Ser344
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Home > Phosphorylation Site Page: > Ser344  -  Myc (mouse)

Site Information
AkRAKLDsGRVLKQI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2750300

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 ) , chronic myelogenous leukemia ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , K562 (erythroid) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Pim1 (human) ( 1 ) , Pim2 (human) ( 1 )
Kinases, in vitro:
Pim1 (human) ( 1 ) , Pim2 (human) ( 1 )

Downstream Regulation
Effects of modification on Myc:
protein stabilization ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 1 ) , transcription, induced ( 1 )

References 

1

Zhang Y, Wang Z, Li X, Magnuson NS (2008) Pim kinase-dependent inhibition of c-Myc degradation. Oncogene 27, 4809-19
18438430   Curated Info

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