Ser379
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.1.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser379  -  NFE2L1 (human)

Site Information
SQDFLLFsPEVESLP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27971902

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , SH-SY5Y (neural crest) ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 1 )
Kinases, in vitro:
GSK3B (human) ( 1 )

Downstream Regulation
Effects of modification on NFE2L1:
protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 )

References 

1

Biswas M, et al. (2013) Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1. Exp Cell Res 319, 1922-31
23623971   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.