Ser1344
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Home > Phosphorylation Site Page: > Ser1344  -  SIPA1L1 (rat)

Site Information
LQGTSADsGIDtASY   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 26348503

In vivo Characterization
Methods used to characterize site in vivo:
microscopy-colocalization with upstream kinase ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , neuron-'brain, hippocampus' ( 1 )

Upstream Regulation
Regulatory protein:
PLK2 (rat) ( 1 )

Downstream Regulation
Effects of modification on SIPA1L1:
molecular association, regulation ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Induce interaction with:
BTRC (human) ( 1 )

References 

1

Ang XL, Seeburg DP, Sheng M, Harper JW (2008) Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons. J Biol Chem 283, 29424-32
18723513   Curated Info

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