Ser43
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Home > Phosphorylation Site Page: > Ser43  -  p63 (human)

Site Information
yRSTMSQsTQtNEFL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27937107

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
IKKB (human) ( 1 )

Downstream Regulation
Effects of modification on p63:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
p300 (human) ( 1 )

References 

1

Liao JM, et al. (2013) IκB kinase β (IKKβ) inhibits p63 isoform γ (TAp63γ) transcriptional activity. J Biol Chem 288, 18184-93
23589370   Curated Info