Ser179

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Home > Phosphorylation Site Page: > Ser179 - PPAR-alpha (human)

Site Information
RFGRMPRsEKAKLkA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 457549

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Disease tissue studied:	liver cancer ( 1 )
Relevant cell line - cell type - tissue:	Huh7 (hepatic) ( 1 )

Upstream Regulation
Kinases, in vitro:	PKCA (human) ( 1 ) , PKCB iso2 (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	transcription, altered ( 1 )

References
1	Blanquart C, et al. (2004) The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha. Mol Endocrinol 18, 1906-18 15131257 Curated Info

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