Tyr540
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.1.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr540  -  THEMIS (human)

Site Information
EEITEEQyyMMRRYE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27806313

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
leukemia ( 1 ) , T cell leukemia ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , Jurkat (T lymphocyte) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Lck (human) ( 1 ) , ZAP70 (human) ( 1 )
Kinases, in vitro:
Lck (human) ( 1 ) , ZAP70 (human) ( 1 )
Treatments:
PP2 ( 1 )

References 

1

Paster W, et al. (2013) GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol 190, 3749-56
23460737   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.