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Site Information |
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SMPLDQysPsFPDTR SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 2721300 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Putative in vivo kinases: | |
Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on FGFR1: | |
Effects of modification on biological processes: |
References | |
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Szybowska P, et al. (2019) Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway. Cells 8
31146385 Curated Info |
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Nadratowska-Wesolowska B, et al. (2014) RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789. Oncogene 33, 4823-36
24141780 Curated Info |
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Zakrzewska M, et al. (2013) ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling. Sci Signal 6, ra11
23405013 Curated Info |
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Sørensen V, et al. (2008) Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus. Mol Cell Biol 28, 4129-41
18411303 Curated Info |