Tyr54
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Home > Phosphorylation Site Page: > Tyr54  -  ARRB1 (rat)

Site Information
yLKERRVyVTLTCAF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 458023

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )
Kinases, in vitro:
Src (human) ( 1 )
Treatments:
isoproterenol ( 1 )

Downstream Regulation
Effects of modification on ARRB1:
molecular association, regulation ( 1 ) , receptor internalization, altered ( 1 )
Inhibit interaction with:
AP3M1 (mouse) ( 1 )

References 

1

Marion S, et al. (2007) N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins. J Biol Chem 282, 18937-44
17456469   Curated Info