Tyr76
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Home > Phosphorylation Site Page: > Tyr76  -  p21Cip1 (mouse)

Site Information
SLGLPKVyLsPGSRS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 26400605

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
DF1 (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Kinases, in vitro:
Abl (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell growth, induced ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
glioma ( 1 )

References 

1

Hukkelhoven E, et al. (2012) Tyrosine phosphorylation of the p21 cyclin-dependent kinase inhibitor facilitates the development of proneural glioma. J Biol Chem 287, 38523-30
23007395   Curated Info

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