Lys146
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Home > Sumoylation Site Page: > Lys146  -  TR-beta1 (mouse)

Site Information
LHPSYSCkYEGKCII   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27490403

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
gestational cancer ( 1 ) , gestational trophoblastic choriocarcinoma ( 1 )
Relevant cell line - cell type - tissue:
JEG-3 (uterine) ( 1 )

Downstream Regulation
Effects of modification on TR-beta1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )

References 

1

Ke S, et al. (2021) Thyroid hormone receptor β sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight 6
34237030   Curated Info

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