Thr602

Site Information
TAIISIPtPPVTtPE SwissProt
Blast this site against: NCBI SwissProt PDB
Site Group ID: 457611

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 4 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:	'brain, hippocampus' ( 1 , 2 ) , CHO (fibroblast) ( 4 )

Upstream Regulation
Kinases, in vitro:	ERK1 (human) ( 3 ) , ERK2 (human) ( 3 )
Treatments:	PG 97-269 ( 1 ) , TBS ( 1 , 2 )

References
1	Caulino-Rocha A, Rodrigues NC, Ribeiro JA, Cunha-Reis D (2022) Endogenous VIP VPAC Receptor Activation Modulates Hippocampal Theta Burst Induced LTP: Transduction Pathways and GABAergic Mechanisms. Biology (Basel) 11 35625355 Curated Info
2	Rodrigues NC, et al. (2021) Hippocampal CA1 theta burst-induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited. Eur J Neurosci 54, 5272-5292 34251729 Curated Info
3	Schrader LA, et al. (2009) Kv4.2 is a locus for PKC and ERK/MAPK cross-talk. Biochem J 417, 705-15 18795890 Curated Info
4	Yuan LL, et al. (2006) Acceleration of K+ channel inactivation by MEK inhibitor U0126. Am J Physiol Cell Physiol 290, C165-71 16135544 Curated Info