Ser338
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Home > Phosphorylation Site Page: > Ser338  -  SREBP-1 (human)

Site Information
IEkRYRSsINDkIIE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 458357

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HepG2 (hepatic) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Kinases, in vitro:
PKACA (human) ( 1 )
Treatments:
colforsin ( 1 ) , okadaic_acid ( 1 )

Downstream Regulation
Effects of modification on SREBP-1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
SREBP-1 (human) ( 1 )

References 

1

Lu M, Shyy JY (2006) Sterol regulatory element-binding protein 1 is negatively modulated by PKA phosphorylation. Am J Physiol Cell Physiol 290, C1477-86
16381800   Curated Info

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