Ser158
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Home > Phosphorylation Site Page: > Ser158  -  IRF5 (human)

Site Information
QRMLPSLsLTEDVKW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27101102

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
fibrosarcoma of soft tissue ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , HT1080 (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
TBK1 (human) ( 1 )
Kinases, in vitro:
TBK1 (human) ( 1 )

Downstream Regulation
Effects of modification on IRF5:
intracellular localization ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 )

References 

1

Chang Foreman HC, Van Scoy S, Cheng TF, Reich NC (2012) Activation of interferon regulatory factor 5 by site specific phosphorylation. PLoS One 7, e33098
22412986   Curated Info

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