Lys252
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Home > Acetylation Site Page: > Lys252  -  FLI1 (human)

Site Information
GGAQTISkNTEQRPQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 28108001

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 ) , Ewing's sarcoma ( 1 )
Relevant cell line - cell type - tissue:
COS7 (fibroblast) ( 1 ) , TC-32 ( 1 )

Upstream Regulation
Treatments:
trichostatin_A ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Schlottmann S, et al. (2012) Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity. Front Oncol 2, 107
22973553   Curated Info

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