Thr274
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Home > Phosphorylation Site Page: > Thr274  -  VASP (rat)

Site Information
LARRRKAtQVGEKPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448381

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 , 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'muscle, skeletal' ( 2 ) , vessel ( 2 ) , VSMC ('muscle, smooth') ( 1 )

Upstream Regulation
Treatments:
acadesine ( 1 ) , compound_C ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell motility, inhibited ( 1 ) , cytoskeletal reorganization ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
type 2 diabetes ( 2 )

References 

1

Stone JD, et al. (2013) AMP-activated protein kinase inhibits vascular smooth muscle cell proliferation and migration and vascular remodeling following injury. Am J Physiol Heart Circ Physiol 304, H369-81
23203966   Curated Info

2

Blume C, et al. (2007) AMP-activated protein kinase impairs endothelial actin cytoskeleton assembly by phosphorylating vasodilator-stimulated phosphoprotein. J Biol Chem 282, 4601-12
17082196   Curated Info