Ser582
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.8.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser582  -  PIK3CG (human)

Site Information
LWHFRYEsLKHPKAY   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 28702402

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , BMMC (mast) ( 1 )

Upstream Regulation
Regulatory protein:
PIK3R6 (human) ( 1 )
Putative in vivo kinases:
PKCB (human) ( 1 )
Kinases, in vitro:
PKCB (human) ( 1 )
Treatments:
adenosine ( 1 ) , antibody ( 1 ) , BAPTA-AM ( 1 ) , EDTA ( 1 ) , Go_6976 ( 1 ) , Go_6983 ( 1 ) , IgE ( 1 ) , phorbol_ester ( 1 ) , PKC412 ( 1 ) , thapsigargin ( 1 )

Downstream Regulation
Effects of modification on PIK3CG:
enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )
Inhibit interaction with:
PIK3R6 (human) ( 1 )

References 

1

Walser R, et al. (2013) PKCβ Phosphorylates PI3Kγ to Activate It and Release It from GPCR Control. PLoS Biol 11, e1001587
23824069   Curated Info

PhosphoSitePlus® is a registered trademark of Cell Signaling Technology.
Use of PSP data is subject to a formal license agreement. Learn more

©2003-2025 Cell Signaling Technology, Inc.