Lys418

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Home > Sumoylation Site Page: > Lys418 - SREBP-1 (human)

Site Information
DVLMEGVkTEVEDTL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 2793924

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , CHO (fibroblast) ( 1 ) , COS (fibroblast) ( 1 ) , HeLa (cervical) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	transcription, inhibited ( 1 )

References
1	Hirano Y, et al. (2003) Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway. J Biol Chem 278, 16809-19 12615929 Curated Info

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