Ser175
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Home > Phosphorylation Site Page: > Ser175  -  p27Kip1 (mouse)

Site Information
NRtEENVsDGsPNAG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 28058801

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry (in vitro) ( 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Disease tissue studied:
breast cancer ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
IKKA (mouse) ( 2 )

Downstream Regulation
Effects of modification on p27Kip1:
phosphorylation ( 2 )

References 

1

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

2

Zhang W, et al. (2013) A NIK-IKK╬▒ Module Expands ErbB2-Induced Tumor-Initiating Cells by Stimulating Nuclear Export of p27/Kip1. Cancer Cell 23, 647-59
23602409   Curated Info