Tyr451
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Home > Phosphorylation Site Page: > Tyr451  -  RASA1 (mouse)

Site Information
TVDGKEIyNTIRRKT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449959

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) ( 3 ) , MEF (fibroblast) [PTP1B (mouse), homozygous knockout] ( 3 ) , RAW 264.7 (macrophage) ( 1 ) , SYF (fibroblast) [Src (mouse), transfection] ( 2 )

Upstream Regulation
Regulatory protein:
PTP1B (mouse) ( 3 )
Phosphatases, in vitro:
PTP1B (mouse) ( 3 )
Treatments:
PDGF ( 3 )

References 

1

Pinto SM, et al. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-44
25367039   Curated Info

2

Ferrando IM, et al. (2012) Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomics. Mol Cell Proteomics 11, 355-69
22499769   Curated Info

3

Mertins P, et al. (2008) Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics. Mol Cell Proteomics 7, 1763-77
18515860   Curated Info