Ser158
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Home > Phosphorylation Site Page: > Ser158  -  Lck (human)

Site Information
FLIREsEstAGsFSL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447817

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 4 ) , [32P] bio-synthetic labeling ( 4 ) , electrophoretic mobility shift ( 4 ) , mass spectrometry ( 1 , 2 , 3 ) , peptide sequencing ( 4 ) , phosphopeptide mapping ( 4 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
GF109203X ( 4 ) , phorbol_ester ( 4 )

References 

1

Guo A (2011) CST Curation Set: 11888; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P
Curated Info

2

Mayya V, et al. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal 2, ra46
19690332   Curated Info

3

Possemato A (2008) CST Curation Set: 3726; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

4

Soula M, et al. (1993) Anti-CD3 and phorbol ester induce distinct phosphorylated sites in the SH2 domain of p56lck. J Biol Chem 268, 27420-7
8262984   Curated Info