Thr566
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr566  -  HIPK2 (human)

Site Information
DTVNQSktPFITHVA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27732205

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
adriamycin ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on HIPK2:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
cell growth, inhibited ( 1 )

References 

1

Verdina A, et al. (2017) HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation. Oncotarget 8, 16744-16754
28060750   Curated Info