Tyr259
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Home > Phosphorylation Site Page: > Tyr259  -  TGFBR2 (human)

Site Information
KGRFAEVykAKLkQN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2869604

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
TGFBR2 (human) ( 2 )

Downstream Regulation
Effects of modification on TGFBR2:
enzymatic activity, induced ( 2 )
Effects of modification on biological processes:
transcription, altered ( 2 )

References 

1

Chiang TA, et al. (2010) Hyperosmolarity enhanced susceptibility to renal tubular fibrosis by modulating catabolism of type I transforming growth factor-beta receptors. J Cell Biochem 109, 663-71
20091742   Curated Info

2

Lawler S, et al. (1997) The type II transforming growth factor-beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues. J Biol Chem 272, 14850-9
9169454   Curated Info