Ser286

Site Information
LHDRLRQsLRsERNN SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 28076401

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:	'3T3-L1, differentiated' (adipocyte) ( 2 ) , 3T3 (fibroblast) ( 1 ) , RPM-MC (melanocyte) ( 1 )

References
1	Parra LM, et al. (2015) Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44. Mol Cell Biol 35, 3381-95 26217011 Curated Info
2	Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6 26060331 Curated Info