Ser229
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Home > Phosphorylation Site Page: > Ser229  -  Kv1.4 (rat)

Site Information
FFDRNRPsFDAILYY   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 457537

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'neuron, cortical'-brain ( 1 ) , 293 (epithelial) ( 1 )

Upstream Regulation
Regulatory protein:
Akt1 (rat) ( 1 ) , NMDAR1 (rat) ( 1 ) , PKACA (rat) ( 1 )
Kinases, in vitro:
PKACA (rat) ( 1 )
Treatments:
A-443654 ( 1 ) , Ba(2+) ( 1 ) , cAMP_analog ( 1 ) , CNQX ( 1 ) , colforsin ( 1 ) , EDTA ( 1 ) , glutamic acid ( 1 ) , H-89 ( 1 ) , insulin ( 1 ) , KN-62 ( 1 ) , low_K(+) ( 1 ) , LY294002 ( 1 ) , MK801 ( 1 ) , nifedipine ( 1 ) , NMDA ( 1 ) , TEA ( 1 ) , TTX ( 1 ) , wortmannin ( 1 )

Downstream Regulation
Effects of modification on Kv1.4:
intracellular localization ( 1 )

References 

1

Tao Y, et al. (2005) Neuronal transmission stimulates the phosphorylation of Kv1.4 channel at Ser229 through protein kinase A1. J Neurochem 94, 1512-22
16000151   Curated Info