Ser693
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Home > Phosphorylation Site Page: > Ser693  -  DRP1 (human)

Site Information
LVGQLYKsSLLDDLL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27276100

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 ) , SH-SY5Y (neural crest) ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 1 )
Kinases, in vitro:
GSK3B (human) ( 1 )
Treatments:
lithium ( 1 )

Downstream Regulation
Effects of modification on DRP1:
enzymatic activity, inhibited ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Chou CH, et al. (2012) GSK3beta-Mediated Drp1 Phosphorylation Induced Elongated Mitochondrial Morphology against Oxidative Stress. PLoS One 7, e49112
23185298   Curated Info

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