Thr52
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr52  -  MVP (human)

Site Information
FAPMRMVtVPPRHyC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 28102700

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
hepatocellular carcinoma ( 1 )
Relevant cell line - cell type - tissue:
HCC (hepatic) ( 1 ) , HEK293T (epithelial) ( 1 ) , QGY-7703 (hepatic) ( 1 )

Upstream Regulation
Treatments:
bleomycin ( 1 )

Downstream Regulation
Effects of modification on MVP:
activity, inhibited ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
DNA repair, induced ( 1 )
Induce interaction with:
14-3-3 epsilon (human) ( 1 )

References 

1

Tang S, Bai C, Yang P, Chen X (2013) 14-3-3ε Boosts Bleomycin-induced DNA Damage Response by Inhibiting the Drug-resistant Activity of MVP. J Proteome Res 12, 2511-24
23590642   Curated Info