Thr428

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Home > Phosphorylation Site Page: > Thr428 - DRD1 (rat)

Site Information
sVILDYDtDVsLEKI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 458339

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:	GRK4 (human) ( 1 )
Treatments:	dopamine ( 1 )

Downstream Regulation
Effects of modification on DRD1:	intracellular localization ( 1 ) , receptor desensitization, altered ( 1 )

References
1	Rankin ML, et al. (2006) The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4. Mol Pharmacol 69, 759-69 16338988 Curated Info

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