Thr11
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Home > Phosphorylation Site Page: > Thr11  -  TRPC3 iso3 (human)

Site Information
SPSLRRMtVMREKGR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 458335

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) [PKG1 (human)] ( 2 ) , 293 (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKG1 (human) ( 1 , 2 )
Kinases, in vitro:
PKG1 (human) ( 2 )
Treatments:
KT5823 ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on TRPC3 iso3:
activity, inhibited ( 1 , 2 )

References 

1

Kwan HY, Huang Y, Yao X (2006) Protein kinase C can inhibit TRPC3 channels indirectly via stimulating protein kinase G. J Cell Physiol 207, 315-21
16331690   Curated Info

2

Kwan HY, Huang Y, Yao X (2004) Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G. Proc Natl Acad Sci U S A 101, 2625-30
14983059   Curated Info

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