Tyr76

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Home > Phosphorylation Site Page: > Tyr76 - p21Cip1 (mouse)

Site Information
SLGLPKVyLsPGSRS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 26400605

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293T (epithelial) ( 1 ) , DF1 (fibroblast) ( 1 )

Upstream Regulation
Kinases, in vitro:	Abl (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	carcinogenesis, induced ( 1 ) , cell growth, induced ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:	glioma ( 1 )

References
1	Hukkelhoven E, et al. (2012) Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma. J Biol Chem 287, 38523-30 23007395 Curated Info

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