Tyr174
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Home > Phosphorylation Site Page: > Tyr174  -  THEMIS (human)

Site Information
LsQEGEFyECEDERI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27806311

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
leukemia ( 1 ) , T cell leukemia ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
Lck (human) ( 1 ) , ZAP70 (human) ( 1 )

References 

1

Paster W, et al. (2013) GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol 190, 3749-56
23460737   Curated Info