Thr14
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Site Information
VEkIGEGtyGVVykA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447738
Available spectra:  5 CST
Associated spectra:  2 CST

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1456 , 1457 ) , flow cytometry ( 29 ) , immunoprecipitation ( 1 , 29 ) , mass spectrometry ( 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 14 , 15 , 16 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 , 167 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 , 187 , 188 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 , 212 , 213 , 214 , 215 , 216 , 217 , 218 , 219 , 220 , 221 , 222 , 223 , 224 , 225 , 226 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 248 , 249 , 250 , 251 , 252 , 253 , 254 , 255 , 256 , 257 , 258 , 259 , 260 , 261 , 262 , 263 , 264 , 265 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 278 , 279 , 280 , 281 , 282 , 283 , 284 , 285 , 286 , 287 , 288 , 289 , 290 , 291 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 299 , 300 , 301 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 315 , 316 , 317 , 318 , 319 , 320 , 321 , 322 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 339 , 340 , 341 , 342 , 343 , 344 , 345 , 346 , 347 , 348 , 349 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 357 , 358 , 359 , 360 , 361 , 362 , 363 , 364 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 375 , 376 , 377 , 378 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 392 , 393 , 394 , 395 , 396 , 397 , 398 , 399 , 400 , 401 , 402 , 403 , 404 , 405 , 406 , 407 , 408 , 409 , 410 , 411 , 412 , 413 , 414 , 415 , 416 , 417 , 418 , 419 , 420 , 421 , 422 , 423 , 424 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 434 , 435 , 436 , 437 , 438 , 439 , 440 , 441 , 442 , 443 , 444 , 445 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 453 , 454 , 455 , 456 , 457 , 458 , 459 , 460 , 461 , 462 , 463 , 464 , 465 , 466 , 467 , 468 , 469 , 470 , 471 , 472 , 473 , 474 , 475 , 476 , 477 , 478 , 479 , 480 , 481 , 482 , 483 , 484 , 485 , 486 , 487 , 488 , 489 , 490 , 491 , 492 , 493 , 494 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 517 , 518 , 519 , 520 , 521 , 522 , 523 , 524 , 525 , 526 , 527 , 528 , 529 , 530 , 531 , 532 , 533 , 534 , 535 , 536 , 537 , 538 , 539 , 540 , 541 , 542 , 543 , 544 , 545 , 546 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 555 , 556 , 557 , 558 , 559 , 560 , 561 , 562 , 563 , 564 , 565 , 566 , 567 , 568 , 569 , 570 , 571 , 572 , 573 , 574 , 575 , 576 , 577 , 578 , 579 , 580 , 581 , 582 , 583 , 584 , 585 , 586 , 587 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 605 , 606 , 607 , 608 , 609 , 610 , 611 , 612 , 613 , 614 , 615 , 616 , 617 , 618 , 619 , 620 , 621 , 622 , 623 , 624 , 625 , 626 , 627 , 628 , 629 , 630 , 631 , 632 , 633 , 634 , 635 , 636 , 637 , 638 , 639 , 640 , 641 , 642 , 643 , 644 , 645 , 646 , 647 , 648 , 649 , 650 , 651 , 652 , 653 , 654 , 655 , 656 , 657 , 658 , 659 , 660 , 661 , 662 , 663 , 664 , 665 , 666 , 667 , 668 , 669 , 670 , 671 , 672 , 673 , 674 , 675 , 676 , 677 , 679 , 680 , 681 , 682 , 683 , 684 , 685 , 686 , 687 , 688 , 689 , 690 , 691 , 692 , 693 , 694 , 695 , 696 , 697 , 698 , 699 , 700 , 701 , 702 , 703 , 704 , 705 , 706 , 707 , 708 , 709 , 710 , 711 , 712 , 713 , 714 , 715 , 716 , 717 , 718 , 719 , 720 , 721 , 722 , 723 , 724 , 725 , 726 , 727 , 728 , 729 , 730 , 731 , 732 , 733 , 734 , 735 , 736 , 737 , 738 , 739 , 740 , 741 , 742 , 743 , 744 , 745 , 746 , 747 , 748 , 749 , 750 , 751 , 752 , 753 , 754 , 755 , 756 , 757 , 758 , 759 , 760 , 761 , 762 , 763 , 764 , 765 , 766 , 767 , 768 , 769 , 770 , 771 , 772 , 773 , 774 , 775 , 776 , 777 , 778 , 779 , 780 , 781 , 782 , 783 , 784 , 785 , 786 , 787 , 788 , 789 , 790 , 791 , 792 , 793 , 794 , 795 , 796 , 797 , 798 , 799 , 800 , 801 , 802 , 803 , 804 , 805 , 806 , 807 , 808 , 809 , 810 , 811 , 812 , 813 , 814 , 815 , 816 , 817 , 818 , 819 , 820 , 821 , 822 , 823 , 824 , 825 , 826 , 827 , 828 , 829 , 830 , 831 , 832 , 833 , 834 , 835 , 836 , 837 , 838 , 839 , 840 , 841 , 842 , 843 , 844 , 845 , 846 , 847 , 848 , 849 , 850 , 851 , 852 , 853 , 854 , 855 , 856 , 857 , 858 , 859 , 860 , 861 , 862 , 863 , 864 , 865 , 866 , 867 , 868 , 869 , 870 , 871 , 872 , 873 , 874 , 875 , 876 , 877 , 878 , 879 , 880 , 881 , 882 , 883 , 884 , 885 , 886 , 887 , 888 , 889 , 890 , 891 , 892 , 893 , 894 , 895 , 896 , 897 , 898 , 899 , 900 , 901 , 902 , 903 , 904 , 905 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 916 , 917 , 918 , 919 , 920 , 921 , 922 , 923 , 924 , 925 , 926 , 927 , 928 , 929 , 930 , 931 , 932 , 933 , 934 , 935 , 936 , 937 , 938 , 939 , 940 , 941 , 942 , 943 , 944 , 945 , 946 , 947 , 948 , 949 , 950 , 951 , 952 , 953 , 954 , 955 , 956 , 957 , 958 , 959 , 960 , 961 , 962 , 963 , 964 , 965 , 966 , 967 , 968 , 969 , 970 , 971 , 972 , 973 , 974 , 975 , 976 , 977 , 978 , 979 , 980 , 981 , 982 , 983 , 984 , 985 , 986 , 987 , 988 , 989 , 990 , 991 , 992 , 993 , 994 , 995 , 996 , 997 , 998 , 999 , 1000 , 1001 , 1002 , 1003 , 1004 , 1005 , 1006 , 1007 , 1008 , 1009 , 1010 , 1011 , 1012 , 1013 , 1014 , 1015 , 1016 , 1017 , 1018 , 1019 , 1020 , 1021 , 1022 , 1023 , 1024 , 1025 , 1026 , 1027 , 1028 , 1029 , 1030 , 1031 , 1032 , 1033 , 1034 , 1035 , 1036 , 1037 , 1038 , 1039 , 1040 , 1041 , 1042 , 1043 , 1044 , 1045 , 1046 , 1047 , 1048 , 1049 , 1050 , 1051 , 1052 , 1053 , 1054 , 1055 , 1056 , 1057 , 1058 , 1059 , 1060 , 1061 , 1062 , 1063 , 1064 , 1065 , 1066 , 1067 , 1068 , 1069 , 1070 , 1071 , 1072 , 1073 , 1074 , 1075 , 1076 , 1077 , 1078 , 1079 , 1080 , 1081 , 1082 , 1083 , 1084 , 1085 , 1086 , 1087 , 1088 , 1089 , 1090 , 1091 , 1092 , 1093 , 1094 , 1095 , 1096 , 1097 , 1098 , 1099 , 1100 , 1101 , 1102 , 1103 , 1104 , 1105 , 1106 , 1107 , 1108 , 1109 , 1110 , 1111 , 1112 , 1113 , 1114 , 1115 , 1116 , 1117 , 1118 , 1119 , 1120 , 1121 , 1122 , 1123 , 1124 , 1125 , 1126 , 1127 , 1128 , 1129 , 1130 , 1131 , 1132 , 1133 , 1134 , 1135 , 1136 , 1137 , 1138 , 1139 , 1140 , 1141 , 1142 , 1143 , 1144 , 1145 , 1146 , 1147 , 1148 , 1149 , 1150 , 1151 , 1152 , 1153 , 1154 , 1155 , 1156 , 1157 , 1158 , 1159 , 1160 , 1161 , 1162 , 1163 , 1164 , 1165 , 1166 , 1167 , 1168 , 1169 , 1170 , 1171 , 1172 , 1173 , 1174 , 1175 , 1176 , 1177 , 1178 , 1179 , 1180 , 1181 , 1182 , 1183 , 1184 , 1185 , 1186 , 1187 , 1188 , 1189 , 1190 , 1191 , 1192 , 1193 , 1194 , 1195 , 1196 , 1197 , 1198 , 1199 , 1200 , 1201 , 1202 , 1203 , 1204 , 1205 , 1206 , 1207 , 1208 , 1209 , 1210 , 1211 , 1212 , 1213 , 1214 , 1215 , 1216 , 1217 , 1218 , 1219 , 1220 , 1221 , 1222 , 1223 , 1224 , 1225 , 1226 , 1227 , 1228 , 1229 , 1230 , 1231 , 1232 , 1234 , 1235 , 1236 , 1237 , 1238 , 1239 , 1240 , 1241 , 1242 , 1243 , 1244 , 1245 , 1246 , 1247 , 1248 , 1249 , 1250 , 1251 , 1252 , 1253 , 1254 , 1255 , 1256 , 1257 , 1258 , 1259 , 1260 , 1261 , 1262 , 1263 , 1264 , 1265 , 1266 , 1267 , 1268 , 1269 , 1270 , 1271 , 1272 , 1273 , 1274 , 1275 , 1276 , 1277 , 1278 , 1280 , 1281 , 1282 , 1283 , 1284 , 1285 , 1286 , 1287 , 1288 , 1289 , 1290 , 1291 , 1292 , 1293 , 1294 , 1295 , 1296 , 1297 , 1298 , 1299 , 1300 , 1301 , 1302 , 1303 , 1304 , 1305 , 1306 , 1307 , 1308 , 1309 , 1310 , 1311 , 1312 , 1313 , 1314 , 1315 , 1316 , 1317 , 1318 , 1319 , 1320 , 1321 , 1322 , 1323 , 1324 , 1325 , 1326 , 1327 , 1328 , 1329 , 1330 , 1331 , 1332 , 1333 , 1334 , 1335 , 1336 , 1337 , 1338 , 1339 , 1340 , 1341 , 1342 , 1343 , 1344 , 1345 , 1346 , 1347 , 1348 , 1349 , 1350 , 1351 , 1352 , 1353 , 1354 , 1355 , 1356 , 1357 , 1358 , 1359 , 1360 , 1361 , 1362 , 1363 , 1364 , 1365 , 1366 , 1367 , 1368 , 1369 , 1370 , 1371 , 1372 , 1373 , 1374 , 1375 , 1376 , 1377 , 1378 , 1379 , 1381 , 1382 , 1383 , 1384 , 1385 , 1386 , 1387 , 1388 , 1389 , 1390 , 1391 , 1392 , 1393 , 1394 , 1395 , 1396 , 1397 , 1398 , 1399 , 1400 , 1401 , 1402 , 1403 , 1404 , 1405 , 1406 , 1407 , 1408 , 1409 , 1410 , 1411 , 1412 , 1413 , 1414 , 1415 , 1416 , 1417 , 1418 , 1419 , 1420 , 1421 , 1422 , 1423 , 1424 , 1425 , 1426 , 1427 , 1428 , 1429 , 1430 , 1431 , 1432 , 1433 , 1434 , 1435 , 1436 , 1437 , 1438 , 1439 , 1440 , 1441 , 1442 , 1443 , 1444 , 1445 , 1446 , 1447 , 1448 , 1449 , 1450 , 1451 , 1452 , 1454 , 1455 , 1458 ) , mutation of modification site ( 1 , 29 , 1456 , 1457 ) , peptide sequencing ( 1457 ) , phospho-antibody ( 1 , 1279 , 1451 ) , phosphopeptide mapping ( 1457 ) , western blotting ( 1 , 29 , 1279 , 1451 )
Disease tissue studied:
adenoid cystic carcinoma ( 962 , 964 ) , bile-duct cancer ( 104 , 105 , 917 , 920 , 921 , 955 , 1012 , 1014 ) , bladder cancer ( 626 , 627 , 628 , 629 ) , bladder cancer, surrounding tissue ( 625 ) , bone cancer ( 29 , 46 , 1234 , 1235 , 1272 , 1273 , 1274 , 1275 , 1276 ) , Ewing's sarcoma ( 46 , 1274 ) , osteosarcoma ( 46 , 1234 , 1235 , 1272 , 1275 , 1276 ) , brain cancer ( 9 , 46 , 213 , 214 , 223 , 263 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 948 , 1023 , 1024 , 1035 , 1036 , 1037 , 1038 , 1194 , 1195 , 1196 , 1217 , 1310 , 1311 , 1312 ) , astrocytoma ( 213 , 214 , 223 , 948 ) , glioblastoma ( 9 , 263 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 ) , glioblastoma multiforme ( 1023 , 1024 , 1035 , 1036 , 1037 , 1038 , 1194 , 1195 , 1196 , 1217 , 1310 , 1311 , 1312 ) , glioma ( 9 , 263 , 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 , 1023 , 1024 , 1035 , 1036 , 1037 , 1038 , 1194 , 1195 , 1196 , 1217 , 1310 , 1311 , 1312 ) , Schwannoma ( 46 ) , breast cancer ( 4 , 14 , 24 , 38 , 44 , 260 , 264 , 323 , 327 , 328 , 385 , 395 , 619 , 620 , 621 , 622 , 623 , 624 , 708 , 709 , 1124 , 1125 , 1126 , 1127 , 1128 , 1129 , 1130 , 1131 , 1132 , 1133 , 1140 , 1141 , 1142 , 1143 , 1144 , 1146 , 1147 , 1148 , 1158 , 1214 , 1215 , 1216 , 1291 , 1327 ) , HER2 positive breast cancer ( 3 ) , luminal A breast cancer ( 3 ) , luminal B breast cancer ( 3 ) , breast cancer, surrounding tissue ( 323 , 385 , 395 , 621 , 623 , 624 ) , breast cancer, triple negative ( 3 ) , cervical cancer ( 512 ) , cervical adenocarcinoma ( 512 ) , colorectal cancer ( 29 , 46 , 116 , 117 , 118 , 205 , 210 , 219 , 220 , 282 , 283 , 287 , 288 , 290 , 322 , 396 , 397 , 398 , 399 , 400 , 401 , 402 , 404 , 834 , 867 , 868 , 869 , 870 , 876 , 878 , 994 , 1086 , 1087 , 1088 , 1089 , 1091 , 1092 , 1093 , 1094 , 1099 , 1101 , 1107 , 1108 , 1224 , 1226 , 1228 , 1229 , 1230 , 1231 , 1232 , 1282 , 1284 , 1285 , 1289 , 1290 , 1296 , 1345 , 1363 , 1364 , 1420 , 1421 ) , colorectal carcinoma ( 29 , 46 , 116 , 117 , 118 , 210 , 219 , 220 , 396 , 398 , 399 , 401 , 404 , 1228 , 1229 , 1230 , 1231 , 1232 , 1289 , 1290 , 1296 , 1345 , 1363 , 1364 , 1420 , 1421 ) , colorectal cancer, surrounding tissue ( 285 , 286 , 871 , 872 , 1098 , 1100 , 1106 ) , esophageal cancer ( 99 , 100 , 101 , 403 , 415 , 416 , 417 , 418 , 419 , 420 , 421 , 422 , 423 , 424 , 425 , 694 , 695 , 696 , 697 , 702 , 715 , 717 , 718 , 720 , 721 , 723 , 726 , 727 , 731 , 732 , 736 , 737 , 740 , 741 , 742 , 743 , 747 , 748 , 749 , 751 , 755 , 756 , 758 , 759 , 760 , 761 , 762 , 766 , 768 , 770 , 771 , 772 , 774 , 776 , 777 , 778 , 779 , 780 , 783 , 784 , 785 , 788 , 790 , 791 , 792 , 794 , 795 , 796 , 802 , 803 , 804 , 805 , 806 , 808 , 809 , 812 , 813 ) , esophageal carcinoma ( 403 , 415 , 416 , 417 , 418 , 419 , 420 , 421 , 423 , 424 ) , esophageal cancer, surrounding tissue ( 714 , 716 , 719 , 722 , 724 , 725 , 728 , 729 , 730 , 733 , 734 , 735 , 738 , 739 , 744 , 745 , 746 , 750 , 752 , 753 , 754 , 757 , 763 , 764 , 765 , 767 , 769 , 773 , 775 , 781 , 782 , 786 , 787 , 789 , 793 , 797 , 798 , 799 , 800 , 801 , 807 , 810 , 811 , 814 , 815 ) , liposarcoma ( 46 ) , gallbladder cancer ( 1018 ) , gallbladder carcinoma ( 1018 ) , gastric cancer ( 40 , 53 , 55 , 56 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 77 , 78 , 79 , 80 , 86 , 87 , 115 , 154 , 155 , 156 , 157 , 163 , 164 , 165 , 166 , 167 , 192 , 196 , 197 , 198 , 199 , 200 , 201 , 211 , 212 , 221 , 222 , 315 , 316 , 378 , 379 , 380 , 381 , 387 , 388 , 477 , 478 , 486 , 488 , 581 , 583 , 585 , 586 , 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 605 , 608 , 610 , 611 , 821 , 822 , 823 , 824 , 828 , 829 , 830 , 831 , 973 , 975 , 976 , 977 , 978 , 980 , 982 , 984 , 988 , 990 , 991 , 993 , 996 , 997 , 999 , 1000 , 1002 , 1004 , 1005 , 1006 , 1152 , 1153 , 1154 , 1165 , 1167 , 1169 , 1170 , 1171 , 1172 , 1179 , 1182 , 1187 , 1188 , 1189 , 1190 , 1191 , 1192 , 1193 , 1199 , 1200 , 1202 , 1207 , 1208 , 1209 , 1210 , 1211 , 1218 , 1349 , 1350 , 1361 , 1362 ) , gastric carcinoma ( 53 , 55 , 56 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 77 , 86 , 87 , 115 , 154 , 155 , 156 , 157 , 163 , 164 , 165 , 166 , 167 , 192 , 196 , 197 , 198 , 199 , 200 , 201 , 211 , 212 , 221 , 222 , 315 , 316 , 378 , 379 , 380 , 381 , 387 , 388 , 486 , 488 , 581 , 583 , 585 , 586 , 821 , 822 , 823 , 824 , 828 , 829 , 830 , 831 , 973 , 975 , 976 , 977 , 978 , 980 , 982 , 984 , 988 , 990 , 991 , 993 , 1152 , 1153 , 1154 , 1170 , 1171 , 1172 , 1179 , 1182 , 1192 , 1218 , 1349 , 1350 , 1361 , 1362 ) , gastric carcinoma, surrounding tissue ( 606 , 607 , 609 , 974 , 979 , 981 , 983 , 985 , 986 , 987 , 989 , 992 , 998 , 1001 , 1003 , 1007 , 1151 , 1164 , 1166 , 1168 , 1178 , 1180 , 1181 , 1201 , 1203 ) , kidney cancer ( 643 , 644 , 1240 , 1245 ) , laryngeal cancer ( 1118 , 1119 , 1120 , 1121 , 1122 , 1252 , 1253 , 1254 , 1286 , 1287 , 1288 , 1300 , 1301 , 1306 ) , leukemia ( 88 , 120 , 121 , 122 , 123 , 124 , 125 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 357 , 359 , 360 , 361 , 362 , 386 , 389 , 433 , 435 , 437 , 440 , 443 , 448 , 452 , 454 , 455 , 457 , 464 , 466 , 487 , 491 , 515 , 516 , 523 , 524 , 525 , 526 , 529 , 530 , 534 , 535 , 536 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 577 , 578 , 579 , 587 , 651 , 652 , 683 , 684 , 705 , 707 , 884 , 885 , 886 , 887 , 888 , 901 , 902 , 903 , 904 , 905 , 1102 , 1103 , 1104 , 1105 , 1116 , 1117 , 1123 , 1134 , 1135 , 1136 , 1137 , 1138 , 1139 , 1149 , 1155 , 1156 , 1175 , 1197 , 1198 , 1206 , 1212 , 1261 , 1262 , 1263 , 1264 , 1266 , 1267 , 1268 , 1269 , 1270 , 1271 , 1277 , 1278 , 1281 , 1283 , 1302 , 1303 , 1304 , 1305 , 1328 , 1329 , 1330 , 1331 , 1332 , 1333 , 1334 , 1335 , 1336 , 1337 , 1338 , 1339 , 1340 , 1341 , 1342 , 1343 , 1344 , 1351 , 1352 , 1353 , 1354 , 1355 , 1356 , 1357 , 1358 , 1359 , 1365 , 1366 , 1367 , 1368 , 1369 , 1370 ) , acute lymphocytic leukemia ( 281 ) , acute myelogenous leukemia ( 88 , 281 , 651 , 652 , 1302 , 1303 , 1304 , 1305 , 1333 , 1334 , 1335 , 1336 , 1337 , 1338 , 1339 , 1340 , 1341 , 1342 , 1343 , 1344 , 1351 , 1352 , 1353 , 1354 , 1359 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 37 ) , acute megakaryoblastic leukemia (M7) ( 37 ) , acute monoblastic leukemia (M5a) or acute monocytic leukemia (M5b) ( 37 ) , acute myeloblastic leukemia, with granulocytic maturation (M2) ( 37 ) , acute myeloblastic leukemia, without maturation (M1) ( 37 ) , chronic lymphocytic leukemia ( 357 ) , chronic myelogenous leukemia ( 120 , 121 , 122 , 123 , 124 , 125 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 359 , 360 , 361 , 362 , 386 , 389 , 433 , 435 , 437 , 440 , 443 , 448 , 452 , 454 , 455 , 457 , 464 , 466 , 487 , 491 , 515 , 516 , 523 , 524 , 525 , 526 , 529 , 530 , 534 , 535 , 536 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 577 , 578 , 579 , 587 , 683 , 684 , 705 , 707 , 884 , 885 , 886 , 887 , 888 , 901 , 902 , 903 , 904 , 905 , 1102 , 1103 , 1104 , 1105 , 1116 , 1117 , 1123 , 1134 , 1135 , 1136 , 1137 , 1138 , 1139 , 1149 , 1155 , 1156 , 1175 , 1197 , 1198 , 1206 , 1212 , 1266 , 1267 , 1268 , 1269 , 1270 , 1271 , 1277 , 1278 , 1281 , 1283 , 1328 , 1329 , 1330 , 1331 , 1332 , 1355 , 1356 , 1357 , 1358 , 1365 , 1366 , 1367 , 1368 , 1369 , 1370 ) , liver cancer ( 1 , 276 , 411 , 630 , 631 , 632 , 639 , 647 , 648 , 649 , 657 , 658 , 659 , 660 , 661 , 662 , 664 , 666 , 667 , 670 , 671 , 672 , 673 , 675 , 676 , 677 , 681 , 682 , 819 , 820 , 838 , 839 , 840 , 841 , 842 , 843 , 844 , 845 , 846 , 847 , 848 , 849 , 850 , 851 , 864 , 866 , 916 , 919 , 950 , 951 , 952 , 953 , 954 , 1017 , 1019 , 1020 , 1021 , 1022 , 1054 , 1055 , 1059 , 1067 , 1068 , 1069 , 1071 , 1073 , 1074 , 1078 , 1079 , 1080 , 1084 , 1085 , 1145 , 1150 , 1204 , 1205 ) , liver adenocarcinoma ( 820 , 1150 ) , cholangiocellular carcinoma ( 276 , 658 , 677 , 842 , 866 , 1017 , 1071 , 1078 , 1204 ) , cholangiocellular carcinoma, surrounding tissue ( 656 , 668 ) , hepatocellular carcinoma ( 647 , 648 , 657 , 659 , 660 , 661 , 662 , 664 , 666 , 667 , 670 , 671 , 672 , 673 , 676 , 681 , 682 , 838 , 843 , 844 , 848 , 850 , 851 , 864 , 1020 , 1054 , 1055 , 1067 , 1068 , 1069 , 1073 , 1074 , 1079 , 1080 , 1084 , 1085 , 1145 , 1205 ) , hepatocellular carcinoma, surrounding tissue ( 665 , 669 , 674 , 1070 , 1075 ) , liver cancer, surrounding tissue ( 1058 , 1076 ) , lung cancer ( 12 , 18 , 19 , 20 , 21 , 22 , 23 , 25 , 26 , 33 , 44 , 57 , 58 , 59 , 60 , 61 , 62 , 89 , 90 , 91 , 92 , 114 , 207 , 208 , 209 , 215 , 216 , 217 , 218 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 261 , 305 , 324 , 325 , 354 , 355 , 434 , 436 , 438 , 439 , 441 , 442 , 444 , 446 , 447 , 449 , 450 , 451 , 453 , 458 , 459 , 460 , 461 , 462 , 463 , 465 , 474 , 475 , 482 , 483 , 519 , 520 , 521 , 537 , 556 , 557 , 558 , 559 , 561 , 562 , 563 , 564 , 565 , 566 , 567 , 568 , 569 , 570 , 572 , 573 , 574 , 575 , 576 , 582 , 584 , 640 , 641 , 686 , 687 , 688 , 690 , 691 , 692 , 693 , 698 , 699 , 700 , 701 , 703 , 825 , 826 , 827 , 832 , 833 , 836 , 852 , 853 , 879 , 880 , 881 , 882 , 883 , 889 , 890 , 891 , 892 , 893 , 894 , 897 , 898 , 899 , 939 , 940 , 949 , 956 , 957 , 959 , 1008 , 1009 , 1010 , 1025 , 1095 , 1096 , 1097 , 1159 , 1160 , 1161 , 1162 , 1163 , 1173 , 1174 , 1218 , 1219 , 1221 , 1222 , 1223 , 1293 , 1294 , 1295 , 1297 , 1298 , 1320 , 1321 , 1322 , 1323 , 1324 , 1325 , 1326 , 1346 , 1347 , 1348 , 1371 , 1372 , 1373 , 1374 , 1375 , 1376 , 1377 , 1378 , 1379 , 1381 , 1382 , 1383 , 1384 , 1385 , 1386 , 1387 , 1388 , 1389 , 1390 , 1391 , 1392 , 1393 , 1394 , 1395 , 1396 , 1397 , 1398 , 1399 , 1400 , 1401 , 1402 , 1403 , 1404 , 1405 , 1406 , 1407 , 1408 , 1409 , 1410 , 1411 , 1412 , 1413 , 1414 , 1415 , 1416 , 1417 , 1418 , 1419 , 1422 , 1423 , 1424 , 1425 , 1426 , 1427 , 1428 , 1429 , 1430 , 1431 , 1432 , 1433 , 1434 , 1435 , 1436 , 1437 , 1438 , 1439 , 1440 , 1441 , 1442 , 1443 , 1444 , 1445 , 1446 , 1447 , 1448 , 1449 ) , non-small cell lung cancer ( 12 , 18 , 19 , 20 , 22 , 23 , 25 , 30 , 31 , 32 , 39 , 41 , 42 , 43 , 44 , 57 , 58 , 59 , 60 , 61 , 62 , 89 , 90 , 91 , 92 , 114 , 207 , 208 , 209 , 215 , 216 , 217 , 218 , 227 , 228 , 229 , 230 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 354 , 355 , 474 , 475 , 519 , 521 , 556 , 557 , 558 , 559 , 561 , 562 , 563 , 564 , 565 , 566 , 567 , 568 , 569 , 570 , 572 , 573 , 574 , 575 , 576 , 582 , 584 , 640 , 641 , 688 , 700 , 701 , 825 , 826 , 827 , 832 , 833 , 836 , 852 , 853 , 879 , 880 , 881 , 882 , 893 , 897 , 898 , 899 , 939 , 940 , 949 , 959 , 1008 , 1025 , 1095 , 1096 , 1097 , 1159 , 1160 , 1161 , 1162 , 1163 , 1173 , 1174 , 1218 , 1219 , 1221 , 1222 , 1223 , 1293 , 1294 , 1295 , 1297 , 1298 , 1320 , 1321 , 1322 , 1323 , 1324 , 1325 , 1326 , 1346 , 1347 , 1348 , 1371 , 1372 , 1373 , 1374 , 1375 , 1376 , 1377 , 1378 , 1379 , 1381 , 1382 , 1383 , 1384 , 1385 , 1386 , 1387 , 1388 , 1389 , 1390 , 1391 , 1392 , 1393 , 1394 , 1395 , 1396 , 1397 , 1398 , 1399 , 1400 , 1401 , 1402 , 1403 , 1404 , 1405 , 1406 , 1413 , 1414 , 1415 , 1416 , 1417 , 1418 , 1419 , 1422 , 1423 , 1424 , 1425 , 1426 , 1433 , 1434 , 1435 , 1436 , 1437 , 1438 , 1439 , 1440 , 1441 , 1444 , 1445 , 1446 , 1447 , 1448 , 1449 ) , non-small cell lung adenocarcinoma ( 12 , 18 , 19 , 20 , 21 , 22 , 23 , 25 , 26 , 31 , 32 , 33 , 89 , 90 , 91 , 92 , 114 , 209 , 217 , 218 , 227 , 228 , 229 , 230 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 354 , 355 , 556 , 557 , 558 , 559 , 561 , 562 , 563 , 564 , 565 , 566 , 567 , 568 , 569 , 570 , 572 , 573 , 574 , 575 , 576 , 582 , 584 , 688 , 825 , 826 , 827 , 832 , 879 , 880 , 881 , 882 , 949 , 959 , 1008 , 1095 , 1096 , 1097 , 1320 , 1321 , 1323 , 1324 , 1325 , 1326 , 1347 , 1348 ) , non-small cell lung adenocarcinoma, surrounding tissue ( 560 , 571 ) , non-small cell large cell lung carcinoma ( 19 , 22 ) , non-small cell squamous cell lung carcinoma ( 21 , 43 , 90 , 231 , 582 , 584 , 686 , 687 , 690 , 691 , 692 , 693 , 698 , 699 , 703 , 825 , 826 , 827 , 832 , 883 , 889 , 890 , 891 , 892 , 894 , 1009 , 1010 , 1320 , 1321 ) , lung cancer, surrounding tissue ( 262 , 326 , 445 , 456 ) , lymphoma ( 15 , 1183 , 1184 , 1185 , 1186 , 1279 ) , B cell lymphoma ( 37 ) , Burkitt's lymphoma ( 15 ) , non-Hodgkin's lymphoma ( 37 ) , follicular lymphoma ( 15 ) , mantle cell lymphoma ( 15 ) , neuroblastoma ( 8 , 36 , 307 , 308 , 310 , 311 , 312 , 313 , 314 , 349 , 350 , 931 , 932 , 933 , 934 , 935 , 1026 , 1029 , 1030 , 1031 , 1032 , 1042 , 1043 , 1176 , 1177 , 1236 , 1237 , 1238 , 1239 , 1241 , 1242 , 1243 , 1244 ) , ovarian cancer ( 102 , 103 , 265 , 291 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 299 , 300 , 301 , 302 , 303 , 304 , 329 , 330 , 331 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 339 , 348 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 476 , 479 , 480 , 481 , 484 , 493 , 494 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 510 , 511 , 1246 , 1247 , 1248 , 1249 , 1250 , 1251 , 1255 , 1256 , 1257 , 1258 , 1259 , 1260 ) , ovarian epithelial carcinoma ( 102 , 103 , 265 , 293 , 298 , 348 ) , pancreatic cancer ( 645 , 704 , 1292 ) , pancreatic carcinoma ( 645 , 1292 ) , pancreatic cancer, surrounding tissue ( 706 , 1157 ) , multiple myeloma ( 37 , 817 , 818 ) , salivary gland cancer ( 923 , 926 , 927 , 928 , 929 , 930 ) , melanoma skin cancer ( 7 , 538 , 539 , 540 , 541 , 542 , 543 , 544 , 545 , 546 , 873 , 874 , 875 , 877 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 918 , 941 , 942 , 943 , 944 , 945 , 1011 , 1013 , 1015 , 1016 , 1040 , 1041 , 1056 , 1057 ) , leiomyosarcoma ( 46 ) , rhabdomyosarcoma ( 46 ) , teratoma ( 473 ) , testicular cancer ( 405 ) , thymic carcinoma ( 251 , 252 , 253 , 254 ) , thyroid cancer, surrounding tissue ( 1051 ) , ventricular tachycardia ( 255 )
Relevant cell line - cell type - tissue:
'fat, white' ( 46 ) , 'liver, para-cholangiocellular carcinoma tissue' ( 276 ) , 'stem, embryonic' ( 663 ) , 143.98.2 (bone cell) ( 1276 ) , 143B (bone cell) ( 1235 ) , 184A1 (epithelial) ( 1450 ) , 23132/87 (gastric) ( 80 ) , 23132/87 (gastric) [RAIG1 (human), knockdown] ( 78 , 79 ) , 293 (epithelial) ( 279 , 367 , 368 , 369 , 816 ) , 293 (epithelial) [ADRB1 (human), no information, overexpresses human beta1-adrenergic (ß1AR- HEK293)] ( 1112 ) , 293 (epithelial) [AT1 (human), transfection, AT1R stable transfected HEK293] ( 353 ) , 293 (epithelial) [AT1 (human), transfection] ( 321 ) , 293 (epithelial) [EFNB1 (human), transfection] ( 517 ) , 293 (epithelial) [EphB2 (human), transfection] ( 517 ) , 293E (epithelial) ( 206 ) , 293T (epithelial) ( 6 , 924 , 925 , 1360 ) , 44-ZW-5409 (eye cell) ( 1312 ) , 47-CD-3188 (glial) ( 1310 ) , 56-DT-9110 (glial) ( 1311 ) , 703167 (pulmonary) ( 436 ) , 786-O (renal) [VHL (human), transfection] ( 5 ) , A204 (muscle cell) ( 46 ) , A498 (renal) ( 373 ) , A549 (pulmonary) ( 18 , 27 , 33 , 39 , 89 , 114 , 1095 ) , A549 (pulmonary) [LKB1 (human), no information] ( 1096 ) , A673 (muscle cell) ( 46 ) , ACC-S (adenoidal) ( 961 , 963 ) , AML-193 (monocyte) ( 37 ) , AZ-521 (gastric) ( 1189 ) , BEAS-2B (epithelial) ( 854 , 855 ) , BEAS-2B (epithelial) [LKB1 (human), no information] ( 856 , 857 ) , BJAB (B lymphocyte) ( 15 ) , bladder ( 625 , 626 , 627 , 628 , 629 ) , bone marrow ( 281 , 651 , 652 , 1302 , 1303 , 1304 , 1305 , 1333 , 1334 , 1335 , 1336 , 1337 , 1338 , 1343 , 1344 , 1351 , 1352 , 1353 , 1354 , 1359 ) , breast ( 3 , 260 , 264 , 323 , 327 , 328 , 385 , 395 , 619 , 620 , 621 , 622 , 623 , 624 , 1124 , 1125 , 1126 , 1127 , 1128 , 1129 , 1130 , 1131 , 1132 , 1133 , 1140 , 1141 , 1142 , 1143 , 1144 , 1146 , 1147 , 1148 , 1158 , 1214 , 1215 , 1216 , 1291 ) , BT-20 (breast cell) ( 44 ) , BT-474 (breast cell) ( 4 , 708 ) , BT-549 (breast cell) ( 44 ) , Cal-12T (pulmonary) ( 25 ) , Calu 6 (pulmonary) ( 44 ) , Calu-3 (pulmonary) ( 20 ) , cholangiocyte-liver ( 658 , 677 , 842 , 866 , 1071 , 1078 , 1204 ) , CL1-0 (pulmonary) ( 305 ) , CL1-1 (pulmonary) ( 305 ) , CL1-2 (pulmonary) ( 305 ) , CL1-5 (pulmonary) ( 305 ) , CMK (megakaryoblast) ( 37 ) , COLO-680N (esophageal) ( 101 , 425 ) , COLO-680N (esophageal) [RAIG1 (human), knockdown] ( 99 , 100 ) , colon ( 282 , 283 , 285 , 286 , 287 , 288 , 290 , 322 , 396 , 397 , 398 , 399 , 400 , 401 , 402 , 404 , 834 , 867 , 868 , 869 , 870 , 871 , 872 , 876 , 878 , 994 , 1086 , 1087 , 1088 , 1089 , 1091 , 1092 , 1093 , 1094 , 1098 , 1099 , 1100 , 1101 , 1106 , 1107 , 1108 , 1224 , 1226 , 1282 , 1284 , 1285 , 1289 , 1290 , 1296 , 1299 , 1410 ) , COS (fibroblast) ( 1308 , 1457 ) , CTS (myeloid) ( 37 ) , DG75 (B lymphocyte) ( 309 ) , DLD1 (intestinal) ( 46 , 205 ) , DMS153 (pulmonary) ( 23 ) , DOHH2 ('B lymphocyte, precursor') ( 37 ) , EGI-1 (bile-duct cell) ( 1012 ) , endothelial-aorta ( 45 ) , esophagus ( 403 , 694 , 695 , 696 , 697 , 702 , 714 , 715 , 716 , 717 , 718 , 719 , 720 , 721 , 722 , 723 , 724 , 725 , 726 , 727 , 728 , 729 , 730 , 731 , 732 , 733 , 734 , 735 , 736 , 737 , 738 , 739 , 740 , 741 , 742 , 743 , 744 , 745 , 746 , 747 , 748 , 749 , 750 , 751 , 752 , 753 , 754 , 755 , 756 , 757 , 758 , 759 , 760 , 761 , 762 , 763 , 764 , 765 , 766 , 767 , 768 , 769 , 770 , 771 , 772 , 773 , 774 , 775 , 776 , 777 , 778 , 779 , 780 , 781 , 782 , 783 , 784 , 785 , 786 , 787 , 788 , 789 , 790 , 791 , 792 , 793 , 794 , 795 , 796 , 797 , 798 , 799 , 800 , 801 , 802 , 803 , 804 , 805 , 806 , 807 , 808 , 809 , 810 , 811 , 812 , 813 , 814 , 815 ) , FL-18 (B lymphocyte) ( 15 ) , FL-318 (B lymphocyte) ( 15 ) , Flp-In T-Rex-293 (epithelial) ( 49 ) , Flp-In T-Rex-293 (epithelial) [PRKD1 (human), genetic knockin] ( 49 ) , FU97 (gastric) ( 477 , 478 , 1190 ) , G-292 (bone cell) ( 1272 ) , glial-brain ( 9 ) , GRANTA-519 (B lymphocyte) ( 1183 ) , H2009 (pulmonary) ( 44 ) , H2077 (pulmonary) ( 44 ) , H2887 (pulmonary) ( 44 ) , H322 (pulmonary) ( 44 ) , H322M (pulmonary) ( 44 ) , HCC1359 (pulmonary) ( 44 ) , HCC15 (pulmonary) ( 21 ) , HCC1937 (breast cell) ( 44 ) , HCC2279 (pulmonary) ( 44 ) , HCC366 (pulmonary) ( 44 ) , HCC4006 (pulmonary) ( 44 ) , HCC44 (pulmonary) ( 25 ) , HCC78 (pulmonary) ( 22 , 44 , 209 , 217 , 218 , 949 ) , HCC827 (pulmonary) ( 20 , 44 , 354 , 355 , 1347 , 1348 ) , HCT116 (intestinal) ( 29 , 116 , 117 , 118 , 210 , 219 , 220 , 680 , 1345 , 1363 , 1364 ) , heart ( 255 ) , HEL (erythroid) ( 37 ) , HeLa (cervical) ( 2 , 10 , 34 , 485 , 489 , 490 , 513 , 522 , 837 , 860 , 922 , 1053 , 1063 , 1064 , 1065 , 1066 , 1112 , 1113 , 1455 , 1456 , 1457 ) , HeLa (cervical) [OGT (rat), transfection] ( 513 ) , HeLa S3 (cervical) ( 275 , 512 , 1052 ) , HeLa_Hesp (cervical) ( 280 ) , HeLa_LOG (cervical) ( 280 ) , HeLa_Meta (cervical) ( 366 ) , HeLa_NOC (cervical) ( 280 ) , HeLa_Pro (cervical) ( 366 ) , HeLa_Telo (cervical) ( 366 ) , Hep3B (hepatic) ( 953 ) , hepatic-'liver, para-cholangiocellular carcinoma tissue' ( 656 , 668 ) , hepatic-'liver, para-hepatocellular carcinoma tissue' ( 665 , 669 , 674 , 1070 , 1075 ) , hepatocyte-liver ( 647 , 648 , 657 , 659 , 660 , 661 , 662 , 664 , 666 , 667 , 670 , 671 , 672 , 673 , 676 , 838 , 843 , 844 , 848 , 864 , 1067 , 1068 , 1069 , 1073 , 1079 , 1080 , 1084 , 1085 , 1145 , 1205 ) , HepG2 (hepatic) ( 1 , 682 ) , HES-3 ('stem, embryonic') ( 277 ) , HLE (hepatic) ( 850 ) , HLF (hepatic) ( 681 ) , HMLER ('stem, breast cancer') ( 14 ) , HMLER ('stem, breast cancer') [CXCR4 (human), knockdown] ( 14 ) , HOP62 (pulmonary) ( 44 ) , HOS (bone cell) ( 1234 ) , HPAC (pancreatic) ( 645 ) , HuCCT1 (hepatic) ( 1017 ) , HUES-9 ('stem, embryonic') ( 278 ) , Huh1 (hepatic) ( 851 ) , Huh28 (hepatic) ( 952 ) , Huh6 (hepatic) ( 1021 ) , Huh7 (hepatic) ( 1022 ) , HUVEC (endothelial) ( 965 , 966 , 967 , 968 , 969 , 970 , 971 , 972 ) , IM95 (gastric) ( 1191 ) , JEKO-1 (B lymphocyte) ( 15 , 1184 ) , JHH-1 (hepatic) ( 1019 ) , JHH-4 (hepatic) ( 916 ) , JHH-5 (hepatic) ( 954 ) , JHH-6 (hepatic) ( 951 ) , JHH-7 (hepatic) ( 950 ) , Jurkat (T lymphocyte) ( 28 , 47 , 54 , 76 , 81 , 82 , 96 , 97 , 98 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 126 , 127 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 158 , 159 , 160 , 161 , 162 , 168 , 169 , 170 , 171 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 , 187 , 188 , 189 , 190 , 191 , 193 , 194 , 195 , 202 , 203 , 204 , 224 , 225 , 226 , 246 , 247 , 248 , 249 , 250 , 256 , 257 , 258 , 259 , 284 , 289 , 317 , 318 , 319 , 320 , 340 , 341 , 342 , 343 , 344 , 345 , 346 , 347 , 363 , 364 , 365 , 370 , 371 , 372 , 374 , 375 , 376 , 377 , 382 , 383 , 384 , 390 , 391 , 392 , 406 , 407 , 408 , 409 , 410 , 412 , 413 , 414 , 467 , 468 , 469 , 470 , 471 , 492 , 514 , 518 , 527 , 528 , 531 , 532 , 580 , 612 , 613 , 614 , 615 , 616 , 617 , 618 , 633 , 634 , 635 , 636 , 637 , 638 , 642 , 646 , 650 , 653 , 654 , 655 , 679 , 685 , 689 , 710 , 711 , 712 , 713 , 835 , 861 , 862 , 863 , 895 , 896 , 900 , 936 , 937 , 938 , 946 , 947 , 958 , 960 , 995 , 1027 , 1028 , 1033 , 1034 , 1039 , 1044 , 1045 , 1046 , 1047 , 1048 , 1049 , 1050 , 1060 , 1072 , 1081 , 1082 , 1083 , 1090 , 1213 , 1220 , 1225 , 1227 , 1280 , 1307 , 1309 , 1313 , 1314 , 1315 , 1316 , 1317 , 1318 , 1319 , 1345 , 1451 , 1454 ) , Jurkat E6-1 (T lymphocyte) ( 35 ) , K4 (synoviocyte) ( 11 ) , K562 (erythroid) ( 34 , 120 , 121 , 122 , 123 , 124 , 125 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 359 , 360 , 361 , 362 , 386 , 389 , 433 , 435 , 437 , 440 , 443 , 448 , 452 , 454 , 455 , 457 , 464 , 466 , 487 , 491 , 515 , 516 , 522 , 523 , 524 , 525 , 526 , 529 , 530 , 534 , 535 , 536 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 577 , 578 , 579 , 587 , 683 , 684 , 705 , 707 , 884 , 885 , 886 , 887 , 888 , 901 , 902 , 903 , 904 , 905 , 1077 , 1102 , 1103 , 1104 , 1105 , 1116 , 1117 , 1123 , 1134 , 1135 , 1136 , 1137 , 1138 , 1139 , 1149 , 1155 , 1156 , 1175 , 1197 , 1198 , 1206 , 1212 , 1266 , 1267 , 1268 , 1269 , 1270 , 1271 , 1277 , 1278 , 1281 , 1283 , 1328 , 1329 , 1330 , 1331 , 1332 , 1355 , 1356 , 1357 , 1358 , 1365 , 1366 , 1367 , 1368 , 1369 , 1370 ) , Kasumi-1 (myeloid) ( 37 ) , KATO III (gastric) ( 581 , 586 , 821 , 822 , 823 , 824 ) , KG-1 (myeloid) ( 37 , 88 ) , kidney ( 643 , 644 , 1240 , 1245 ) , KMS-11 (B lymphocyte) ( 533 ) , KPL-4 (breast cell) ( 24 ) , KURAMOCHI (ovarian) ( 337 ) , KY821 (myeloid) ( 281 ) , Kyse140 (esophageal) ( 421 ) , Kyse150 (esophageal) ( 416 ) , Kyse180 (esophageal) ( 424 ) , Kyse270 (esophageal) ( 419 ) , Kyse30 (esophageal) ( 415 ) , Kyse410 (esophageal) ( 420 ) , Kyse450 (squamous) ( 422 ) , Kyse510 (esophageal) ( 418 ) , Kyse520 (esophageal) ( 417 ) , Kyse70 (esophageal) ( 423 ) , LAN-6 (neural crest) ( 8 , 310 , 312 , 931 , 932 , 933 , 934 , 935 , 1029 , 1030 , 1031 , 1032 ) , larynx ( 1118 , 1119 , 1120 , 1121 , 1122 , 1252 , 1253 , 1254 , 1286 , 1287 , 1288 , 1300 , 1301 , 1306 ) , LCLC-103H (pulmonary) ( 44 ) , liver ( 1 , 276 , 411 , 630 , 631 , 632 , 639 , 649 , 675 , 839 , 840 , 841 , 845 , 846 , 847 , 1054 , 1055 , 1058 , 1059 , 1074 , 1076 ) , LN18 (glial) ( 1023 , 1024 , 1035 , 1036 , 1037 , 1038 , 1194 , 1195 , 1196 , 1217 ) , LN428_LNZ308 (glial) [EGFR (human), transfection, EGFR (wildtype)] ( 263 ) , LN428_LNZ308 (glial) [EGFR (human), transfection, EGFRvIII mutant (aka Delta EGFR, d2-7 EGFR; del. exon 2-7; in-frame loss 801 bp/267 aa in EC domain)] ( 263 ) , LN428_LNZ308 (glial) [EGFR (human), transfection, EGFRvIII-ki mutant (deletion of exons 2-7 plus kinase inactive mutation)] ( 263 ) , LN444 (glial) ( 588 , 589 , 590 , 591 , 592 , 593 , 594 , 595 , 596 ) , LOU-NH91 (squamous) ( 21 , 44 ) , lung ( 12 , 18 , 19 , 20 , 21 , 22 , 23 , 25 , 26 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 261 , 262 , 324 , 325 , 326 , 434 , 438 , 439 , 441 , 442 , 444 , 445 , 446 , 447 , 449 , 450 , 451 , 453 , 456 , 458 , 459 , 460 , 461 , 462 , 463 , 465 , 474 , 475 , 519 , 520 , 521 , 537 , 556 , 557 , 558 , 559 , 560 , 561 , 562 , 563 , 564 , 565 , 566 , 567 , 568 , 569 , 570 , 571 , 572 , 573 , 574 , 575 , 576 , 640 , 641 , 686 , 687 , 688 , 690 , 691 , 692 , 693 , 698 , 699 , 700 , 701 , 703 , 833 , 836 , 879 , 880 , 881 , 882 , 883 , 889 , 890 , 891 , 892 , 894 , 956 , 957 , 959 , 1008 , 1009 , 1010 , 1025 , 1159 , 1160 , 1161 , 1162 , 1163 , 1173 , 1174 , 1219 , 1221 , 1222 , 1223 , 1293 , 1294 , 1295 , 1297 , 1298 , 1371 , 1372 , 1373 , 1374 , 1375 , 1376 , 1377 , 1378 , 1379 , 1381 , 1382 , 1383 , 1384 , 1385 , 1386 , 1387 , 1388 , 1389 , 1390 , 1391 , 1392 , 1393 , 1394 , 1395 , 1396 , 1397 , 1398 , 1399 , 1400 , 1401 , 1402 , 1403 , 1404 , 1405 , 1406 , 1407 , 1408 , 1409 , 1411 , 1412 , 1413 , 1414 , 1415 , 1416 , 1417 , 1418 , 1419 , 1422 , 1423 , 1424 , 1425 , 1426 , 1427 , 1428 , 1429 , 1430 , 1431 , 1432 , 1433 , 1434 , 1435 , 1436 , 1437 , 1438 , 1439 , 1440 , 1441 , 1442 , 1443 , 1444 , 1445 , 1446 , 1447 , 1448 , 1449 ) , M059K (glial) ( 1452 ) , Marimo (myeloid) ( 281 ) , MAVER-1 (B lymphocyte) ( 1185 ) , MCAS (ovarian) ( 304 ) , MCF-10A (breast cell) ( 306 ) , MCF-10A (breast cell) [CSFR (human), transfection] ( 306 ) , MCF-7 (breast cell) ( 4 , 44 ) , MDA-MB-231 (breast cell) ( 44 ) , MDA-MB-361 (breast cell) ( 709 ) , MDA-MB-435S (breast cell) ( 680 ) , MDA-MB-468 (breast cell) ( 44 ) , ME-F2 (myeloid) ( 281 ) , MG63 (bone cell) ( 46 ) , MKN-1 (gastric) ( 1192 ) , MKN-45 (gastric) ( 40 , 48 , 53 , 55 , 56 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 77 , 86 , 87 , 115 , 154 , 155 , 156 , 157 , 163 , 164 , 165 , 166 , 167 , 192 , 196 , 197 , 198 , 199 , 200 , 201 , 211 , 212 , 221 , 222 , 315 , 316 , 378 , 379 , 380 , 381 , 387 , 388 , 486 , 488 , 583 , 585 , 828 , 829 , 830 , 831 , 1218 , 1349 , 1350 , 1361 , 1362 ) , MKN-7 (gastric) ( 1209 ) , MKN-74 (gastric) ( 1210 ) , ML-1 (myeloid) ( 281 ) , MNNG-HOS (bone cell) ( 46 ) , Molm 14 (myeloid) ( 281 ) , muscle ( 46 ) , MV4-11 (macrophage) ( 37 , 281 , 680 , 1341 , 1342 ) , NB10 (neural crest) ( 36 ) , NCCIT (epithelial) ( 473 ) , NCEB-1 (B lymphocyte) ( 15 ) , NCI-H1299 (pulmonary) ( 19 ) , NCI-H1355 (pulmonary) ( 18 ) , NCI-H1395 (pulmonary) ( 44 ) , NCI-H1437 (pulmonary) ( 23 , 25 ) , NCI-H1568 (pulmonary) ( 44 ) , NCI-H157 (pulmonary) ( 44 ) , NCI-H1648 (pulmonary) ( 44 ) , NCI-H1650 (pulmonary) ( 20 , 57 , 58 , 59 , 60 , 61 , 62 , 207 , 208 , 215 , 216 , 893 , 897 , 898 , 899 ) , NCI-H1666 (pulmonary) ( 25 , 44 ) , NCI-H1703 (squamous) ( 21 , 43 , 48 , 90 , 582 , 584 , 825 , 826 , 827 , 832 , 1320 , 1321 ) , NCI-H1734 (pulmonary) ( 19 ) , NCI-H1781 (pulmonary) ( 22 ) , NCI-H1792 (pulmonary) ( 18 , 858 , 859 ) , NCI-H1792 (pulmonary) [LKB1 (human), no information] ( 852 , 853 ) , NCI-H1944 (pulmonary) ( 19 ) , NCI-H1975 (pulmonary) ( 20 ) , NCI-H2030 (pulmonary) ( 44 ) , NCI-H2073 (pulmonary) ( 21 , 23 ) , NCI-H209 (pulmonary) ( 23 ) , NCI-H2106 (pulmonary) ( 20 ) , NCI-H2126 (pulmonary) ( 1097 ) , NCI-H2172 (pulmonary) ( 44 ) , NCI-H2228 (pulmonary) ( 22 , 31 , 32 ) , NCI-H23 (pulmonary) ( 18 ) , NCI-H2342 (pulmonary) ( 21 ) , NCI-H2405 (pulmonary) ( 25 ) , NCI-H3122 (pulmonary) ( 22 , 30 , 91 ) , NCI-H3255 (pulmonary) ( 41 , 42 , 48 , 92 , 1218 , 1346 ) , NCI-H358 (pulmonary) ( 19 , 939 ) , NCI-H358 (pulmonary) [LKB1 (human), no information] ( 940 ) , NCI-H441 (pulmonary) ( 18 ) , NCI-H460 (pulmonary) ( 19 , 44 , 837 ) , NCI-H520 (squamous) ( 44 ) , NCI-H647 (pulmonary) ( 44 ) , NCI-H661 (pulmonary) ( 22 ) , NCI-H838 (pulmonary) ( 23 ) , NCI-H929 (B lymphocyte) ( 817 ) , nerve ( 46 ) , NOMO-1 (myeloid) ( 281 , 1339 , 1340 ) , NPC (neural crest) ( 36 ) , NT2 (testicular) ( 472 ) , NUGC-2 (gastric) ( 1207 ) , NUGC-3 (gastric) ( 1193 ) , NUGC-4 (gastric) ( 1208 ) , OCI-ly1 (B lymphocyte) ( 15 ) , OCI/AML3 (myeloid) ( 281 ) , OCUG-1 ( 1018 ) , OCUM-1 (gastric) ( 1187 ) , OPM-2 (plasma cell) ( 37 ) , ovary ( 329 , 330 , 331 , 348 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 476 , 479 , 480 , 481 , 484 , 493 , 494 , 495 , 496 , 497 , 498 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 507 , 508 , 509 , 510 , 511 , 1246 , 1247 , 1248 , 1249 , 1250 , 1251 , 1255 , 1256 , 1257 , 1258 , 1259 , 1260 ) , OVCAR8 (ovarian) ( 301 , 339 ) , OVISE (ovarian) ( 303 ) , OVKATE (ovarian) ( 291 , 294 , 302 , 335 ) , OVMANA (ovarian) ( 265 , 293 , 298 ) , OVMANA (ovarian) [RAIG1 (human), knockdown] ( 102 , 103 ) , OVMIU (ovarian) ( 296 , 332 ) , OVSAHO (ovarian) ( 295 , 334 ) , OZ (bile-duct cell) ( 105 , 955 ) , OZ (bile-duct cell) [RAIG1 (human), knockdown] ( 104 ) , P116 (T lymphocyte) [ZAP70 (human), homozygous knockout] ( 555 ) , P31/FUJ (erythroid) ( 37 ) , pancreas ( 704 , 706 , 1157 , 1292 ) , PC9 (pulmonary) ( 44 , 1322 , 1323 , 1324 , 1325 , 1326 ) , PLC/PRF/5 (hepatic) ( 849 ) , Raji (B lymphocyte) ( 15 ) , RAMOS (B lymphocyte) ( 15 ) , RD-ES (bone cell) ( 46 ) , RD18 (muscle cell) ( 46 ) , REC-1 (B lymphocyte) ( 15 , 1186 ) , RERF-GC-1B (gastric) ( 1188 ) , RL ('B lymphocyte, precursor') ( 37 ) , RMG1 (ovarian) ( 300 , 336 ) , RMUG-S (ovarian) ( 292 , 299 , 338 ) , RPMI-8226 (plasma cell) ( 37 ) , RS4;11 (B lymphocyte) ( 281 ) , SACC-83 (salivary gland) ( 962 , 964 ) , salivary gland ( 923 , 926 , 927 , 928 , 929 , 930 ) , Saos-2 (bone cell) ( 46 , 1273 ) , SCH (gastric) ( 1211 ) , SEM (B lymphocyte) ( 281 ) , SH-SY5Y (neural crest) ( 8 , 307 , 308 , 349 , 350 ) , SH-SY5Y (neural crest) [LRRK2 (human), transfection, over-expression of LRRK2(G2019S)] ( 16 ) , SK-ES-1 ( 1274 ) , SK-HEP-1 (endothelial) ( 820 , 1150 ) , SK-LMS-1 (muscle cell) ( 46 ) , SKBr3 (breast cell) ( 38 ) , skin ( 393 , 394 , 538 , 539 , 540 , 541 , 542 , 543 , 544 , 545 , 546 , 873 , 874 , 875 , 877 , 906 , 907 , 908 , 909 , 910 , 911 , 912 , 913 , 914 , 915 , 918 , 941 , 942 , 943 , 944 , 945 , 1011 , 1013 , 1015 , 1016 , 1040 , 1041 , 1056 , 1057 ) , SKNBE(2) (neural crest) ( 8 , 313 , 314 , 1176 , 1177 ) , SMS-KCN (neural crest) ( 8 , 1026 , 1042 , 1043 , 1236 , 1237 , 1238 , 1239 , 1241 , 1242 , 1243 , 1244 ) , SMS-KCN-A (neural crest) ( 8 , 311 ) , SNU-1196 (hepatic) ( 917 ) , SNU-182 (hepatic) ( 1020 ) , SNU-308 (bile-duct cell) ( 920 ) , SNU-398 (hepatic) ( 919 ) , SNU-449 (hepatic) ( 819 ) , SNU-478 (bile-duct cell) ( 921 ) , stomach ( 597 , 598 , 599 , 600 , 601 , 602 , 603 , 604 , 605 , 606 , 607 , 608 , 609 , 610 , 611 , 973 , 974 , 975 , 976 , 977 , 978 , 979 , 980 , 981 , 982 , 983 , 984 , 985 , 986 , 987 , 988 , 989 , 990 , 991 , 992 , 993 , 996 , 997 , 998 , 999 , 1000 , 1001 , 1002 , 1003 , 1004 , 1005 , 1006 , 1007 , 1151 , 1152 , 1153 , 1154 , 1164 , 1165 , 1166 , 1167 , 1168 , 1169 , 1170 , 1171 , 1172 , 1178 , 1179 , 1180 , 1181 , 1182 , 1199 , 1200 , 1201 , 1202 , 1203 ) , SU-DHL-4 (B lymphocyte) ( 15 ) , SU-DHL-6 (B lymphocyte) ( 37 ) , SW480 (intestinal) ( 1228 , 1229 , 1230 , 1231 , 1232 , 1420 ) , SW620 (intestinal) ( 1421 ) , T1-73 (bone cell) ( 1275 ) , testis ( 405 ) , TFK-1 (bile-duct cell) ( 1014 ) , thymus ( 251 , 252 , 253 , 254 ) , thyroid ( 1051 ) , TYK-nu (ovarian) ( 297 , 333 ) , U-118MG (glial) ( 213 , 214 , 223 , 948 ) , U-937 (myeloid) ( 1279 ) , U266 (plasma cell) ( 37 , 818 ) , U2OS (bone cell) ( 29 , 46 ) , UACC-893 (breast cell) ( 1327 ) , UPN-1 (B lymphocyte) ( 15 ) , WM115 (melanocyte) ( 865 ) , WM239A (epidermal) ( 7 )

Upstream Regulation
Regulatory protein:
CSFR (human) ( 306 ) , MCM3 (human) ( 145 )
Putative in vivo kinases:
Wee1 (human) ( 1380 )
Phosphatases, in vitro:
CDC25A (human) ( 1457 )
Treatments:
adriamycin ( 1456 ) , aphidicolin ( 1451 ) , arsenite ( 1279 ) , CXCL12 ( 14 ) , ephrin_B2 ( 517 ) , high_glucose ( 1 ) , HU-210 ( 1456 ) , imatinib ( 48 ) , lapatinib ( 38 ) , low_glucose ( 1 ) , metastatic potential ( 305 ) , MG132 ( 366 ) , nocodazole ( 512 , 1451 ) , quinalizarin ( 6 )

Downstream Regulation
Effects of modification on CDK2:
enzymatic activity, inhibited ( 1453 , 1456 , 1457 ) , protein conformation ( 1453 ) , protein stabilization ( 29 )
Effects of modification on biological processes:
cell cycle regulation ( 29 , 1457 )

References 

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Franchin C, et al. (2015) Quantitative analysis of a phosphoproteome readily altered by the protein kinase CK2 inhibitor quinalizarin in HEK-293T cells. Biochim Biophys Acta 1854, 609-23
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Palacios-Moreno J, et al. (2015) Neuroblastoma Tyrosine Kinase Signaling Networks Involve FYN and LYN in Endosomes and Lipid Rafts. PLoS Comput Biol 11, e1004130
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Yoshida T, et al. (2014) Tyrosine phosphoproteomics identifies both codrivers and cotargeting strategies for T790M-related EGFR-TKI resistance in non-small cell lung cancer. Clin Cancer Res 20, 4059-74
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Rikova K, Hall B (2013) CST Curation Set: 20736, 21163, 30158, 30159, 30160; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

19

Rikova K, Hall B (2013) CST Curation Set: 20737, 21164, 30161, 30162, 30163; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

20

Rikova K, Hall B (2013) CST Curation Set: 20738, 21165, 30164, 30165, 30166; Year: 2013; Biosample/Treatment: cell line, H1650, HCC827, H1975, Calu-3, H2106; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

21

Rikova K, Hall B (2013) CST Curation Set: 20739, 21166, 30167, 30168, 30169; Year: 2013; Biosample/Treatment: cell line, H2342, H2073, Lou-NH91, HCC15, H1703; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

22

Rikova K, Hall B (2013) CST Curation Set: 20740, 21167, 30170, 30171, 30172; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

23

Rikova K, Hall B (2013) CST Curation Set: 20742, 21169, 30176, 30177, 30178; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
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24

Tzouros M, et al. (2013) Development of a 5-plex SILAC method tuned for the quantitation of tyrosine phosphorylation dynamics. Mol Cell Proteomics 12, 3339-49
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Rikova K, Hall B (2013) CST Curation Set: 20741, 21168, 30173, 30174, 30175; Year: 2013; Biosample/Treatment: cell line, H1666, CAL-12T, H2405, HCC44, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

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Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
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Kim JY, et al. (2013) Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proc Natl Acad Sci U S A 110, 12414-9
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Hughes BT, et al. (2013) Essential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation. Proc Natl Acad Sci U S A 110, 8954-9
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Rikova K (2013) CST Curation Set: 18459; Year: 2013; Biosample/Treatment: cell line, H3122/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](AGC)
Curated Info

31

Rikova K (2013) CST Curation Set: 18458; Year: 2013; Biosample/Treatment: cell line, H2228/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](AGC)
Curated Info

32

Rikova K (2013) CST Curation Set: 18449; Year: 2012; Biosample/Treatment: cell line, H2228/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
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33

Johnson H, Lescarbeau RS, Gutierrez JA, White FM (2013) Phosphotyrosine profiling of NSCLC cells in response to EGF and HGF reveals network specific mediators of invasion. J Proteome Res 12, 1856-67
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Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
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Helou YA, Nguyen V, Beik SP, Salomon AR (2013) ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. PLoS One 8, e69641
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DeNardo BD, et al. (2013) Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. PLoS One 8, e82513
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37

Casado P, et al. (2013) Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors. Genome Biol 14, R37
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38

Imami K, et al. (2012) Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways. Mol Cell Proteomics 11, 1741-57
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39

Rikova K (2012) CST Curation Set: 16140; Year: 2012; Biosample/Treatment: cell line, A549/iressa, gleevec, crizotinib; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
Curated Info

40

Rikova K (2012) CST Curation Set: 16137; Year: 2012; Biosample/Treatment: cell line, MKN45/crizotinib; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
Curated Info

41

Rikova K (2012) CST Curation Set: 16138; Year: 2012; Biosample/Treatment: cell line, H3255/iressa; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
Curated Info

42

Rikova K (2012) CST Curation Set: 16142; Year: 2012; Biosample/Treatment: cell line, H3255/iressa; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST](AGC)
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43

Rikova K (2012) CST Curation Set: 16139; Year: 2012; Biosample/Treatment: cell line, H1703/gleevec; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
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Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
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Bai Y, et al. (2012) Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors. Cancer Res 72, 2501-11
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47

Zhou J (2012) CST Curation Set: 14432; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

48

Stokes MP, et al. (2012) PTMScan Direct: Identification and Quantification of Peptides from Critical Signaling Proteins by Immunoaffinity Enrichment Coupled with LC-MS/MS. Mol Cell Proteomics 11, 187-201
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Franz-Wachtel M, et al. (2012) Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells. Mol Cell Proteomics 11, 160-70
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50

Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
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51

Rikova K (2012) CST Curation Set: 14270; Year: 2012; Biosample/Treatment: cell line, Tumor pilot study 1mg/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

52

Rikova K (2012) CST Curation Set: 14271; Year: 2012; Biosample/Treatment: cell line, Tumor pilot study 2mg/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

53

Mulhern D (2012) CST Curation Set: 14193; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

54

Zhou J (2012) CST Curation Set: 14185; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

55

Zhou J (2012) CST Curation Set: 14105; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

56

Zhou J (2012) CST Curation Set: 14107; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

57

Possemato A (2012) CST Curation Set: 14060; Year: 2012; Biosample/Treatment: cell line, H1650/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]
Curated Info

58

Possemato A (2012) CST Curation Set: 14061; Year: 2012; Biosample/Treatment: cell line, H1650/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]
Curated Info

59

Possemato A (2012) CST Curation Set: 14062; Year: 2012; Biosample/Treatment: cell line, H1650/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]
Curated Info

60

Possemato A (2012) CST Curation Set: 14063; Year: 2012; Biosample/Treatment: cell line, H1650/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]
Curated Info

61

Possemato A (2012) CST Curation Set: 14058; Year: 2012; Biosample/Treatment: cell line, H1650/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]
Curated Info

62

Possemato A (2012) CST Curation Set: 14059; Year: 2012; Biosample/Treatment: cell line, H1650/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]
Curated Info

63

Zhou J (2012) CST Curation Set: 14007; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

64

Zhou J (2012) CST Curation Set: 14008; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

65

Zhou J (2012) CST Curation Set: 13888; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

66

Zhou J (2012) CST Curation Set: 13889; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

67

Zhou J (2012) CST Curation Set: 13898; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

68

Zhou J (2012) CST Curation Set: 13899; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

69

Zhou J (2012) CST Curation Set: 13884; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

70

Zhou J (2012) CST Curation Set: 13885; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

71

Zhou J (2012) CST Curation Set: 13886; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

72

Zhou J (2012) CST Curation Set: 13887; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

73

Mulhern D (2012) CST Curation Set: 13933; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

74

Rikova K (2012) CST Curation Set: 13915; Year: 2012; Biosample/Treatment: cell line, Mix of TMT treated cell lines 1/treated; Disease: -; SILAC: -;
Curated Info

75

Rikova K (2012) CST Curation Set: 13916; Year: 2012; Biosample/Treatment: cell line, Mix of TMT treated cell lines 2/treated; Disease: -; SILAC: -;
Curated Info

76

Mulhern D (2012) CST Curation Set: 13830; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: (K/R)XpSX(K/R)
Curated Info

77

Zhou J (2012) CST Curation Set: 13839; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

78

Tucker M (2012) CST Curation Set: 13492; Year: 2012; Biosample/Treatment: cell line, 23132/87[RAIG1(knockdown)]/GPRC5A knockdown; Disease: gastric cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

79

Tucker M (2012) CST Curation Set: 13493; Year: 2012; Biosample/Treatment: cell line, 23132/87[RAIG1(knockdown)]/GPRC5A knockdown; Disease: gastric cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

80

Tucker M (2012) CST Curation Set: 13494; Year: 2012; Biosample/Treatment: cell line, 23132/87/untreated; Disease: gastric cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

81

Mulhern D (2012) CST Curation Set: 13107; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

82

Mulhern D (2012) CST Curation Set: 13108; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY])
Curated Info

83

Rikova K (2012) CST Curation Set: 13730; Year: 2012; Biosample/Treatment: cell line, Mix of TMT treated cell lines 2/treated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

84

Rikova K (2012) CST Curation Set: 13731; Year: 2012; Biosample/Treatment: cell line, Mix of TMT treated cell lines 3/treated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

85

Rikova K (2012) CST Curation Set: 13729; Year: 2012; Biosample/Treatment: cell line, Mix of TMT treated cell lines 1/treated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

86

Zhou J (2012) CST Curation Set: 13688; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

87

Zhou J (2012) CST Curation Set: 13689; Year: 2012; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) Rabbit mAb Cat#: 8954, Phospho-Tyrosine Rabbit mAb (p-Tyr-1000) Immunoaffinity Beads Cat#: 8876
Curated Info

88