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Home > Ubiquitylation Site Page: > Lys394  -  CTNNB1 (human)

Site Information
NLSDAAtkQEGMEGL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27850504

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on CTNNB1:
protein stabilization ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
breast adenocarcinoma ( 1 )



Gerard B, et al. (2012) Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin. Biochim Biophys Acta 1823, 1686-96
22705350   Curated Info