Thr305
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Home > O-GlcNAc Site Page: > Thr305  -  NFkB-p65 (human)

Site Information
IEEKRKRtyEtFksI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27490900

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 1 )

References 

1

Ma Z, Chalkley RJ, Vosseller K (2017) Hyper-O-GlcNAcylation activates nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling through interplay with phosphorylation and acetylation. J Biol Chem 292, 9150-9163
28416608   Curated Info

2

Allison DF, et al. (2012) Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-κB acetylation and transcription. Proc Natl Acad Sci U S A 109, 16888-93
23027940   Curated Info