Thr404

Site Information
SSMSTEQtLAsDTDS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 447650

In vivo Characterization
Methods used to characterize site in vivo:	phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:	cervical cancer ( 1 ) , cervical squamous cell carcinoma ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , KB (squamous) ( 1 )

Upstream Regulation
Regulatory protein:	MKK7 (human) ( 1 )
Kinases, in vitro:	CK2A1 (human) ( 1 ) , MKK7 (human) ( 1 )
Treatments:	anisomycin ( 1 ) , IL-1a ( 1 ) , osmotic_stress ( 1 ) , TNF ( 1 ) , UV ( 1 )

References
1	Fleming Y, et al. (2000) Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. Biochem J 352 Pt 1, 145-54 11062067 Curated Info